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Questions and Answers
Which type of organisms do aminoglycosides have a broad spectrum of activity against?
Which type of organisms do aminoglycosides have a broad spectrum of activity against?
- Fungi
- Mycobacteria (correct)
- Gram-positive bacteria
- Parasites
Which of the following are examples of drugs within the aminoglycoside class?
Which of the following are examples of drugs within the aminoglycoside class?
- Lisinopril, atorvastatin, metformin
- Penicillin, amoxicillin, cephalexin
- Ibuprofen, acetaminophen, aspirin
- Gentamicin, tobramycin, amikacin (correct)
For which condition are aminoglycosides indicated for empiric therapy?
For which condition are aminoglycosides indicated for empiric therapy?
- Allergies
- Headache
- Common cold
- Infective endocarditis (correct)
In which type of patients should aminoglycosides be used for empiric therapy?
In which type of patients should aminoglycosides be used for empiric therapy?
What is a notable characteristic of aminoglycosides in terms of drug resistance?
What is a notable characteristic of aminoglycosides in terms of drug resistance?
Flashcards
Aminoglycosides target which organisms?
Aminoglycosides target which organisms?
Mycobacteria
Examples of aminoglycosides
Examples of aminoglycosides
Gentamicin, tobramycin, amikacin
Aminoglycosides treat which heart condition?
Aminoglycosides treat which heart condition?
Infective endocarditis
Who receives aminoglycosides empirically?
Who receives aminoglycosides empirically?
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Aminoglycosides resist which bacteria?
Aminoglycosides resist which bacteria?
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Study Notes
Aminoglycosides
- Aminoglycosides have a broad spectrum of activity against gram-negative aerobic bacteria, including Pseudomonas aeruginosa.
Examples of Aminoglycosides
- Examples of drugs within the aminoglycoside class include gentamicin, tobramycin, amikacin, and streptomycin.
Indication for Empiric Therapy
- Aminoglycosides are indicated for empiric therapy in severe infections, including sepsis, malignant otitis externa, and endocarditis.
Patient Selection for Empiric Therapy
- Aminoglycosides should be used for empiric therapy in immunocompromised patients, including those with neutropenia or HIV/AIDS.
Notable Characteristic: Drug Resistance
- A notable characteristic of aminoglycosides is that they are minimally affected by beta-lactamases, making them useful against bacteria resistant to beta-lactam antibiotics.
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