Podcast
Questions and Answers
What are the two functional groups present in all amino acids?
What are the two functional groups present in all amino acids?
amine and carboxylic acid
What is the pH range at which the amino acid is overall neutral?
What is the pH range at which the amino acid is overall neutral?
pH 7-9
What is the relationship between the pKa of the carboxylic acid group and the pKa of the protonated amine group?
What is the relationship between the pKa of the carboxylic acid group and the pKa of the protonated amine group?
The pKa of the carboxylic acid group is lower than the pKa of the protonated amine group
What is the purpose of breaking down a polypeptide into its component amino acids?
What is the purpose of breaking down a polypeptide into its component amino acids?
What is the R group in an amino acid?
What is the R group in an amino acid?
What are the two functional groups present in an amino acid, other than the R group?
What are the two functional groups present in an amino acid, other than the R group?
How do D-sugars and L-sugars differ in their rotation of plane-polarized light?
How do D-sugars and L-sugars differ in their rotation of plane-polarized light?
What type of bonds connect amino acids in a peptide chain?
What type of bonds connect amino acids in a peptide chain?
How do you determine the D/L configuration of an amino acid?
How do you determine the D/L configuration of an amino acid?
What is the difference between the N-terminus and C-terminus of a peptide chain?
What is the difference between the N-terminus and C-terminus of a peptide chain?
Why can't a peptide chain be formed by simply throwing amino acids together?
Why can't a peptide chain be formed by simply throwing amino acids together?
What is the purpose of protecting groups in peptide synthesis?
What is the purpose of protecting groups in peptide synthesis?
What is the abbreviation for the protecting group commonly used for amines?
What is the abbreviation for the protecting group commonly used for amines?
What is the reagent used to couple amino acids together in peptide synthesis?
What is the reagent used to couple amino acids together in peptide synthesis?
What is the advantage of solid-phase synthesis, also known as Merrifield synthesis?
What is the advantage of solid-phase synthesis, also known as Merrifield synthesis?
What is the purpose of using a base like NaHCO3 in peptide synthesis?
What is the purpose of using a base like NaHCO3 in peptide synthesis?
What is the role of Pd/C in peptide synthesis?
What is the role of Pd/C in peptide synthesis?
