Podcast
Questions and Answers
Which characteristic of the Vaccinia virus genome is mentioned in the text?
Which characteristic of the Vaccinia virus genome is mentioned in the text?
- Circular, single-stranded DNA
- Linear, single-stranded RNA
- Linear, double-stranded DNA (correct)
- Circular, double-stranded RNA
What is the primary location for replication of the Vaccinia virus within the host cell?
What is the primary location for replication of the Vaccinia virus within the host cell?
- Cytoplasm (correct)
- Nucleus
- Endoplasmic reticulum
- Mitochondria
Which of the following diseases is caused by the Variola virus?
Which of the following diseases is caused by the Variola virus?
- Rubella
- Chickenpox
- Measles
- Smallpox (correct)
What is the primary characteristic that differentiates Poxviridae from other viruses?
What is the primary characteristic that differentiates Poxviridae from other viruses?
In AAV vectors, what is the significance of Inverted Terminal Repeats (ITRs)?
In AAV vectors, what is the significance of Inverted Terminal Repeats (ITRs)?
What is the primary humoral immune response responsible for regarding AAV vectors?
What is the primary humoral immune response responsible for regarding AAV vectors?
Which chromosome does the adeno-associated virus (AAV) genome integrate into during site-specific integration?
Which chromosome does the adeno-associated virus (AAV) genome integrate into during site-specific integration?
What are the sequences at the ends of the AAV genome called, and what is their function?
What are the sequences at the ends of the AAV genome called, and what is their function?
What are the two open reading frames (ORFs) present in the AAV genome, and what are their functions?
What are the two open reading frames (ORFs) present in the AAV genome, and what are their functions?
What is the primary difference between recombinant AAV (rAAV) vectors and self-complementary (scAAV) recombinant vectors?
What is the primary difference between recombinant AAV (rAAV) vectors and self-complementary (scAAV) recombinant vectors?
What is the primary function of the Rep gene in the AAV genome?
What is the primary function of the Rep gene in the AAV genome?
How are the positive (+) and negative (-) strands of the AAV genome packaged into the viral capsid?
How are the positive (+) and negative (-) strands of the AAV genome packaged into the viral capsid?
