Amantadine Pharmacology Flashcards
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Questions and Answers

What are the categories of the drug Amantadine?

  • Antidepressants
  • Antihistamines
  • Antiparkinson agents (correct)
  • Antivirals (correct)

What is the expected pharmacological action of Amantadine?

Potentiates the action of dopamine in the CNS and prevents penetration of influenza A virus into host cell.

What is the therapeutic use of Amantadine?

Relief of Parkinson's symptoms and prevention/decreased symptoms of influenza A viral infection.

Amantadine is contraindicated in __________.

<p>hypersensitivity and end-stage renal disease</p> Signup and view all the answers

What should patients do if they experience worsening symptoms while using Amantadine?

<p>Notify health care professional immediately.</p> Signup and view all the answers

What is an evaluation indicator of the effectiveness of Amantadine?

<p>Decrease in akinesia and rigidity (B)</p> Signup and view all the answers

Study Notes

Amantadine Overview

  • Classified as both antiparkinson agents and antivirals.
  • Primarily used for managing Parkinson's symptoms and preventing influenza A infections.

Pharmacological Action

  • Enhances dopamine action in the central nervous system (CNS).
  • Inhibits the penetration of the influenza A virus into host cells.

Therapeutic Uses

  • Alleviates symptoms of Parkinson's disease.
  • Serves as a prophylactic measure for influenza A and helps reduce associated symptoms.

Contraindications and Precautions

  • Not advised for individuals with hypersensitivity or end-stage renal disease.
  • Patients should consult a healthcare professional before using OTC medications or consuming alcohol.
  • Report any changes in mood, confusion, difficulty urinating, edema, shortness of breath, or worsening Parkinson's symptoms.
  • Immediate consultation required if suicidal thoughts or attempts occur, or if new or worsened depression is reported.
  • Watch for influenza symptoms during amantadine prophylaxis and consult if symptoms don't improve.
  • Full therapeutic effects may take up to two weeks; effectiveness may diminish over time.
  • Gradual tapering of the drug is necessary to prevent a parkinsonian crisis.

Evaluation of Effectiveness

  • Indicators of effectiveness include decreased akinesia and rigidity.
  • Full therapeutic benefits may manifest after two weeks of treatment.
  • Successful treatment evidenced by the reduction or absence of influenza A symptoms.

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Description

Test your knowledge of Amantadine, an important drug used for treating Parkinson's disease and influenza A. This quiz covers its pharmacological actions, therapeutic uses, and contraindications. Perfect for students or healthcare professionals looking to enhance their understanding of this medication.

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