3 Questions
Which protein anchors thick filaments to Z lines in skeletal muscle?
Titin
Which protein bundles thin filaments into parallel arrays and helps anchor them at the Z line in skeletal muscle?
Alpha-actinin
Which protein holds thick filaments in register at the M line in skeletal muscle?
Myomesin
Test your knowledge on accessory proteins in skeletal muscle and their role in sarcomere function. Learn about the functions of titin and alpha-actinin and their importance in stabilizing and preventing excessive stretching of the sarcomere. Plus, discover how a mutation in the TTN gene encoding titin can lead to dilated cardiomyopathy.
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