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Questions and Answers
What is the primary focus of the experiment on acute cardiac failure in rabbits?
What is the primary focus of the experiment on acute cardiac failure in rabbits?
Which of the following is a primary dysfunction that can lead to cardiac insufficiency?
Which of the following is a primary dysfunction that can lead to cardiac insufficiency?
Which method is used to induce volume overload in the experiment?
Which method is used to induce volume overload in the experiment?
What compensatory mechanism involves increased heart rate?
What compensatory mechanism involves increased heart rate?
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What condition is NOT a cause of pressure overload in cardiac dysfunction?
What condition is NOT a cause of pressure overload in cardiac dysfunction?
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What is injected into the rabbit to prevent coagulation during the experiment?
What is injected into the rabbit to prevent coagulation during the experiment?
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During the experiment, which procedure follows the administration of anesthesia?
During the experiment, which procedure follows the administration of anesthesia?
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Which factor does NOT contribute to the cardiac compensation mechanisms?
Which factor does NOT contribute to the cardiac compensation mechanisms?
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Study Notes
Acute Cardiac Failure in Rabbits
- The purpose of the experiment is to replicate experimental acute right heart failure and understand the manifestations and mechanisms of cardiac failure.
- Acute heart failure is characterized by a rapid decrease in cardiac output over a short period of time.
- Causes of cardiac insufficiency can be grouped into three categories:
- Primary dysfunction of myocardial systole and diastole which include different types of myocarditis, myocardiopathy, myocardial necrosis, and fibrosis; myocardial ischemia; coronary artery disease; and vitamin B1 deficiency.
- Cardiac overload which includes volume overload (mitral or aortic insufficiency, chronic anemia, hyperthyroidism) and pressure overload (systemic hypertension, pulmonary hypertension).
- Restricted cardiac filling (constrictive pericarditis).
- Cardiac dysfunction leads to reduced blood supply in tissues and organs.
- The body responds with both cardiac compensation and extracardiac compensation to restore blood supply.
Cardiac Compensation
- Increased heart rate
- Positive inotropic actions of catecholamines
- Cardiac ontogenic dilation
- Myocardial hypertrophy
Extracardiac Compensation
- Increased blood volume
- Redistributed blood flow
- Erythrocytosis
- Increased tissue capability to utilize oxygen
Methods
- Pressure overload is induced by injecting paraffin liquid.
- Volume overload is induced by injecting normal saline into the heart from the ductus venosus.
Results
- (Results are shown as symbols)
Questions
- There are four types of cardiac compensation.
- The cause of heart failure is pressure overload and volume overload.
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Description
This quiz explores the mechanisms and manifestations of acute cardiac failure, particularly in rabbits. It covers the causes of cardiac insufficiency, including myocardial dysfunction, cardiac overload, and restricted filling. Participants will gain insights into the physiological responses to reduced cardiac output.
