Angiotensin Converting Enzyme Inhibitors (ACEI)
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Angiotensin Converting Enzyme Inhibitors (ACEI)

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Questions and Answers

What is the primary mechanism of action of Angiotensin Converting Enzyme Inhibitors (ACEI)?

  • Inhibit the conversion of angiotensin I to angiotensin II (correct)
  • Block the effects of aldosterone
  • Increase the production of angiotensin II
  • Promote the retention of sodium
  • Which condition is NOT an indication for using Angiotensin Converting Enzyme Inhibitors (ACEI)?

  • Chronic kidney disease
  • Heart failure
  • Hypertension (HTN)
  • Diabetes mellitus (correct)
  • What is a potential side effect associated with the use of Captopril?

  • Gastritis
  • Rash
  • Pulmonary edema
  • Neutropenia (correct)
  • Which of the following is a significant adverse effect of Angiotensin Converting Enzyme Inhibitors?

    <p>Angioedema</p> Signup and view all the answers

    Which statement accurately reflects the black box warning for ACE inhibitors?

    <p>Teratogenic effects in pregnancy</p> Signup and view all the answers

    Study Notes

    Angiotensin Converting Enzyme Inhibitors (ACEI)

    • ACEIs are a drug class that inhibits the conversion of angiotensin I to angiotensin II
    • Angiotensin II is a potent vasoconstrictor
    • ACEIs are indicated for the treatment of hypertension, acute coronary syndrome (ACS), chronic kidney disease, stroke prevention, and heart failure
    • Two common ACEIs are lisinopril (Zestril) and captopril (Capoten)
    • Side Effects (SE) and Adverse Effects (AE) of ACEIs include:
      • Kidney injury
      • Angioedema (swelling of the face, lips, tongue, and throat)
      • Cough
      • Hyperkalemia (high potassium levels in the blood)
    • Black Box Warning: ACEIs are teratogenic (can cause birth defects) and should not be used during pregnancy.
    • Captopril can specifically cause neutropenia (low white blood cell count)

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    Description

    This quiz covers the essential aspects of Angiotensin Converting Enzyme Inhibitors (ACEIs). Learn about their mechanisms, indications, common medications, side effects, and important warnings. Ideal for students and healthcare professionals alike.

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