Thyroid Hormone PDF
Document Details
Tags
Summary
This document provides an overview of thyroid hormones, including functional anatomy, histological structure, hormones, and other related information. It is suitable for undergraduate studies in biology or related fields.
Full Transcript
FUNCTIONAL ANATOMY. Thyroid Gland Right Lobe Trachia Largest endocrine gland 15-25 gm ================================ High blood supply - =================== HISTOLOGICAL STRUCTURE ====================== Cuboidal & contains colloid. +-----------------------------------+----------------------...
FUNCTIONAL ANATOMY. Thyroid Gland Right Lobe Trachia Largest endocrine gland 15-25 gm ================================ High blood supply - =================== HISTOLOGICAL STRUCTURE ====================== Cuboidal & contains colloid. +-----------------------------------+-----------------------------------+ | Colloid Principal cells | Parafollicular cells (C cells). | +===================================+===================================+ | Parafollicular cells | | +-----------------------------------+-----------------------------------+ Homogenous material in each THYROID HORMONES ================ T3 - 10% , Responsible for most of tissue actions. lare Calcitonin - hormone secreted by Parafollicular cells, concerned with Calcium -----------------------------------------------------------------------------    ORGANIFICATION OF THYROGLOBULINS. Iodination of tyrosine residue in thyroglobulin +-----------------------------------+-----------------------------------+ | molecule. | | +===================================+===================================+ | Tyrosine is 1 ^st^ iodinated | Iodolaelone | | | | | | Calcium other iodinated | +-----------------------------------+-----------------------------------+ | at position 3 to form | substances | | Mono-iodotyrosine | | +-----------------------------------+-----------------------------------+ | | | +-----------------------------------+-----------------------------------+ 5 to form Diiodotyrosine (DI T) -------------------------------      
