Podcast
Questions and Answers
Which of the following is NOT a typical secretion of the stomach?
Which of the following is NOT a typical secretion of the stomach?
- Hydrochloric acid
- Bicarbonate
- Amylase (correct)
- Intrinsic factor
Parietal cells in the gastric gland are primarily responsible for producing which substance?
Parietal cells in the gastric gland are primarily responsible for producing which substance?
- Pepsinogen
- Hydrochloric acid (correct)
- Mucus
- Gastrin
Which of the following factors can stimulate the secretion of hydrochloric acid (HCl) by parietal cells?
Which of the following factors can stimulate the secretion of hydrochloric acid (HCl) by parietal cells?
- Large fatty meals
- Emotional stress
- Caffeine
- All of the above (correct)
What is the primary function of mucus secreted by the gastric mucosa?
What is the primary function of mucus secreted by the gastric mucosa?
Which of the following conditions is NOT directly related to acid production in the stomach?
Which of the following conditions is NOT directly related to acid production in the stomach?
What is the primary mechanism of action of antacids?
What is the primary mechanism of action of antacids?
Which of the following best describes how antacids promote gastric mucosal defense?
Which of the following best describes how antacids promote gastric mucosal defense?
Which of the following is a potential adverse effect associated with aluminum-containing antacids?
Which of the following is a potential adverse effect associated with aluminum-containing antacids?
Why are magnesium-containing antacids often combined with aluminum-containing antacids?
Why are magnesium-containing antacids often combined with aluminum-containing antacids?
A patient with a history of renal failure is prescribed an antacid. Which type of antacid should be avoided?
A patient with a history of renal failure is prescribed an antacid. Which type of antacid should be avoided?
What is a potential consequence of long-term use of calcium-based antacids?
What is a potential consequence of long-term use of calcium-based antacids?
Which of the following is a characteristic of sodium bicarbonate antacids?
Which of the following is a characteristic of sodium bicarbonate antacids?
Why should caution be used when administering sodium bicarbonate antacids to patients with heart failure?
Why should caution be used when administering sodium bicarbonate antacids to patients with heart failure?
How should enteric-coated medications be taken in relation to antacids?
How should enteric-coated medications be taken in relation to antacids?
What is a primary mechanism of action of H2 receptor antagonists?
What is a primary mechanism of action of H2 receptor antagonists?
Which suffix is commonly found in the generic names of H2 receptor antagonists?
Which suffix is commonly found in the generic names of H2 receptor antagonists?
Which of the following statements regarding H2 receptor antagonists is correct?
Which of the following statements regarding H2 receptor antagonists is correct?
In which clinical situation would H2 receptor antagonists be most appropriate?
In which clinical situation would H2 receptor antagonists be most appropriate?
Which of the following adverse effects is more commonly associated with cimetidine compared to other H2 receptor antagonists?
Which of the following adverse effects is more commonly associated with cimetidine compared to other H2 receptor antagonists?
How does cimetidine interact with the cytochrome P450 enzyme system?
How does cimetidine interact with the cytochrome P450 enzyme system?
Which of the following instructions should the nurse include when teaching a patient about taking H2 receptor antagonists?
Which of the following instructions should the nurse include when teaching a patient about taking H2 receptor antagonists?
Smoking decreases the effectiveness of which of the following medications?
Smoking decreases the effectiveness of which of the following medications?
What laboratory values should a nurse assess in patients with impaired renal or liver function before administering H2 receptor antagonists?
What laboratory values should a nurse assess in patients with impaired renal or liver function before administering H2 receptor antagonists?
What is the mechanism of action of proton pump inhibitors (PPIs)?
What is the mechanism of action of proton pump inhibitors (PPIs)?
Which suffix is characteristic of proton pump inhibitors (PPIs)?
Which suffix is characteristic of proton pump inhibitors (PPIs)?
For which condition are proton pump inhibitors (PPIs) typically considered a first-line therapy?
For which condition are proton pump inhibitors (PPIs) typically considered a first-line therapy?
Which of the following is a potential long-term adverse effect of proton pump inhibitors (PPIs)?
Which of the following is a potential long-term adverse effect of proton pump inhibitors (PPIs)?
How do proton pump inhibitors (PPIs) affect the absorption of ketoconazole, ampicillin, and iron salts?
How do proton pump inhibitors (PPIs) affect the absorption of ketoconazole, ampicillin, and iron salts?
When should omeprazole (Losec) be administered in relation to meals?
When should omeprazole (Losec) be administered in relation to meals?
What is a key instruction that the nurse should provide to a patient taking pantoprazole capsules via a gastric tube?
What is a key instruction that the nurse should provide to a patient taking pantoprazole capsules via a gastric tube?
What is the primary mechanism of action of sucralfate in treating ulcers?
What is the primary mechanism of action of sucralfate in treating ulcers?
What is an important consideration when administering sucralfate with other medications?
What is an important consideration when administering sucralfate with other medications?
Why is misoprostol contraindicated in pregnant women?
Why is misoprostol contraindicated in pregnant women?
What is the mechanism of action of simethicone?
What is the mechanism of action of simethicone?
Patients with a history of what condition should be most cautious when using bismuth subsalicylate?
Patients with a history of what condition should be most cautious when using bismuth subsalicylate?
What is the primary mechanism of action of anticholinergic antidiarrheal medications?
What is the primary mechanism of action of anticholinergic antidiarrheal medications?
Which potential side effect should patients be aware of when taking anticholinergic antidiarrheal medications?
Which potential side effect should patients be aware of when taking anticholinergic antidiarrheal medications?
What is the primary effect of opiate antidiarrheal medications on bowel function?
What is the primary effect of opiate antidiarrheal medications on bowel function?
Which potential side effect is most important to monitor in patients taking opiate antidiarrheal medications in conjunction with other CNS-depressant medications?
Which potential side effect is most important to monitor in patients taking opiate antidiarrheal medications in conjunction with other CNS-depressant medications?
What is the general mechanism of action of adsorbent antidiarrheals?
What is the general mechanism of action of adsorbent antidiarrheals?
What is the intended action of probiotic antidiarrheal medications?
What is the intended action of probiotic antidiarrheal medications?
Which instruction is most important for the nurse to give patients taking any form of antidiarrheal medications?
Which instruction is most important for the nurse to give patients taking any form of antidiarrheal medications?
What is the most appropriate initial nursing action before administering a laxative to a patient?
What is the most appropriate initial nursing action before administering a laxative to a patient?
Why might a healthcare provider advise a patient like Jerry, who has been self-treating heartburn with antacids, to discontinue their use prior to further evaluation?
Why might a healthcare provider advise a patient like Jerry, who has been self-treating heartburn with antacids, to discontinue their use prior to further evaluation?
In the case of a patient with GERD and gastritis secondary to stress-induced hyperacidity, what is the primary rationale for using PPIs like omeprazole?
In the case of a patient with GERD and gastritis secondary to stress-induced hyperacidity, what is the primary rationale for using PPIs like omeprazole?
What key information should be included when educating a patient, such as Jerry, who is starting PPI therapy for GERD?
What key information should be included when educating a patient, such as Jerry, who is starting PPI therapy for GERD?
Which question would be most important for the nurse to ask Petra, an elderly patient reporting chronic constipation and stimulant laxative use, to assess potential contributing factors?
Which question would be most important for the nurse to ask Petra, an elderly patient reporting chronic constipation and stimulant laxative use, to assess potential contributing factors?
What is a potential long-term consequence associated with chronic use of stimulant laxatives, such as those being used by Petra?
What is a potential long-term consequence associated with chronic use of stimulant laxatives, such as those being used by Petra?
Which nonpharmacological intervention would be most appropriate for Petra to prevent constipation?
Which nonpharmacological intervention would be most appropriate for Petra to prevent constipation?
Considering Petra's age and history of chronic stimulant laxative use, which over-the-counter (OTC) option would be the most appropriate first-line choice to help prevent constipation?
Considering Petra's age and history of chronic stimulant laxative use, which over-the-counter (OTC) option would be the most appropriate first-line choice to help prevent constipation?
What is the primary mechanism of action of ondansetron (Zofran) in managing chemotherapy-induced nausea and vomiting for patients like Mr. Lee Edwards?
What is the primary mechanism of action of ondansetron (Zofran) in managing chemotherapy-induced nausea and vomiting for patients like Mr. Lee Edwards?
Which important teaching point should the nurse emphasize to Mr. Lee Edwards regarding his oral ondansetron prescription?
Which important teaching point should the nurse emphasize to Mr. Lee Edwards regarding his oral ondansetron prescription?
If Mr. Lee reports that ondansetron is not effectively controlling his chemotherapy-induced nausea and vomiting, and expresses concern about a friend's suggestion to use marijuana, what would be the most appropriate initial response?
If Mr. Lee reports that ondansetron is not effectively controlling his chemotherapy-induced nausea and vomiting, and expresses concern about a friend's suggestion to use marijuana, what would be the most appropriate initial response?
Flashcards
Hydrochloric acid (HCl)
Hydrochloric acid (HCl)
Produced by parietal gland; aids digestion & barrier to infection.
Bicarbonate in stomach
Bicarbonate in stomach
Buffers stomach acid, preventing hyperacidity.
Pepsinogen precursor
Pepsinogen precursor
Needed for dietary protein breakdown in the stomach.
Intrinsic factor
Intrinsic factor
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Mucous in stomach
Mucous in stomach
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Prostaglandins (PG's)
Prostaglandins (PG's)
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Parietal cells
Parietal cells
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Most common acid-related disease
Most common acid-related disease
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PUD: peptic ulcer disease
PUD: peptic ulcer disease
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GERD: acid reflux disease
GERD: acid reflux disease
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Helicobacter pylori (H. pylori)
Helicobacter pylori (H. pylori)
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Antacids
Antacids
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H2 antagonists
H2 antagonists
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Proton pump inhibitors PPIs
Proton pump inhibitors PPIs
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Antacids Indications
Antacids Indications
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Antacids: Aluminum Salts
Antacids: Aluminum Salts
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Antacids: Magnesium Salts
Antacids: Magnesium Salts
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Antacids: Calcium Salts
Antacids: Calcium Salts
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Antacids: Sodium Bicarbonate
Antacids: Sodium Bicarbonate
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H2 receptor antagonists
H2 receptor antagonists
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H2 Receptor Antagonists Action
H2 Receptor Antagonists Action
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Parietal cell stimulation
Parietal cell stimulation
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PPIs
PPIs
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Lansoprazole (Prevacid)
Lansoprazole (Prevacid)
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Sucralfate
Sucralfate
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Simethicone
Simethicone
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Diarrhea
Diarrhea
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Adsorbents
Adsorbents
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Anticholinergics
Anticholinergics
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Opiates
Opiates
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Probiotics
Probiotics
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Bulk forming
Bulk forming
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Emollient
Emollient
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Hyperosmotic
Hyperosmotic
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Stimulant
Stimulant
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Nausea
Nausea
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Emesis (vomitting)
Emesis (vomitting)
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Antiemetic agents
Antiemetic agents
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Vomiting center (VC)
Vomiting center (VC)
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Why stop antacids before tests?
Why stop antacids before tests?
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Rationale for PPI use in GERD
Rationale for PPI use in GERD
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Risks of long-term laxative use
Risks of long-term laxative use
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Nonpharmacological constipation prevention
Nonpharmacological constipation prevention
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Ondansetron mechanism of action
Ondansetron mechanism of action
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Patient teaching for ondansetron
Patient teaching for ondansetron
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Study Notes
Case Study Chapter 39: Acid Controlling Drugs
- Mr. Jerry Yip, a 50-year-old attorney, self-treated heartburn for years with large amounts of antacids.
- His healthcare provider instructed him to stop taking antacids and referred him to a gastroenterologist after discovery of GERD (gastroesophageal reflux disease) and gastritis secondary to stress-induced hyperacidity via endoscopy.
- The healthcare provider prescribed omeprazole (Prilosec, Losec) 20 mg once daily.
Case Study Chapter 40: Antidiarrheal Drugs and Laxatives
- Petra, a 72-year-old retired nurse who exercises regularly, reports constipation with only one bowel movement every 3 days for the past 3 months, instead of daily.
- Petra has been taking a stimulant laxative up to twice a day and feels weak and has tummy cramping.
Case Study Chapter 41: Antiemetic and Antinausea Drugs
- Mr. Lee Edwards, a 66-year-old carpenter with a recent lung cancer diagnosis, starts chemotherapy after recovering from a right lung lobectomy.
- His premedication includes various drugs, including oral ondansetron (Zofran) for home use.
- Key considerations include the mechanism of action of ondansetron (Zofran) for chemotherapy-induced nausea and vomiting, patient teaching points, and what to explain if ondansetron is ineffective and marijuana is suggested.
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