70 Questions
Which adverse effect should the nurse monitor for in a client receiving aminoglycosides?
Tendon rupture
What is a contraindication for the use of fluoroquinolones?
Pregnancy
What is a precaution when administering aminoglycosides to a client?
Use in clients with hearing loss
Which medication interaction increases the risk of nephrotoxicity when given with aminoglycosides?
Vancomycin
What should patients avoid to help preserve probiotic activity when taking antibacterial or antifungal drugs?
Administering probiotics 2 hours after dosing with antibacterial or antifungal drugs
Which statement about aminoglycosides is accurate?
Lower doses are needed for clients with hearing loss
What should be reported immediately by a client taking streptomycin?
Optic nerve dysfunction
Which type of antibiotics are aminoglycosides?
Bactericidal antibiotics
What is the prototype drug of the aminoglycosides class?
Gentamycin
Which type of infections can streptomycin be used to treat?
Tuberculosis
What is the purpose of using oral neomycin before colorectal surgery?
To suppress normal flora in the GI tract
Which adverse effect of aminoglycosides is related to cochlear and vestibular damage?
Ototoxicity
What type of infection can paromomycin treat?
Intestinal amebiasis
What should be monitored to assess nephrotoxicity in a patient taking aminoglycosides?
Urine output, BUN, creatinine levels
Which of the following manifestations indicates possible ototoxicity from aminoglycosides?
Tinnitus and hearing loss
Why are newer medications like ethambutol preferred over streptomycin for treating tuberculosis?
Lower toxicity profile
What is the purpose of doing baseline audiometric studies before administering aminoglycosides?
To detect early signs of ototoxicity
What is a common adverse effect associated with fluoroquinolones?
Joint pain
Why should a client with kidney impairment receive lower doses of aminoglycosides?
To minimize nephrotoxicity
What is a significant precaution when administering aminoglycosides to clients with myasthenia gravis?
Closely assessing for muscle weakness
Which class of medications should be avoided when taking aminoglycosides to prevent nephrotoxicity?
Cephalosporins
What should be closely monitored in a client receiving aminoglycosides to prevent ototoxicity?
Hearing changes
Why do pregnant women need to avoid fluoroquinolones if no other treatment is available?
Due to the risk of teratogenic effects on the fetus
What action should be taken if a client on aminoglycosides experiences tingling and numbness in the hands and feet?
"Report manifestations to the healthcare provider"
"When should blood samples be obtained for measuring trough levels of aminoglycosides?"
"Right before the next dose"
What type of antibiotics are aminoglycosides?
Broad-spectrum
Which adverse effect should be monitored in a client receiving aminoglycosides?
Nephrotoxicity
What is the purpose of using paromomycin?
Treating intestinal amebiasis
Which symptom should be reported immediately by a client taking aminoglycosides?
Hematuria
Why is streptomycin less preferred for treating tuberculosis compared to newer medications?
Severe side effects
Which condition is neomycin used to treat topically?
Eye infections
What is a significant adverse effect of aminoglycosides related to hearing loss?
Vertigo
In what way does oral neomycin help in preparation for colorectal surgery?
Reduces risk of secondary infections
What is the mechanism of action of aminoglycosides in destroying microorganisms?
Inhibition of protein synthesis
What adverse effect requires baseline audiometric studies before taking aminoglycosides?
Ototoxicity
What is the primary method by which aminoglycosides destroy microorganisms?
Disruption of protein synthesis
Which adverse effect of aminoglycosides is characterized by proteinuria, casts in the urine, and elevated BUN and creatinine levels?
Nephrotoxicity
For what purpose is streptomycin primarily used in combination with other medications?
To treat tuberculosis
Which medication would be preferred over streptomycin for treating tuberculosis due to safety concerns?
Ethambutol
What is the most critical adverse effect that should be monitored in a client receiving aminoglycosides to prevent cochlear and vestibular damage?
Neurotoxicity
Which antibiotic suppresses the normal flora of the GI tract preoperatively for colorectal surgery?
Neomycin
What specific symptom requires immediate reporting by a patient on aminoglycosides to prevent severe adverse effects?
Tinnitus
Which antibiotic is known for treating intestinal amebiasis and tapeworm infections?
Paromomycin
Which type of infection can streptomycin treat when used in combination with other medications?
Tuberculosis
What adverse effect of aminoglycosides is related to sensory nerve damage characterized by tingling and numbness in the extremities?
Neurotoxicity
What is a potential adverse effect associated with fluoroquinolones besides gastrointestinal effects?
Tendon rupture
Which of the following is a common allergic reaction associated with aminoglycosides?
Urticaria
What is the primary purpose of obtaining blood samples for measuring trough levels of aminoglycosides?
Assess for nephrotoxicity
In patients with kidney impairment, why should lower doses of aminoglycosides be administered?
To reduce the risk of nephrotoxicity
Which class of medications should be avoided when administering aminoglycosides to prevent nephrotoxicity?
Loop diuretics
What condition should be closely monitored in a client receiving aminoglycosides to prevent ototoxicity?
Hearing loss
Which manifestation indicates potential neurologic adverse effects of streptomycin?
Tingling/numbness of hands and feet
Why are newer medications preferred over streptomycin for treating tuberculosis?
Reduced risk of neurologic disorders
What is a significant precaution when administering aminoglycosides to clients with myasthenia gravis?
Use cautiously due to neurologic effects
What is an important precaution when administering aminoglycosides to clients with myasthenia gravis?
Avoiding the use of aminoglycosides
Which antibiotic interaction increases the risk of nephrotoxicity when given with aminoglycosides?
Vancomycin
What adverse effect should be closely monitored in a client receiving aminoglycosides to prevent ototoxicity?
Hearing loss
Why should clients with kidney impairment receive lower doses of aminoglycosides?
To reduce the risk of nephrotoxicity
What is a common adverse effect of fluoroquinolones besides gastrointestinal effects?
Tendon rupture
What is an important precaution when administering aminoglycosides to clients with myasthenia gravis?
Avoiding the use of aminoglycosides
What is an important precaution when administering aminoglycosides to clients with myasthenia gravis?
Avoiding the use of aminoglycosides
What is the primary mechanism of action of aminoglycosides in destroying microorganisms?
Disrupting protein synthesis
Which antibiotic can be used to treat severe uncommon infections such as tularemia, plague, and brucellosis?
Gentamycin
What is the specific purpose of using oral neomycin in preparation for colorectal surgery?
Suppress normal flora of the GI tract
Which adverse effect of aminoglycosides is characterized by proteinuria, casts in the urine, dilute urine, and elevated BUN and creatinine levels?
Nephrotoxicity
Which symptom should be closely monitored in a patient receiving aminoglycosides to prevent cochlear damage?
Tinnitus
Which antibiotic is preferred over streptomycin for treating tuberculosis due to safety concerns?
Ethambutol
What adverse effect of aminoglycosides is related to sensory nerve damage characterized by tingling and numbness in the extremities?
Neurotoxicity
Which antibiotic treats aerobic gram-negative bacilli like E. coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa?
Gentamycin
What action should be taken if manifestations of ototoxicity occur in a patient receiving aminoglycosides?
Stop the aminoglycoside medication.
Learn about aminoglycosides, bactericidal antibiotics that disrupt protein synthesis. Explore the prototype gentamycin and its indications, including treatment for aerobic gram negative bacilli like E.coli and pseudomonas aeruginosa.
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