Adenovirus
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Questions and Answers

What is a characteristic hallmark of adenovirus infection in cells?

  • Apoptosis
  • Cytoplasmic vacuolation
  • Mitochondrial swelling
  • Dense, central intranuclear inclusion (correct)
  • Which of the following is a mode of transmission of adenovirus?

  • Vector-borne transmission
  • Direct contact (correct)
  • Contaminated food
  • All of the above
  • Which group is most at risk of adenovirus infection?

  • Elderly individuals
  • Pregnant women
  • Little children, military recruits, and public pools (correct)
  • Healthcare workers
  • What is a major cause of acute viral gastroenteritis?

    <p>Adenovirus</p> Signup and view all the answers

    What is the significance of Penton fibers in adenovirus?

    <p>They are toxic</p> Signup and view all the answers

    What is a common disease caused by adenovirus?

    <p>Viral conjunctivitis</p> Signup and view all the answers

    Study Notes

    Adenovirus Characteristics

    • Adenovirus is a DNA virus
    • It affects the adenoids and oropharynx

    Transmission

    • Adenovirus is transmitted via respiratory droplets
    • Fecal-oral transmission also occurs
    • Direct contact is another mode of transmission

    High-Risk Groups

    • Little children are at high risk of adenovirus infection
    • Military recruits are also at high risk
    • Public pools are a common location for adenovirus transmission

    Disease Processes

    • Adenovirus causes tonsillitis
    • It can also cause hemorrhagic cystitis
    • Viral conjunctivitis (pink eye) is another disease process caused by adenovirus

    Vaccine

    • Military recruits typically receive a live vaccine for adenovirus prevention

    Adenovirus Structure and Function

    • Penton fibers of adenovirus are toxic
    • Receptor binding is a key function of adenovirus

    Permissive Cells

    • Epithelial cells lining the oropharynx, respiratory, and enteric organs are permissive cells for adenovirus

    Hallmark of Adenovirus

    • Dense, central intranuclear inclusion (consisting of viral DNA and protein) within an infected cell is the hallmark of adenovirus

    Additional Diseases Caused

    • Adenovirus can cause acute viral gastroenteritis

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