6 Questions
What is a characteristic hallmark of adenovirus infection in cells?
Dense, central intranuclear inclusion
Which of the following is a mode of transmission of adenovirus?
Direct contact
Which group is most at risk of adenovirus infection?
Little children, military recruits, and public pools
What is a major cause of acute viral gastroenteritis?
Adenovirus
What is the significance of Penton fibers in adenovirus?
They are toxic
What is a common disease caused by adenovirus?
Viral conjunctivitis
Study Notes
Adenovirus Characteristics
- Adenovirus is a DNA virus
- It affects the adenoids and oropharynx
Transmission
- Adenovirus is transmitted via respiratory droplets
- Fecal-oral transmission also occurs
- Direct contact is another mode of transmission
High-Risk Groups
- Little children are at high risk of adenovirus infection
- Military recruits are also at high risk
- Public pools are a common location for adenovirus transmission
Disease Processes
- Adenovirus causes tonsillitis
- It can also cause hemorrhagic cystitis
- Viral conjunctivitis (pink eye) is another disease process caused by adenovirus
Vaccine
- Military recruits typically receive a live vaccine for adenovirus prevention
Adenovirus Structure and Function
- Penton fibers of adenovirus are toxic
- Receptor binding is a key function of adenovirus
Permissive Cells
- Epithelial cells lining the oropharynx, respiratory, and enteric organs are permissive cells for adenovirus
Hallmark of Adenovirus
- Dense, central intranuclear inclusion (consisting of viral DNA and protein) within an infected cell is the hallmark of adenovirus
Additional Diseases Caused
- Adenovirus can cause acute viral gastroenteritis
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