Pharm GI Antibiotics Quiz PDF

1. What is the first-line antibiotic for treating a dental abscess? a) Ciprofloxacin b) Amoxicillin c) Metronidazole d) Azithromycin Answer: b) Amoxicillin 2. Which antibiotic is preferred for dental abscesses in patients with penicillin allergy? a) Clindamycin b) Piperacillin-tazobactam c) Ceftriax...

1. What is the first-line antibiotic for treating a dental abscess? a) Ciprofloxacin b) Amoxicillin c) Metronidazole d) Azithromycin Answer: b) Amoxicillin 2. Which antibiotic is preferred for dental abscesses in patients with penicillin allergy? a) Clindamycin b) Piperacillin-tazobactam c) Ceftriaxone d) Amoxicillin-clavulanate Answer: a) Clindamycin 3. What is the most common gram-negative pathogen in intra-abdominal infections? a) Klebsiella species b) Proteus species c) Escherichia coli d) Pseudomonas aeruginosa Answer: c) Escherichia coli 4. Which anaerobic pathogen is most commonly associated with intra-abdominal infections? a) Clostridium species b) Bacteroides fragilis c) Peptostreptococcus species d) Fusobacterium species Answer: b) Bacteroides fragilis 5. What is the preferred empiric treatment for low-risk community-acquired intra-abdominal infections? a) Piperacillin-tazobactam b) Meropenem c) Ceftriaxone with metronidazole d) Vancomycin Answer: c) Ceftriaxone with metronidazole 6. Which antibiotic class is commonly used for high-risk community-acquired intra-abdominal infections? a) Carbapenems b) Macrolides c) Sulfonamides d) Cephalosporins without metronidazole Answer: a) Carbapenems 7. Which gram-positive anaerobic pathogen is often implicated in intra-abdominal infections? a) Fusobacterium species b) Peptostreptococcus species c) Clostridium difficile d) Prevotella species Answer: b) Peptostreptococcus species 8. Which antibiotic is most strongly associated with a high risk of C. difficile infection? a) Clindamycin b) Doxycycline c) Azithromycin d) Amoxicillin Answer: a) Clindamycin 9. What is the first-line treatment for a first-time outpatient case of C. difficile colitis? a) IV Vancomycin b) Oral Vancomycin c) Metronidazole d) Fidaxomicin Answer: d) Fidaxomicin 10. How does fidaxomicin work in C. difficile infections? a) Inhibits bacterial RNA polymerase b) Blocks DNA gyrase c) Disrupts bacterial cell walls d) Binds to 30S ribosomal subunits Answer: a) Inhibits bacterial RNA polymerase 11. Which antibiotic should be avoided in pregnancy for intra-abdominal infections? a) Amoxicillin b) Metronidazole c) Ciprofloxacin d) Piperacillin-tazobactam Answer: c) Ciprofloxacin 12. What clinical sign distinguishes C. difficile colitis from antibiotic-associated diarrhea? a) Watery stools b) Strong, foul-smelling diarrhea c) Diarrhea resolving with cessation of antibiotics d) Abdominal distension Answer: b) Strong, foul-smelling diarrhea 13. What is the preferred empiric antibiotic for a health care-associated intra-abdominal infection? a) Ciprofloxacin with metronidazole b) Piperacillin-tazobactam c) Ceftriaxone with vancomycin d) Clindamycin Answer: b) Piperacillin-tazobactam