Nonmelanocytic Malignant Skin Tumors Quiz
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Questions and Answers

Which of the following is NOT a risk factor for Basal Cell Carcinoma?

  • Acidic diet (correct)
  • Gene mutations
  • UV exposure
  • Arsenic exposure

    • What is the main function of Hedgehog proteins?

  • Prevent UV radiation damage
  • Regulate cell proliferation and differentiation (correct)
  • Increase elastin production in the skin
  • Cause direct DNA damage

    • Which type of UV radiation is most absorbed by the epidermis and is considered the most carcinogenic?

  • UV-A
  • UV-B (correct)
  • UV-D
  • UV-C

    • What gene mutation is associated with the development of Basal Cell Carcinoma?

    <p>PTCH gene mutation</p> Signup and view all the answers

    Which of the following is a microscopic feature of Basal Cell Carcinoma?

    <p>Nodules in the dermis</p> Signup and view all the answers

    What is the main function of UV radiation in skin tumor development?

    <p>Induce p53 mutation</p> Signup and view all the answers

    Which type of skin tumor may present with cutaneous horn?

    <p>Actinic keratosis</p> Signup and view all the answers

    What is considered the primary complete carcinogen related to skin tumors?

    <p>UV radiation</p> Signup and view all the answers

    Which of the following tumors is NOT associated with nevoid basal cell carcinoma syndrome?

    <p>Squamous cell carcinoma in the skin</p> Signup and view all the answers

    Which of the following tumors is most commonly associated with Merkel cell carcinoma?

    <p>Melanoma</p> Signup and view all the answers

    What is a common risk factor for squamous cell carcinoma?

    <p>UV exposure</p> Signup and view all the answers

    Which of the following microscopic features is characteristic of Merkel cell carcinoma?

    <p>Round and vesicular nuclei</p> Signup and view all the answers

    What is one of the clinical presentations of Merkel cell carcinoma?

    <p>Painless nodules</p> Signup and view all the answers

    Which microscopic feature is indicative of Acantholytic Squamous Cell Carcinoma?

    <p>Loss of intercellular connection</p> Signup and view all the answers

    What feature distinguishes Squamous Cell Carcinoma in situ from invasive SCC under a microscope?

    <p>No dermal invasion</p> Signup and view all the answers

    What is a characteristic histological pattern of Squamous Cell Carcinoma?

    <p>Verrucous</p> Signup and view all the answers

    What is the most common type of cutaneous T cell lymphoma described in the text?

    <p>Mycosis Fungoides</p> Signup and view all the answers

    Which type of lymphoma is CD45+?

    <p>Lymphoma</p> Signup and view all the answers

    What microscopic feature is associated with the 'Patch' stage of Mycosis Fungoides?

    <p>Clustered in epidermis</p> Signup and view all the answers

    Which syndrome is commonly associated with erythroderma and lymphadenopathy?

    <p>Sézary syndrome</p> Signup and view all the answers

    What type of cells are positive for CD4 and negative for CD8 in Sézary syndrome?

    <p>Neoplastic T cells w cerebriform nuclei (Sézary cells)</p> Signup and view all the answers

    Which stage of Mycosis Fungoides may resemble psoriasis?

    <p>Plaque stage</p> Signup and view all the answers

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