Viral Infection PDF
Document Details
Georgetown University
Damon Cottrell
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Summary
This document is a presentation on viral infections, discussing various aspects including viral structure, attachment, and the difference between DNA and RNA viruses. It includes a case study of a patient diagnosed with infectious mononucleosis.
Full Transcript
Viral Infection Damon Cottrell, Ph.D., DNP, APRN, FNP-C, CCNS, ACNS-BC Steven (Two Days Later) Chief complaint: “I’m not better, I’m getting worse!” HPI: has been compliant with the antibiotics, cannot swallow food without severe pain, is also complaining of nausea and left...
Viral Infection Damon Cottrell, Ph.D., DNP, APRN, FNP-C, CCNS, ACNS-BC Steven (Two Days Later) Chief complaint: “I’m not better, I’m getting worse!” HPI: has been compliant with the antibiotics, cannot swallow food without severe pain, is also complaining of nausea and left mid back and upper abdomen pain Diagnostics Rapid strep antigen repeated, negative Heterophile antibody test, positive Viral Structure Viral Attachment Involves specific interactions between surface proteins on the virus and receptors on the cell to be infected DNA vs. RNA Viruses DNA RNA Provirus Directly produce messenger RNA Enters host cell nucleus and becomes Translated in viral proteins and integrated into chromosomal DNA genomic RNA, eventually packaged Enters nucleus and is transcribed into into new viruses messenger RNA before protein Retroviruses carry the enzyme translation reverse transcriptase that creates Viral DNA that has integrated with a double-stranded DNA version of host DNA is transmitted to daughter the virus cells during mitosis—can pass to progeny Steven Steven is now appropriately diagnosed with infectious mononucleosis. He is being treated with supportive measures. He is on his way to recovery.