Analysis of Urine & Bodily Fluids: Glomerular Disorders

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Questions and Answers

What is the primary characteristic of Focal Segmental Glomerulosclerosis (FSGS)?

  • It affects only certain areas of glomeruli (correct)
  • It affects all glomeruli uniformly
  • It is a disorder of collagen production
  • It affects the proximal convoluted tubules

Which of the following is NOT a common cause or association of FSGS?

  • Alport Syndrome (correct)
  • HIV and hepatitis viruses
  • Abuse of heroin and analgesics
  • Exposure to heavy metals

What is a common finding on urinalysis in patients with FSGS?

  • Glycosuria with normal blood glucose
  • Low urinary pH due to bicarbonate reabsorption failure
  • Moderate to heavy proteinuria and microscopic hematuria (correct)
  • Presence of renal tubular epithelial cell casts

What is the characteristic finding in Fanconi Syndrome?

<p>Generalized failure of tubular reabsorption in the proximal convoluted tubule (D)</p> Signup and view all the answers

Which of the following is the primary disorder associated with damage to renal tubules?

<p>Acute Tubular Necrosis (B)</p> Signup and view all the answers

Which of the following is a characteristic finding in Alport Syndrome?

<p>Macroscopic hematuria in males (C)</p> Signup and view all the answers

What is the most common cause of glomerulonephritis characterized by the deposition of immune complexes containing IgA on the glomerular membrane?

<p>Immunoglobulin A Nephropathy (B)</p> Signup and view all the answers

Which glomerulonephritis condition presents with an episode of macroscopic hematuria after an infection or strenuous exercise?

<p>Membranous Glomerulonephritis (C)</p> Signup and view all the answers

Which glomerulonephritis condition is associated with a perinuclear pattern (p-ANCA) on ANCA testing due to ethanol fixation?

<p>Granulomatosis with Polyangiitis (GPA) (A)</p> Signup and view all the answers

What condition is primarily seen in children after upper respiratory infections and involves symptoms like raised, red patches on the skin?

<p>Henoch-Schönlein Purpura (D)</p> Signup and view all the answers

Which glomerulonephritis condition leads to significant thickening of the glomerular basement membrane due to the deposition of immunoglobulin G immune complexes?

<p>Membranous Glomerulonephritis (B)</p> Signup and view all the answers

What is the primary cause of end-stage renal disease (ESRD) in patients with Berger disease over time?

<p>Chronic Glomerulonephritis (C)</p> Signup and view all the answers

Which glomerulonephritis condition is most common in children, presenting with edema, heavy proteinuria, transient hematuria, and normal BUN and creatinine levels?

<p>Minimal Change Disease (A)</p> Signup and view all the answers

What condition is characterized by massive proteinuria, low serum albumin, high serum lipids, and edema due to damage to the glomerular membrane?

<p>Nephrotic syndrome (D)</p> Signup and view all the answers

What risk is associated with Minimal Change Disease in terms of lipid production and fluid retention?

<p>Decreased oncotic pressure (C)</p> Signup and view all the answers

Which glomerulonephritis condition involves elevated serum levels of IgA typically resulting from a mucosal infection?

<p>Immunoglobulin A Nephropathy (B)</p> Signup and view all the answers

Which of the following is a characteristic of glomerular disorders?

<p>Immune complexes deposit on the glomerular membranes (C)</p> Signup and view all the answers

What is the primary cause of acute poststreptococcal glomerulonephritis?

<p>Immune complexes formed with streptococcal antigens (C)</p> Signup and view all the answers

What is the primary feature of Goodpasture syndrome?

<p>Autoantibodies against glomerular and alveolar basement membranes (A)</p> Signup and view all the answers

Which of the following is a common urinalysis finding in acute poststreptococcal glomerulonephritis?

<p>Presence of RBC casts (D)</p> Signup and view all the answers

Which of the following is a common finding in rapidly progressive (crescentic) glomerulonephritis?

<p>Increased fibrin degradation products (C)</p> Signup and view all the answers

Which antibody is significant in the diagnosis of granulomatosis with polyangiitis (GPA)?

<p>Anti-neutrophilic cytoplasmic antibodies (ANCA) (B)</p> Signup and view all the answers

What is a common cause of nonimmunologic glomerular damage?

<p>Exposure to chemicals and toxins (C)</p> Signup and view all the answers

Which of the following is a characteristic of rapidly progressive (crescentic) glomerulonephritis?

<p>Rapid onset and progression to renal failure (B)</p> Signup and view all the answers

What is a common symptom of acute poststreptococcal glomerulonephritis?

<p>Edema, particularly around the eyes (A)</p> Signup and view all the answers

Which of the following is a potential complication of Goodpasture syndrome?

<p>Chronic glomerulonephritis and end-stage renal failure (C)</p> Signup and view all the answers

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