Bone Physiology

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Questions and Answers

What forms the outer surfaces of compact bone?

  • Compact bone matrix
  • Hyaline cartilage
  • Circumferential lamellae (correct)
  • Trabecular network

When does intramembranous ossification begin during embryonic development?

  • Eighth week (correct)
  • Twelfth week
  • Fifteenth week
  • Fourth week

Which type of cells specialize to become osteoblasts in intramembranous ossification?

  • Osteocytes
  • Mesenchymal cells (correct)
  • Chondroblasts
  • Fibroblasts

What is formed as a result of the joining of trabeculae in intramembranous ossification?

<p>Spongy bone (D)</p> Signup and view all the answers

What is the role of osteoblasts in the process of intramembranous ossification?

<p>Produce bone matrix (D)</p> Signup and view all the answers

What is the primary purpose of chondroblasts during endochondral ossification?

<p>To create a cartilage model (B)</p> Signup and view all the answers

At what age does endochondral ossification typically complete?

<p>18–20 years (A)</p> Signup and view all the answers

Which cells are responsible for forming red bone marrow as trabeculae join together in intramembranous ossification?

<p>Cells within the spaces of spongy bone (C)</p> Signup and view all the answers

What type of cartilage growth involves the addition of new cartilage matrix at the outer edge of existing cartilage?

<p>Appositional growth (D)</p> Signup and view all the answers

What primarily constitutes the organic component of the bone matrix?

<p>Collagen and proteoglycans (B)</p> Signup and view all the answers

Which type of bone cell is responsible for breaking down the bone matrix?

<p>Osteoclasts (C)</p> Signup and view all the answers

How does spongy bone differ from compact bone?

<p>Spongy bone consists of trabeculae with more interconnecting rods. (B)</p> Signup and view all the answers

What role do osteoblasts play in bone tissue?

<p>They form new bone. (C)</p> Signup and view all the answers

What is the primary inorganic component of the bone matrix?

<p>Hydroxyapatite (D)</p> Signup and view all the answers

Which statement best describes the role of canaliculi in spongy bone?

<p>They connect osteocytes for communication. (B)</p> Signup and view all the answers

What characteristic feature distinguishes the lamellae in compact bone?

<p>Concentric arrangement (C)</p> Signup and view all the answers

What is the primary ossification center in long bones?

<p>Diaphysis (B)</p> Signup and view all the answers

At what age does the last secondary ossification center typically appear?

<p>18-20 years (A)</p> Signup and view all the answers

What happens to the epiphyseal plate after a person’s bones have stopped growing?

<p>It regresses into an epiphyseal line (C)</p> Signup and view all the answers

Which type of bone fracture involves a break that does not penetrate the skin?

<p>Closed (simple) fracture (B)</p> Signup and view all the answers

Which of the following is a characteristic of the articular cartilage?

<p>It is derived from embryonic cartilage and remains throughout life (A)</p> Signup and view all the answers

Where do secondary ossification centers typically appear before birth?

<p>In the epiphyses of the femur, humerus, and tibia (C)</p> Signup and view all the answers

Which statement accurately describes the spongy and compact bone in mature bones?

<p>Both are fully developed, and the epiphyseal plate has turned into the epiphyseal line (C)</p> Signup and view all the answers

What treatment is commonly used for bone fractures?

<p>Reduction and immobilization (A)</p> Signup and view all the answers

What happens to the perichondrium during the process of endochondral ossification?

<p>It transforms into the periosteum. (C)</p> Signup and view all the answers

What contributes to the increase in size of the cartilage model during endochondral ossification?

<p>Both interstitial and appositional cartilage growth. (D)</p> Signup and view all the answers

What is the substance that chondrocytes release to initiate the formation of hydroxyapatite crystals?

<p>Matrix vesicles. (C)</p> Signup and view all the answers

What occurs in the primary ossification center during endochondral ossification?

<p>Osteoblasts produce bone on the surface of calcified cartilage. (C)</p> Signup and view all the answers

What structural change occurs to the bone as it develops during endochondral ossification?

<p>Woven bone is converted to lamellar bone. (A)</p> Signup and view all the answers

What is the fate of chondrocytes in the calcified cartilage area during endochondral ossification?

<p>They die and leave enlarged lacunae. (C)</p> Signup and view all the answers

Which cells migrate into the calcified cartilage area from the periosteum during ossification?

<p>Osteoblasts and osteoclasts. (A)</p> Signup and view all the answers

What role do osteoclasts play in endochondral ossification?

<p>They remove bone from the center of the diaphysis. (D)</p> Signup and view all the answers

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