Toxicology MCQ PDF

Toxicology 1. The analytical toxicologist role A. diagnosis B. management C. prevention of poisoning. D. All 2. Applications of toxicology A. Clinical toxicology B. Therapeutic drug monitoring...

Toxicology 1. The analytical toxicologist role A. diagnosis B. management C. prevention of poisoning. D. All 2. Applications of toxicology A. Clinical toxicology B. Therapeutic drug monitoring C. environmental toxicology D. all 3. ………………………………is performed using immunoassays and/or TLC A. Clinical toxicology B. Therapeutic drug monitoring C. Toxicology screening D. A and C 4. Toxicology screening Samples A. Urine B. Plasma C. Blood D. All 5. The specimens available (Forensic toxicology) A. decomposing tissues B. fresh blood C. A and B D. NON 6. Toxicological investigations of deaths and some non-fatal incidents if there is a possibility that drugs or other poisons may have been involved A. Clinical toxicology B. Therapeutic drug monitoring C. Toxicology screening D. Forensic toxicology 7. The specimens available: range from fresh blood to decomposing tissues, while the quantity available may range from a ……………….of liver to a dried bloodstain A. Half kilogram B. Kilogram C. A and B D. NON 8. during monitoring illicit drug taking in dependent patients A. Clinical toxicology B. Therapeutic drug monitoring C. Drug abuse screening D. Forensic toxicology  Toxicology 9. Urine is the specimen of choice In employment A. TLC B. immunoassay kits C. A and B D. NON 10. The measurement of plasma concentrations of drugs given in therapy used in assessing effective of therapy, and for drugs with small margin between therapeutic dosage and over dosage A. Clinical toxicology B. Therapeutic drug monitoring C. Drug abuse screening D. Forensic toxicology 11. ………………………in the case of antipsychotic and immunosuppressant drugs. A. Chromatographic assays B. MS C. Immunoassay kits D. NON 12. monitoring of occupational or environmental exposure to toxic substances A. Clinical toxicology B. Therapeutic drug monitoring C. Occupational and environmental toxicology D. Drug abuse screening 13. Types Occupational and environmental toxicology A. Incidents Chemical B. Food -derived poisons C. A and B D. NON 14. The investigation of the accidental release of chemicals into the workplace or into the environment. A. Clinical toxicology B. Incidents Chemical C. Food -derived poisons D. Drug abuse screening 15. Here analysis of the foodstuff rather than biological samples can be more helpful in establishing the diagnosis in individual patients A. Clinical toxicology B. Incidents Chemical C. Food -derived poisons D. Drug abuse screening 16. Food -derived poisons Sources: A. toxins of microbiological B. toxic plants  Toxicology C. pesticide poisoning D. All 17. ……………………e.g. atropine from Atropa belladonna and cyanide from Cassava A. toxins of microbiological B. toxic plants C. Botulinum toxin D. All 18. ………………………….sometimes occurs after ingestion of contaminated food products A. toxins of microbiological B. toxic plants C. pesticide poisoning D. all 19. Stages of analytical work in poisoning Stages case A. Pre-Analytica B. Analytica C. Post analytical D. All 20. ……………..Interpret the results in discussion with the physician. Perform additional analyses A. Pre-Analytica B. Analytica C. Post analytical D. All 21. Obtain details e.g. any circumstantial evidence of poisoning, and the results of biochemical and hematological investigations A. Pre-Analytica B. Analytica C. Post analytical D. All 22. Choice of analytical method depends on several factors including: A. the apparatus available B. the circumstances under which an analysis is requested C. the expected concentration of any analyte D. all 23. (COSHH )This include…………………………….. A. Classification, labelling and packaging of chemicals B. Health problems associated with the use of chemicals C. risk assessment D. all 24. Classification, labelling and packaging of chemicals A. a carcinogen B. a mutagen  Toxicology C. a teratogen D. all 25. Classification, labelling and packaging of chemicals A. Toxic B. Harmful C. an irritant D. All 26. …………….a substance that induces non-hereditary congenital malformations A. a carcinogen B. a mutagen C. a teratogen D. an irritant 27. ………………..a substance that induces hereditary genetic defects A. a mutagen B. a teratogen C. an irritant D. Harmful 28. …………………………….a substance directly involved in the promotion of cancer or in the facilitation of its propagation A. a mutagen B. a teratogen C. corrosive D. a carcinogen 29. ……………..a substance that causes dermatitis or asthma only after alteration of the skin or respiratory system by previous exposure to that substance A. Corrosive B. An asphyxiant C. A sensitizer D. a teratogen 30. …………………………………a substance capable of reducing the level of oxygen in the body to dangerous levels) A. Corrosive B. An asphyxiant C. A sensitizer D. a teratogen 31. Health problems associated with the use of chemicals………… A. Sensitizing substances B. Carcinogenic chemicals C. Mutagenic chemicals D. Teratogenic chemicals E. All 32. ………………..is an agent that can cause malformations of an embryo or fetus  Toxicology A. Sensitizing substances B. Carcinogenic chemicals C. Mutagenic chemicals D. Teratogenic chemicals 33. ………………cause or are suspected of causing changes to the DNA of genes A. Sensitizing substances B. Carcinogenic chemicals C. Mutagenic chemicals D. Teratogenic chemicals 34. ……………………… e.g.: dichloromethane cause cancer in humans and animals A. Sensitizing substances B. Carcinogenic chemicals C. Mutagenic chemicals D. Teratogenic chemicals 35. …………………………………………may cause infection, allergy, toxicity or otherwise create a hazard to human health A. Sensitizing substances B. Carcinogenic chemicals C. Mutagenic chemicals D. Biological agents 36. ………………e.g. Formaldehyde cause allergic reactions, respiratory problems A. Sensitizing substances B. Carcinogenic chemicals C. Mutagenic chemicals D. Biological agents 37. Health problems associated with harmful substances are likely to arise from…. A. Inhalation B. Ingestion C. Injection D. All 38. …………………developing a disease or condition as a result of contact A. Infection B. Inhalation C. Ingestion D. Injection 39. …………………..by breathing in a substance or organism A. Infection B. Inhalation C. Ingestion D. Injection 40. …………………………by eating a substance or organism A. Infection  Toxicology B. Inhalation C. Ingestion D. Injection 41. ……………………by touching a substance or organism, or it passing through the skin A. Inhalation B. Ingestion C. Injection D. Contact 42. …………………….by having a substance or organism forced through the skin A. Inhalation B. Ingestion C. Injection D. Contact 43. Control measure……………. Description Using an alternative or different process A. Substitution B. Hazard elimination C. Use of personal protective equipment D. Use of warnings 44. Control measure ………………………….Description Using signs, labels, audible alarms etc A. Substitution B. Hazard elimination C. Use of personal protective equipment D. Use of warnings 45. Control measure ………………………….Description Using safe systems of work, safe equipment, training, supervision A. Use of personal protective equipment B. Use of warnings C. Use of safety procedures D. Non 46. Control measure ………………………….Description If it cannot be eliminated, replacing a hazardous chemical with a less hazardous substance A. Substitution B. Hazard elimination C. Use of personal protective equipment D. Use of warnings 47. Control measure ………………………….Description Isolating or segregating the hazard, extraction and removal of hazardous materials from the user A. Hazard elimination B. Use of personal protective equipment C. Use of warnings D. Use of local exhaust ventilation, fume cupboards or biological safety cabinets 48. Personal protective equipment  Toxicology A. Hand protection B. Eye protection C. Laboratory coats D. All 49. Body part protected PPE used A. lab coats B. disposable gloves C. goggles D. all 50. ……………….of all kinds poses a threat to human health and the environment if it is not managed properly and recovered or disposed of safely A. Substitution B. Hazard elimination C. Waste D. Non 51. the main waste streams that are commonly found in a laboratory A. Chemical waste B. Biological waste C. Radioactive waste D. Sharps waste E. General laboratory waste F. All 52. What is Cerebrospinal fluid (CSF) A. a plasma ultrafiltrate that surrounding the central nervous system (CNS) B. a type of whole blood C. blood obtained from the umbilical cord at parturition D. non 53. how should a sample of whole blood be handled for analysis A. collected without an anticoagulant and stored at room temperature B. collected into sterile tubes and refrigerated C. collected into an appropriate anticoagulant, mixed, and then frozen in order to lyse the cells D. non 54. What is Cord blood A. The liquid portion of blood B. blood obtained from the umbilical cord at parturition C. is the pale yellow fluid remaining when whole blood has clotted. D. Non 55. How is serum obtained A. The liquid portion of blood B. blood obtained from the umbilical cord at parturition C. is the pale yellow fluid remaining when whole blood has clotted.  Toxicology D. Non 56. What is Bone marrow aspirate A. the fluid that surrounds the foetus in the amniotic sac B. humour is the watery fluid occupying the space between the cornea and the iris of the eye C. aspirate is an acidic aqueous fluid containing digestive enzymes D. is a sample of the spongy tissue found within bones that produces blood cells 57. What is Breast milk A. protein and fat B. carbohydrates C. vitamins D. all 58. What is Pericardial fluid A. fluid between blood vessels and cells B. in the lymph channel C. between the heart and the sac surrounding the heart D. non 59. what is the fluid residing within bones derived from A. Lymph B. Pericardial fluid C. peritoneal fluid D. Blood 60. what is the function Synovial fluid A. secretion of the mucous glands in the mouth B. produced by the testes and the prostate gland C. fills the synovium (the membrane that surrounds a joint and creates a protective sac D. non 61. what is the bile ? A. the yellow/yellow-green fluid produced by the kidney B. semi-solid residues of the digestive process. C. Bile is the thick yellow-green fluid secreted by the liver D. Non 62. what is the sweet A. mainly oxygen and more carbon dioxide B. the aqueous fluid excreted by the pores of the skin C. consists mainly of water, salts, urea, creatinine, and other metabolic products 63. Which sample type is sometimes used to assess exposure to drugs or toxic metals A. Hair B. Nasel swabs C. Stomach contents D. Non  Toxicology 64. How are Tissue specimens typically obtained for assessment A. By nail clippings B. at post-mortem C. toxic metals D. non 65. what is the Sample requirements for whole blood in general analytical toxicology A. 25–50 mL (plain bottle, no preservative B. 20–50 mL (plain bottle, no preservative𝑐) C. 10 mL (lithium heparin or EDTA tube D. 5 mL (send whole blood if volatiles 66. How much urine is typically required for general toxicology A. 25–50 mL (plain bottle, no preservative B. 20–50 mL (plain bottle, no preservative𝑐) C. 10 mL (lithium heparin or EDTA tube D. 5 mL (send whole blood if volatiles 67. What is a disadvantage of using post-mortem blood as a specimen in analytical toxicology A. Limited volume and low concentrations of drugs B. Difficulty in interpreting quantitative results C. High concentrations of many poisons D. Non 68. What precaution should be taken when dealing with gastric aspirate as a specimen in analytical toxicology A. Analyze the sample immediately for accurate results B. Use the sample for substance misuse screening C. Ensure no cross contamination during transport D. Non 69. What information should be provided when requesting a general toxicological analysis A. Name, sex, date of birth, and details of the sample sent for analysis B. Circumstances of the incident and insurance details C. Name, sex, and address of the clinician D. Non 70. What details should be included regarding the patient's medical history when requesting a toxicological analysis A. Information on the patient's dietary habits B. Past medical history and current medications C. Name of the patient's primary school D. Non 71. What information should be provided when requesting a general toxicological analysis A. Estimated time of transportation B. Description of recent weather conditions C. Likely cause of ingestion and quantity of substances involved D. Non  Toxicology 72. When a patient has been treated in a hospital, what should be included regarding their treatment A. Details of the patient's family history B. Summary of the relevant hospital notes C. Information about the patient's daily routine D. Non 73. How should biological specimens be stored after analysis is concluded A. Keep at –20 ∘CKeep at room temperature B. Keep at 2–8 ∘C for 3–4 weeks C. Keep at –20 ∘C D. Non 74. What is the recommended temperature for storing any remaining specimen after the incident investigation is concluded A. 8–15 ∘C B. 2–8 ∘C C. –20 ∘C D. Non 75. What should be done to ensure proper storage of samples in the freezer A. Label the tubes with non-waterproof markers B. Keep tubes loosely sealed to prevent pressure build-up C. Ensure labelling is waterproof and tubes are tightly sealed D. Non 76. Why is it important not to overfill tubes when storing samples in the freezer A. To save space in the freezer B. To prevent damage to the freezer C. To minimize freeze-drying effects D. Non 77. ‫هللا المستعان‬