Aminoglycosides: Adverse Effects and Usage

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29 Questions

Which adverse effect is NOT associated with aminoglycosides?

Cardiotoxicity

What is the characteristic of lincosamides' spectrum of activity?

No anaerobic coverage

Which statement about tetracyclines is correct?

They can cause growth disorders of bones and teeth

What is the main mechanism of action of streptogramins?

Inhibition of protein synthesis

What is a characteristic of chloramphenicol?

It can cause aplastic anemia

What sets Amikacin apart from other aminoglycosides?

It lacks ototoxicity

What are some risks associated with long-term use of apple cider vinegar for general health?

Increased risk of hypokalemia and osteoporosis

What are the post-market issues of greatest concern for Natural Health Products (NHPs)?

Deceptive product labeling

Which of the following is NOT a risk associated with apple cider vinegar for general health?

Reduced risk of hyperreninemia

What is a common safety issue faced by the Natural Health Products industry?

Contaminated or adulterated products

Which is a potential consequence of long-term use of liquid formulations of apple cider vinegar?

Damage to tooth enamel

What is the main benefit of fatty acids in functional foods?

Decreasing the incidence of heart disease and stroke

Which bioactive component category do olive oil, canola oil, and nuts fall under in functional foods?

Fatty acids

What is the primary purpose of prebiotics and probiotics in functional foods?

Improving gut health

Which bioactive component category includes inulin, fructooligosaccharides, soy, artichokes, and garlic in functional foods?

Fiber

What is the key effect of functional foods on intestinal microflora?

Altering metabolic activities

Which category do functional foods with 'healthy' bacteria including Lactobacilli belong to?

Probiotics

What is the preferred route of administration for corticosteroids to limit systemic side effects?

Aerosol inhalation

Which adverse effect of aerosol corticosteroids can be reduced by good mouth hygiene like gargling?

Oropharyngeal candidiasis

How does cromolyn sodium and nedocromil act in the body?

By inhibiting release of mediators from mast cells

When would severe exacerbations of asthma potentially require IV methylprednisolone or oral prednisone?

In severe exacerbations of asthma

What is the first line of anti-inflammatory therapy for individuals of all ages?

Corticosteroids

How often is cromolyn sodium and nedocromil typically administered?

2-4 times a day

What is one of the recommended ways to prevent the development of desensitization of beta2 receptors and promote the efficacy of beta2 agonists?

Co-administration with corticosteroids

What adverse effect can occur due to the stimulation of beta1 receptors by beta2-adrenergic agonists?

Tachycardia

Which drug interaction makes beta2-adrenergic agonists ineffective in patients with hypertension or heart conditions?

Taking beta blockers concurrently

What is the proposed mechanism of action of methylxanthines in asthma and COPD treatment?

Relaxing airways by reducing cytoplasmic Ca2+ through cAMP elevation

In what condition are theophylline indicated as a second choice for treatment of acute attacks?

Chronic Obstructive Pulmonary Disease (COPD)

What is a potential drawback associated with the use of theophylline in asthma and COPD treatment?

Having systemic and CNS effects due to inhibiting adenosine receptors

Learn about the adverse effects and proper usage of aminoglycosides, including nephrotoxicity, neurotoxicity, and their mechanism of action. Understand their bactericidal properties, narrow spectrum of activity, and considerations for dosing and administration.

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