Aminoglycosides Antibiotics Overview

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Questions and Answers

Which adverse effect should the nurse monitor for in a client receiving aminoglycosides?

  • Tendon rupture (correct)
  • Optic nerve dysfunction
  • Mood alteration
  • Rash and pruritus

What is a contraindication for the use of fluoroquinolones?

  • Mild headache
  • Pregnancy (correct)
  • Nausea and vomiting
  • Hypersensitivity

What is a precaution when administering aminoglycosides to a client?

  • Mix with penicillin in IV solution
  • Administer with loop diuretics
  • Use for clients with myasthenia gravis
  • Use in clients with hearing loss (correct)

Which medication interaction increases the risk of nephrotoxicity when given with aminoglycosides?

<p>Vancomycin (B)</p> Signup and view all the answers

What should patients avoid to help preserve probiotic activity when taking antibacterial or antifungal drugs?

<p>Administering probiotics 2 hours after dosing with antibacterial or antifungal drugs (B)</p> Signup and view all the answers

Which statement about aminoglycosides is accurate?

<p>Lower doses are needed for clients with hearing loss (D)</p> Signup and view all the answers

What should be reported immediately by a client taking streptomycin?

<p>Optic nerve dysfunction (D)</p> Signup and view all the answers

Which type of antibiotics are aminoglycosides?

<p>Bactericidal antibiotics (C)</p> Signup and view all the answers

What is the prototype drug of the aminoglycosides class?

<p>Gentamycin (D)</p> Signup and view all the answers

Which type of infections can streptomycin be used to treat?

<p>Tuberculosis (D)</p> Signup and view all the answers

What is the purpose of using oral neomycin before colorectal surgery?

<p>To suppress normal flora in the GI tract (C)</p> Signup and view all the answers

Which adverse effect of aminoglycosides is related to cochlear and vestibular damage?

<p>Ototoxicity (B)</p> Signup and view all the answers

What type of infection can paromomycin treat?

<p>Intestinal amebiasis (C)</p> Signup and view all the answers

What should be monitored to assess nephrotoxicity in a patient taking aminoglycosides?

<p>Urine output, BUN, creatinine levels (C)</p> Signup and view all the answers

Which of the following manifestations indicates possible ototoxicity from aminoglycosides?

<p>Tinnitus and hearing loss (D)</p> Signup and view all the answers

Why are newer medications like ethambutol preferred over streptomycin for treating tuberculosis?

<p>Lower toxicity profile (C)</p> Signup and view all the answers

What is the purpose of doing baseline audiometric studies before administering aminoglycosides?

<p>To detect early signs of ototoxicity (C)</p> Signup and view all the answers

What is a common adverse effect associated with fluoroquinolones?

<p>Joint pain (B)</p> Signup and view all the answers

Why should a client with kidney impairment receive lower doses of aminoglycosides?

<p>To minimize nephrotoxicity (A)</p> Signup and view all the answers

What is a significant precaution when administering aminoglycosides to clients with myasthenia gravis?

<p>Closely assessing for muscle weakness (B)</p> Signup and view all the answers

Which class of medications should be avoided when taking aminoglycosides to prevent nephrotoxicity?

<p>Cephalosporins (D)</p> Signup and view all the answers

What should be closely monitored in a client receiving aminoglycosides to prevent ototoxicity?

<p>Hearing changes (D)</p> Signup and view all the answers

Why do pregnant women need to avoid fluoroquinolones if no other treatment is available?

<p>Due to the risk of teratogenic effects on the fetus (A)</p> Signup and view all the answers

What action should be taken if a client on aminoglycosides experiences tingling and numbness in the hands and feet?

<p>&quot;Report manifestations to the healthcare provider&quot; (A)</p> Signup and view all the answers

"When should blood samples be obtained for measuring trough levels of aminoglycosides?"

<p>&quot;Right before the next dose&quot; (D)</p> Signup and view all the answers

What type of antibiotics are aminoglycosides?

<p>Broad-spectrum (B)</p> Signup and view all the answers

Which adverse effect should be monitored in a client receiving aminoglycosides?

<p>Nephrotoxicity (C)</p> Signup and view all the answers

What is the purpose of using paromomycin?

<p>Treating intestinal amebiasis (D)</p> Signup and view all the answers

Which symptom should be reported immediately by a client taking aminoglycosides?

<p>Hematuria (A)</p> Signup and view all the answers

Why is streptomycin less preferred for treating tuberculosis compared to newer medications?

<p>Severe side effects (A)</p> Signup and view all the answers

Which condition is neomycin used to treat topically?

<p>Eye infections (A)</p> Signup and view all the answers

What is a significant adverse effect of aminoglycosides related to hearing loss?

<p>Vertigo (A)</p> Signup and view all the answers

In what way does oral neomycin help in preparation for colorectal surgery?

<p>Reduces risk of secondary infections (B)</p> Signup and view all the answers

What is the mechanism of action of aminoglycosides in destroying microorganisms?

<p>Inhibition of protein synthesis (C)</p> Signup and view all the answers

What adverse effect requires baseline audiometric studies before taking aminoglycosides?

<p>Ototoxicity (B)</p> Signup and view all the answers

What is the primary method by which aminoglycosides destroy microorganisms?

<p>Disruption of protein synthesis (D)</p> Signup and view all the answers

Which adverse effect of aminoglycosides is characterized by proteinuria, casts in the urine, and elevated BUN and creatinine levels?

<p>Nephrotoxicity (B)</p> Signup and view all the answers

For what purpose is streptomycin primarily used in combination with other medications?

<p>To treat tuberculosis (C)</p> Signup and view all the answers

Which medication would be preferred over streptomycin for treating tuberculosis due to safety concerns?

<p>Ethambutol (A)</p> Signup and view all the answers

What is the most critical adverse effect that should be monitored in a client receiving aminoglycosides to prevent cochlear and vestibular damage?

<p>Neurotoxicity (A)</p> Signup and view all the answers

Which antibiotic suppresses the normal flora of the GI tract preoperatively for colorectal surgery?

<p>Neomycin (C)</p> Signup and view all the answers

What specific symptom requires immediate reporting by a patient on aminoglycosides to prevent severe adverse effects?

<p>Tinnitus (A)</p> Signup and view all the answers

Which antibiotic is known for treating intestinal amebiasis and tapeworm infections?

<p>Paromomycin (D)</p> Signup and view all the answers

Which type of infection can streptomycin treat when used in combination with other medications?

<p>Tuberculosis (B)</p> Signup and view all the answers

What adverse effect of aminoglycosides is related to sensory nerve damage characterized by tingling and numbness in the extremities?

<p>Neurotoxicity (A)</p> Signup and view all the answers

What is a potential adverse effect associated with fluoroquinolones besides gastrointestinal effects?

<p>Tendon rupture (C)</p> Signup and view all the answers

Which of the following is a common allergic reaction associated with aminoglycosides?

<p>Urticaria (C)</p> Signup and view all the answers

What is the primary purpose of obtaining blood samples for measuring trough levels of aminoglycosides?

<p>Assess for nephrotoxicity (B)</p> Signup and view all the answers

In patients with kidney impairment, why should lower doses of aminoglycosides be administered?

<p>To reduce the risk of nephrotoxicity (C)</p> Signup and view all the answers

Which class of medications should be avoided when administering aminoglycosides to prevent nephrotoxicity?

<p>Loop diuretics (A)</p> Signup and view all the answers

What condition should be closely monitored in a client receiving aminoglycosides to prevent ototoxicity?

<p>Hearing loss (B)</p> Signup and view all the answers

Which manifestation indicates potential neurologic adverse effects of streptomycin?

<p>Tingling/numbness of hands and feet (D)</p> Signup and view all the answers

Why are newer medications preferred over streptomycin for treating tuberculosis?

<p>Reduced risk of neurologic disorders (D)</p> Signup and view all the answers

What is a significant precaution when administering aminoglycosides to clients with myasthenia gravis?

<p>Use cautiously due to neurologic effects (B)</p> Signup and view all the answers

What is an important precaution when administering aminoglycosides to clients with myasthenia gravis?

<p>Avoiding the use of aminoglycosides (D)</p> Signup and view all the answers

Which antibiotic interaction increases the risk of nephrotoxicity when given with aminoglycosides?

<p>Vancomycin (A)</p> Signup and view all the answers

What adverse effect should be closely monitored in a client receiving aminoglycosides to prevent ototoxicity?

<p>Hearing loss (C)</p> Signup and view all the answers

Why should clients with kidney impairment receive lower doses of aminoglycosides?

<p>To reduce the risk of nephrotoxicity (C)</p> Signup and view all the answers

What is a common adverse effect of fluoroquinolones besides gastrointestinal effects?

<p>Tendon rupture (C)</p> Signup and view all the answers

What is an important precaution when administering aminoglycosides to clients with myasthenia gravis?

<p>Avoiding the use of aminoglycosides (B)</p> Signup and view all the answers

What is an important precaution when administering aminoglycosides to clients with myasthenia gravis?

<p>Avoiding the use of aminoglycosides (A)</p> Signup and view all the answers

What is the primary mechanism of action of aminoglycosides in destroying microorganisms?

<p>Disrupting protein synthesis (A)</p> Signup and view all the answers

Which antibiotic can be used to treat severe uncommon infections such as tularemia, plague, and brucellosis?

<p>Gentamycin (C)</p> Signup and view all the answers

What is the specific purpose of using oral neomycin in preparation for colorectal surgery?

<p>Suppress normal flora of the GI tract (B)</p> Signup and view all the answers

Which adverse effect of aminoglycosides is characterized by proteinuria, casts in the urine, dilute urine, and elevated BUN and creatinine levels?

<p>Nephrotoxicity (D)</p> Signup and view all the answers

Which symptom should be closely monitored in a patient receiving aminoglycosides to prevent cochlear damage?

<p>Tinnitus (A)</p> Signup and view all the answers

Which antibiotic is preferred over streptomycin for treating tuberculosis due to safety concerns?

<p>Ethambutol (D)</p> Signup and view all the answers

What adverse effect of aminoglycosides is related to sensory nerve damage characterized by tingling and numbness in the extremities?

<p>Neurotoxicity (B)</p> Signup and view all the answers

Which antibiotic treats aerobic gram-negative bacilli like E. coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa?

<p>Gentamycin (B)</p> Signup and view all the answers

What action should be taken if manifestations of ototoxicity occur in a patient receiving aminoglycosides?

<p>Stop the aminoglycoside medication. (B)</p> Signup and view all the answers

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