Adenovirus Infections in Humans: Pathogenesis

Play an AI-generated podcast conversation about this lesson

What is the primary mode of transmission for adenoviruses in humans?

Through airborne transmission

By direct contact with infected individuals (correct)

Through contaminated food and water

By insect vectors

Which of the following is a characteristic of adenovirus infections in humans?

Adenoviruses typically spread beyond the regional lymph nodes

Adenoviruses are RNA viruses with a linear genome

Adenoviruses only cause overt symptoms in the gastrointestinal tract

Adenoviruses can persist as latent infections in adenoids and tonsils (correct)

What is the primary method used for laboratory diagnosis of adenovirus infections?

Serological tests to detect antibodies

Virus isolation through cell culture

Histopathological examination of tissue samples

Polymerase chain reaction (PCR) assays (correct)

Which of the following is a characteristic of the adenovirus genome?

It is a DNA virus with a linear genome Signup and view all the answers

What is the primary clinical manifestation of adenovirus infections in humans?

Asymptomatic or subclinical infections Signup and view all the answers

What is the recommended approach for collecting samples for adenovirus diagnosis?

Collect samples from multiple sites, including the affected areas, early in the illness Signup and view all the answers

Which of the following best describes the pathogenesis of adenovirus infections?

Adenoviruses infect and replicate primarily in epithelial cells of various body sites. Signup and view all the answers

Which of the following statements about adenovirus persistence is correct?

Group C adenoviruses persist as latent infections in adenoids and tonsils for years. Signup and view all the answers

What is the significance of the name 'adenovirus'?

It reflects the recovery of the initial isolate from explants of human adenoids. Signup and view all the answers

Which of the following statements about adenovirus infections in the gastrointestinal tract is correct?

Most human adenoviruses replicate in intestinal epithelium after ingestion but usually produce subclinical infections. Signup and view all the answers

Which of the following sample types should be collected early in the course of an adenovirus infection for optimal virus isolation?

Stool, urine, or swabs from affected sites Signup and view all the answers