Actinic Keratosis and Nonmelanocytic Malignant Skin Tumors
23 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What microscopic features are commonly seen in the stratum corneum of actinic keratosis?

  • Acantholysis and spongiosis
  • Hyperkeratosis and parakeratosis (correct)
  • Dermal elastosis and acanthosis
  • Acanthosis and psoriasiform hyperplasia
  • Which type of UV radiation reaches the dermis and indirectly causes DNA damage?

  • UV-C (100 nm)
  • UV-B and UV-C combined
  • UV-A (400nm) (correct)
  • UV-B (320nm)
  • What protein is primarily involved in the pathogenesis of Basal Cell Carcinoma (BCC)?

  • Hedgehog proteins
  • Merkel cell polyomavirus
  • p53 gene
  • PTCH gene- protein patched homolog 1 (correct)
  • What is a common risk factor for developing Basal Cell Carcinoma?

    <p>UV exposure</p> Signup and view all the answers

    What type of therapy involves the use of Hedgehog pathway inhibitors for treating Basal Cell Carcinoma?

    <p>Pharmacologic therapy</p> Signup and view all the answers

    Which type of Hedgehog protein is considered the most potent and most often expressed?

    <p>Sonic Hedgehog (SHH)</p> Signup and view all the answers

    What is the main function of Hedgehog proteins in cellular processes?

    <p>Cell specification, proliferation, and differentiation</p> Signup and view all the answers

    Which type of skin tumor presents as small rough spots and may have cutaneous horns?

    <p><strong>Actinic Keratosis</strong></p> Signup and view all the answers

    Which of the following is NOT a risk factor for Squamous Cell Carcinoma?

    <p>Genetic mutations in signaling pathways</p> Signup and view all the answers

    What is the typical presentation of Merkel Cell Carcinoma?

    <p>Painless nodules that grow slowly</p> Signup and view all the answers

    Which histological pattern is NOT associated with Squamous Cell Carcinoma?

    <p>Adenomatous</p> Signup and view all the answers

    Which type of cancer is derived from keratinocytes in the epidermal layer?

    <p>Squamous cell carcinoma</p> Signup and view all the answers

    What microscopic feature is characteristic of Acantholytic Squamous Cell Carcinoma?

    <p>Loss of intercellular connection (Acantholysis)</p> Signup and view all the answers

    Which neuroendocrine markers are expressed in Merkel Cell Carcinoma?

    <p>CD56 and Chromogranin</p> Signup and view all the answers

    Which cancers are associated with nevoid basal cell carcinoma syndrome?

    <p>(BCC) in skin and Medulloblastomas in brain</p> Signup and view all the answers

    What is the most common type of cutaneous T cell lymphoma?

    <p>Mycosis Fungoides</p> Signup and view all the answers

    Which of the following is a microscopic feature of the 'Patch' stage of Mycosis Fungoides?

    <p>Clustered in epidermis</p> Signup and view all the answers

    Which condition is characterized by large irregular lumps developing from plaques and has dense dermal infiltrates with cerebriform nuclei as a microscopic feature?

    <p>Plaque stage of Mycosis Fungoides</p> Signup and view all the answers

    What are the neoplastic T cells with cerebriform nuclei found in?

    <p>Sézary syndrome</p> Signup and view all the answers

    Which condition is indicated by the presence of neoplastic T cells that are positive for CD4 and negative for CD8?

    <p>Mycosis Fungoides</p> Signup and view all the answers

    Which condition is characterized by monotonous round tumor cells?

    <p>Mycosis Fungoides</p> Signup and view all the answers

    What is the common feature of the microscopic appearance in Sézary syndrome?

    <p>Tumor cells found in peripheral blood</p> Signup and view all the answers

    Which condition presents with erythroderma, lymphadenopathy, and neoplastic T cells with cerebriform nuclei?

    <p>'Plaque' stage of Mycosis Fungoides</p> Signup and view all the answers

    More Like This

    Skin Tumors Quiz
    20 questions

    Skin Tumors Quiz

    WarmheartedTourmaline avatar
    WarmheartedTourmaline
    Nonmelanocytic Malignant Skin Tumors Quiz
    22 questions
    Tumors of the Skin - Dr. H. Reid
    33 questions
    Skin Tumors: Seborrheic Keratosis Overview
    8 questions
    Use Quizgecko on...
    Browser
    Browser