Week 12 Multiple Choice Questions PDF
Document Details
Uploaded by mandystudies
University of Toronto
Tags
Summary
This document contains multiple choice questions on various aspects of cancer biology. The questions cover topics such as different forms of neoplasms, metastasis, types of cancers, cellular processes, and characteristics of cancerous vs non-cancerous tissues.
Full Transcript
**[Week 12 ]** **Multiple Choice Questions** 1. What is another term for neoplasm? - **a) Tumor** - b\) Cancer - c\) Cyst - d\) Lesion 2. Which of the following is a characteristic of a benign tumor? - a\) Can metastasize - b\) Grows fast - **c)...
**[Week 12 ]** **Multiple Choice Questions** 1. What is another term for neoplasm? - **a) Tumor** - b\) Cancer - c\) Cyst - d\) Lesion 2. Which of the following is a characteristic of a benign tumor? - a\) Can metastasize - b\) Grows fast - **c) Not cancerous** - d\) Invades nearby tissues 3. What is the main site of metastasis for breast cancer? - a\) Liver, lungs, peritoneum - b\) Bones, skin/muscle, liver - **c) Lungs, liver, bones** - d\) Peritoneum, liver, lungs 4. Which cancer type commonly metastasizes to the adrenal gland? - a\) Colon - **b) Lung** - c\) Prostate - d\) Melanoma 5. What is the term for the spread of cancer from one part of the body to another? - a\) Angiogenesis - b\) Apoptosis - **c) Metastasis** - d\) Invasion 6. Which type of cancer originates in supportive and connective tissues? - a\) Carcinoma - b\) **Sarcoma** - c\) Leukemia - d\) Lymphoma 7. What is the primary site for a secondary cancer? - a\) The original site where cancer started - b\) A new, independent site - **c) The same type of cells as the primary site** - d\) None of the above 8. Which subtype of carcinoma develops in an organ or gland? - a\) Squamous cell carcinoma - **b) Adenocarcinoma** - c\) Osteosarcoma - d\) Liposarcoma 9. What is the most common first sign of retinoblastoma? - a\) Red eye - **b) Cat's eye reflex (leukocoria)** - c\) Blurred vision - d\) Eye pain 10. What is the function of tumor suppressor genes? - a\) Promote cell division - **b) Inhibit cell division and survival** - c\) Mutate into oncogenes - d\) None of the above 11. What is the term for programmed cell death? - a\) Angiogenesis - **b) Apoptosis** - c\) Metastasis - d\) Proliferation 12. Which cancer type is associated with the overproduction of immature white blood cells? - a\) Carcinoma - b\) Sarcoma - **c) Leukemia** - d\) Lymphoma 13. What is the TNM staging system used for? - a\) Classifying tumor cells based on appearance - **b) Determining the extent of cancer in the body** - c\) Identifying genetic mutations - d\) Assessing patient survival rates 14. What does T3 N2 M0 indicate in cancer staging? - a\) Small tumor, no lymph node involvement, no metastasis - **b) Large tumor, lymph node involvement, no metastasis** - c\) Large tumor, no lymph node involvement, metastasis present - d\) Small tumor, lymph node involvement, metastasis present 15. Which stage of cancer is characterized by localized spread? - a\) Stage 0 - **b) Stage I & II** - c\) Stage III - d\) Stage IV 16. What is the primary function of angiogenesis in cancer? - a\) Cell death - **b) Blood vessel formation** - c\) Cell division - d\) Metastasis 17. Which cancer type develops in the glands or nodes of the lymphatic system? - a\) Carcinoma - b\) Sarcoma - c\) Leukemia - **d) Lymphoma** 18. What is the main characteristic of a poorly differentiated tumor? - a\) Cells look normal and grow slowly - **b) Cells look abnormal and grow quickly** - c\) Cells are well differentiated - d\) None of the above 19. Which cancer type is associated with the TP53 tumor suppressor gene mutation? - a\) Retinoblastoma - **b) Li-Fraumeni Syndrome** - c\) Familial Adenomatous Polyposis - d\) None of the above 20. What is the primary site of metastasis for prostate cancer? - a\) Liver, peritoneum, lungs - **b) Bones, lungs, liver** - c\) Lungs, liver, adrenal gland - d\) none of the above 21. What is the term for a tumor that has not yet become malignant but is about to? - a\) Benign tumor - **b) Pre-malignant tumor** - c\) Malignant tumor - d\) None of the above 22. What is the main site of metastasis for melanoma? - a\) Liver, peritoneum, lungs - b\) Bones, muscle, lungs - c\) Skin/muscle, adrenal gland, liver - **d) Lungs, skin/muscle, liver** 23. What is the main characteristic of a carcinoma? - a\) Originates in supportive and connective tissues - **b) Malignant neoplasm of epithelial origin** - c\) Originates in the plasma cells of bone marrow - d\) Develops in the glands or nodes of the lymphatic system 24. What is the primary function of proto-oncogenes? - **a) Control how often a cell divides** - b\) Inhibit cell division and survival - c\) Promote cell death - d\) None of the above 25. What is the main site of metastasis for colon cancer? - **a) Liver, peritoneum, lungs** - b\) Bones, liver, lungs - c\) Lungs, skin/muscle, liver - d\) Peritoneum, liver, adrenal gland 26. What is the main characteristic of a well-differentiated tumor? - **a) Cells look normal and grow slowly** - b\) Cells look abnormal and grow quickly - c\) Cells are poorly differentiated - d\) None of the above 27. What is the main site of metastasis for kidney cancer? - a\) Liver - b\) Bones - c\) Lungs - **d) All of the above** 28. What is the primary function of the APC gene? - a\) Promote cell division - **b) Inhibit cell division and survival** - c\) Control how often a cell divides - d\) None of the above 29. What is the main site of metastasis for ovarian cancer? - a\) Liver, lungs, skin - b\) Bones, liver, lungs - c\) Lungs, bones, adrenal gland - **d) Peritoneum, liver lungs** 30. What is the main characteristic of a mixed mesodermal tumor? - a\) Originates in supportive and connective tissues - **b) Contains components from different categories** - c\) Develops in the glands or nodes of the lymphatic system - d\) None of the above 31. What is the main site of metastasis for pancreatic cancer? - **a) Liver, lungs peritoneum** - b\) Bones, liver, lungs - c\) Lungs, skin/muscle, liver - d\) Peritoneum, adrenal gland, liver 32. What is the main characteristic of a carcinoma in situ? - **a) Abnormal cells are present but have not spread to neighboring tissue** - b\) Cells look abnormal and grow quickly - c\) Cells are well differentiated - d\) None of the above 33. What is the main site of metastasis for rectal cancer? - **a) Liver, lungs, adrenal gland** - b\) Bones, lungs liver, - c\) Lungs, liver, peritoneum - d\) Adrenal gland, peritoneum, bones 34. What does the \"T\" in TNM staging stand for? - **a) Tumor size and extent** - b\) Tumor grade - c\) Tumor location - d\) Tumor type 35. What does \"N1\" indicate in the TNM staging system? - a\) No regional lymph node involvement - b\) Regional lymph nodes cannot be assessed - **c) Regional lymph node involvement** - d\) Distant metastasis 36. What does \"M0\" indicate in the TNM staging system? - **a) No distant metastasis** - b\) Distant metastasis present - c\) Regional lymph node involvement - d\) Primary tumor cannot be assessed 37. Which grade indicates a well-differentiated tumor? - **a) G1** - b\) G2 - c\) G3 - d\) G4 38. What does \"Tis\" indicate in the TNM staging system? - a\) Tumor size cannot be assessed - b\) No evidence of primary tumor - **c) Carcinoma in situ** - d\) Distant metastasis present 39. Which stage of cancer is characterized by metastatic spread? - a\) Stage 0 - b\) Stage I - c\) Stage III - **d) Stage IV** 40. What does \"GX\" indicate in tumor grading? - a\) Well differentiated - b\) Moderately differentiated - c\) Poorly differentiated - **d) Grade cannot be assessed** 41. What does \"N0\" indicate in the TNM staging system? - **a) No regional lymph node involvement** - b\) Regional lymph nodes cannot be assessed - c\) Regional lymph node involvement - d\) Distant metastasis present 42. Which grade indicates a poorly differentiated tumor? - a\) G1 - b\) G2 - **c) G3** - d\) G4 43. What does \"T4\" indicate in the TNM staging system? - a\) No evidence of primary tumor - b\) Small tumor size - **c) Large tumor size and/or extensive local invasion** - d\) Tumor size cannot be assessed