Nonmelanocytic Malignant Skin Tumors Quiz
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Questions and Answers

Which of the following is NOT a risk factor for Basal Cell Carcinoma?

  • Acidic diet (correct)
  • Gene mutations
  • UV exposure
  • Arsenic exposure

What is the main function of Hedgehog proteins?

  • Prevent UV radiation damage
  • Regulate cell proliferation and differentiation (correct)
  • Increase elastin production in the skin
  • Cause direct DNA damage

Which type of UV radiation is most absorbed by the epidermis and is considered the most carcinogenic?

  • UV-A
  • UV-B (correct)
  • UV-D
  • UV-C

What gene mutation is associated with the development of Basal Cell Carcinoma?

<p>PTCH gene mutation (A)</p> Signup and view all the answers

Which of the following is a microscopic feature of Basal Cell Carcinoma?

<p>Nodules in the dermis (C)</p> Signup and view all the answers

What is the main function of UV radiation in skin tumor development?

<p>Induce p53 mutation (D)</p> Signup and view all the answers

Which type of skin tumor may present with cutaneous horn?

<p>Actinic keratosis (D)</p> Signup and view all the answers

What is considered the primary complete carcinogen related to skin tumors?

<p>UV radiation (B)</p> Signup and view all the answers

Which of the following tumors is NOT associated with nevoid basal cell carcinoma syndrome?

<p>Squamous cell carcinoma in the skin (B)</p> Signup and view all the answers

Which of the following tumors is most commonly associated with Merkel cell carcinoma?

<p>Melanoma (C)</p> Signup and view all the answers

What is a common risk factor for squamous cell carcinoma?

<p>UV exposure (C)</p> Signup and view all the answers

Which of the following microscopic features is characteristic of Merkel cell carcinoma?

<p>Round and vesicular nuclei (B)</p> Signup and view all the answers

What is one of the clinical presentations of Merkel cell carcinoma?

<p>Painless nodules (A)</p> Signup and view all the answers

Which microscopic feature is indicative of Acantholytic Squamous Cell Carcinoma?

<p>Loss of intercellular connection (A)</p> Signup and view all the answers

What feature distinguishes Squamous Cell Carcinoma in situ from invasive SCC under a microscope?

<p>No dermal invasion (C)</p> Signup and view all the answers

What is a characteristic histological pattern of Squamous Cell Carcinoma?

<p>Verrucous (A)</p> Signup and view all the answers

What is the most common type of cutaneous T cell lymphoma described in the text?

<p>Mycosis Fungoides (A)</p> Signup and view all the answers

Which type of lymphoma is CD45+?

<p>Lymphoma (D)</p> Signup and view all the answers

What microscopic feature is associated with the 'Patch' stage of Mycosis Fungoides?

<p>Clustered in epidermis (C)</p> Signup and view all the answers

Which syndrome is commonly associated with erythroderma and lymphadenopathy?

<p>Sézary syndrome (C)</p> Signup and view all the answers

What type of cells are positive for CD4 and negative for CD8 in Sézary syndrome?

<p>Neoplastic T cells w cerebriform nuclei (Sézary cells) (C)</p> Signup and view all the answers

Which stage of Mycosis Fungoides may resemble psoriasis?

<p>Plaque stage (B)</p> Signup and view all the answers

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