Adenovirus

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Questions and Answers

What is a characteristic hallmark of adenovirus infection in cells?

  • Apoptosis
  • Cytoplasmic vacuolation
  • Mitochondrial swelling
  • Dense, central intranuclear inclusion (correct)

Which of the following is a mode of transmission of adenovirus?

  • Vector-borne transmission
  • Direct contact (correct)
  • Contaminated food
  • All of the above

Which group is most at risk of adenovirus infection?

  • Elderly individuals
  • Pregnant women
  • Little children, military recruits, and public pools (correct)
  • Healthcare workers

What is a major cause of acute viral gastroenteritis?

<p>Adenovirus (D)</p> Signup and view all the answers

What is the significance of Penton fibers in adenovirus?

<p>They are toxic (C)</p> Signup and view all the answers

What is a common disease caused by adenovirus?

<p>Viral conjunctivitis (D)</p> Signup and view all the answers

Flashcards

Intranuclear Inclusion

The presence of densely packed materials within the nucleus of an infected cell, characteristic of adenovirus infection.

Adenovirus Transmission

Adenovirus can be spread through direct contact with infected individuals or contaminated surfaces.

Who is at risk for adenovirus?

Young children, military personnel in close quarters, and people in public swimming areas are more susceptible to adenovirus infections due to close contact and potential exposure.

Adenovirus and Gastroenteritis

Adenoviruses are a significant cause of acute gastroenteritis, often leading to diarrhea and vomiting.

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Penton fibers are toxic

Penton fibers, a component of the adenovirus structure, have toxic properties that contribute to the harmful effects of the virus.

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What disease does adenovirus cause?

Viral conjunctivitis, also known as pinkeye, is a common eye infection caused by adenovirus.

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Study Notes

Adenovirus Characteristics

  • Adenovirus is a DNA virus
  • It affects the adenoids and oropharynx

Transmission

  • Adenovirus is transmitted via respiratory droplets
  • Fecal-oral transmission also occurs
  • Direct contact is another mode of transmission

High-Risk Groups

  • Little children are at high risk of adenovirus infection
  • Military recruits are also at high risk
  • Public pools are a common location for adenovirus transmission

Disease Processes

  • Adenovirus causes tonsillitis
  • It can also cause hemorrhagic cystitis
  • Viral conjunctivitis (pink eye) is another disease process caused by adenovirus

Vaccine

  • Military recruits typically receive a live vaccine for adenovirus prevention

Adenovirus Structure and Function

  • Penton fibers of adenovirus are toxic
  • Receptor binding is a key function of adenovirus

Permissive Cells

  • Epithelial cells lining the oropharynx, respiratory, and enteric organs are permissive cells for adenovirus

Hallmark of Adenovirus

  • Dense, central intranuclear inclusion (consisting of viral DNA and protein) within an infected cell is the hallmark of adenovirus

Additional Diseases Caused

  • Adenovirus can cause acute viral gastroenteritis

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