Podcast
Questions and Answers
What is the first-line antibiotic for treating a dental abscess?
What is the first-line antibiotic for treating a dental abscess?
Which antibiotic is preferred for dental abscesses in patients with penicillin allergy?
Which antibiotic is preferred for dental abscesses in patients with penicillin allergy?
What is the most common gram-negative pathogen in intra-abdominal infections?
What is the most common gram-negative pathogen in intra-abdominal infections?
Which anaerobic pathogen is most commonly associated with intra-abdominal infections?
Which anaerobic pathogen is most commonly associated with intra-abdominal infections?
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What is the preferred empiric treatment for low-risk community-acquired intra-abdominal infections?
What is the preferred empiric treatment for low-risk community-acquired intra-abdominal infections?
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Which antibiotic class is commonly used for high-risk community-acquired intra-abdominal infections?
Which antibiotic class is commonly used for high-risk community-acquired intra-abdominal infections?
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Which gram-positive anaerobic pathogen is often implicated in intra-abdominal infections?
Which gram-positive anaerobic pathogen is often implicated in intra-abdominal infections?
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Which antibiotic is most strongly associated with a high risk of C. difficile infection?
Which antibiotic is most strongly associated with a high risk of C. difficile infection?
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What is the first-line treatment for a first-time outpatient case of C. difficile colitis?
What is the first-line treatment for a first-time outpatient case of C. difficile colitis?
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How does fidaxomicin work in C. difficile infections?
How does fidaxomicin work in C. difficile infections?
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Which antibiotic should be avoided in pregnancy for intra-abdominal infections?
Which antibiotic should be avoided in pregnancy for intra-abdominal infections?
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What clinical sign distinguishes C. difficile colitis from antibiotic-associated diarrhea?
What clinical sign distinguishes C. difficile colitis from antibiotic-associated diarrhea?
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What is the preferred empiric antibiotic for a health care-associated intra-abdominal infection?
What is the preferred empiric antibiotic for a health care-associated intra-abdominal infection?
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Study Notes
Antibiotic Treatment for Dental Abscesses and Intra-abdominal Infections
- Dental Abscess First-Line: Amoxicillin
- Penicillin Allergy: Clindamycin is preferred alternative
- Intra-abdominal Infection Common Pathogen: Escherichia coli
- Intra-abdominal Infection Common Anaerobic Pathogen: Bacteroides fragilis
Low-Risk Community-Acquired Intra-abdominal Infections
- Preferred Empiric Treatment: Ceftriaxone with metronidazole
High-Risk Community-Acquired Intra-abdominal Infections
- Common Antibiotic Class: Carbapenems
Gram-Positive Anaerobic Pathogens in Intra-abdominal Infections
- Common Pathogen: Peptostreptococcus species
Antibiotic Associated with High Risk of C. difficile Infection
- Antibiotic: Clindamycin
First-Line Treatment for C. difficile Colitis (Outpatient)
- Treatment: Oral Vancomycin
Fidaxomicin Mechanism of Action
- Mechanism of Action: Inhibits bacterial RNA polymerase
Antibiotic Contraindicated in Pregnancy
- Antibiotic: Ciprofloxacin
Clincal Sign Distinguishing C. difficile Colitis from Antibiotic-associated Diarrhea
- Distinguishing Sign: Strong, foul-smelling diarrhea
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