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SHOCK CASE STUDIES MARGARET AVALLONE DNP RN CCRN-K, CNE RUTGERS COMPLEX HEALTH AND ILLNESS LEARNING OUTCOMES By the end of the class, the student will be able to: Apply the concepts of shock pathophysiology and management to the care of patients with hypovolemic, cardiogenic and septic shock using a...

SHOCK CASE STUDIES MARGARET AVALLONE DNP RN CCRN-K, CNE RUTGERS COMPLEX HEALTH AND ILLNESS LEARNING OUTCOMES By the end of the class, the student will be able to: Apply the concepts of shock pathophysiology and management to the care of patients with hypovolemic, cardiogenic and septic shock using a case study approach. Apply concepts of quality, safety, and patient-centered care to the care of selected patients and families in critical care environments. PATIENT #1 You are caring for Mr. C, age 70, who was admitted to your unit postoperatively 15 min ago following a L open thoracotomy for removal of a malignant tumor. Handoff report that you receive from the PACU: Vital signs BP 100/88, HR 100, respirations 18, SaO2 94% Chest tube drainage tube totals 250 ml serosanguinous drainage at 2pm since surgery. IV D5.45 at 125 ml/hr via #20 IV in the hand. U/O 30 ml/hr PMH- emphysema, HTN, (on metoprolol at home), cirrhosis THINK, PAIR, SHARE What information in the patient’s PMH is important to note in this post-surgical patient? Based on this handoff report, what are some key assessments that you will make when the patient arrives on the unit? ARRIVAL ON THE SURGICAL UNIT The UAP checks vital signs while you are assessing the patient. The UAP reports VS BP 95/88, HR 102, RR 24. Mr C. is pale, skin cool. U/O via catheter 5ml in 15 min. You find that the chest tube has drained an additional 250 ml in the last 15 min. THINK, PAIR, SHARE What immediate assessments and interventions should you take? How are you going to prioritize your actions? Assessments Interventions How might the patient’s prior medications affect the compensatory response? How would report this change in the patient condition to the care provider? SBAR HYPOVOLEMIC SHOCK- MANIFESTATIONS Anxiety, irritability, decreased LOC Poor capillary refill Pale, gray skin Tachycardia Hypotension Flat neck veins U/O decreased or absent Firstaidfor free.com CONTINUED… Unfortunately, the resident has not returned your calls. The BP increased somewhat with modified Trendelenburg, but you recognize the patient needs to be seen immediately. You recheck the VS and find: BP 74/52 -118-30, shallow, 90% The IV insertion site looks like it might be infiltrated, and you just learned how to insert IVs…… What should you do??? SOCRATIVE QUICK QUESTION In this situation, what should the new nurse do next to advocate for this patient? A. Try inserting an IV ASAP B. Use your pager phone to call the charge nurse for help starting an IV. C. Call a rapid response. D. Call the surgeon who performed the procedure. IHI Early Warning System and Rapid Response IHI EARLY WARNING SCORING SYSTEM TO INITIATE RAPID RESPONSE TEAM: CRITERIA Staff member is worried about the patient Acute change in heart rate 130 bpm Acute change in systolic BP 65 (How do you calculate mean arterial pressure??) U/O > 30ml/hr Evidence of adequate cerebral circulation Cardiac index > 2.5L/min/m2 PUTTING IT ALL TOGETHER…. Mr H, 65 yr old male admitted following an acute anterolateral MI. PMx: inferior MI Cath lab- stents placed in LAD, L circumflex PA catheter placed. Initial readings: PA pressures elevated; PCWP 28 (nl 4-12 ) Cardiac output 3.2 L/min, cardiac index (CI) 1.6 (nl > 2.5 L/min/m2) BP 80/44 mmHg MAP 56 HR 120 SaO2 88% on 100% mask. Crackles all lobes Patient cold, clammy, anxious, agitated, U/O 20ml/hr THINK, PAIR, SHARE What information suggests that the patient may be in cardiogenic shock? What therapies would you anticipate being prescribed? How could you evaluate the effectiveness of any interventions? What information does the PA catheter provide regarding how the patient’s heart is pumping? CARDIOGENIC SHOCK SIGNS/SYMPTOMS Systolic BP 100 bpm) PULMONARY ARTERY (PA) CATHETER Measures pulmonary artery pressures Pulmonary artery diastolic pressures (PAD) and wedge pressure reflects left ventricular preload. Measures cardiac output. Permits calculation of systemic vascular resistance (SVR) afterload,, Assess effectiveness of therapies, like vasoactive medications or diuretics PA WAVEFORMS- LOOK FOR THE NOTCH! Tqh.co m PULMONARY ARTERY CATHETER (SWAN-GANZ CATHETER) Transducer converts intravascular pressures to electrical waveforms. Edwards.com PULMONARY ARTERY PRESSURE MEASUREMENTS RA (CVP) 2-6 mmHg- right sided pressures PA pressures: mmHg Systolic- 15-30 Diastolic- 5-10 Mean- 10-20 Pulmonary artery diastolic (PAD) and Pulmonary capillary wedge pressure (PCWP) - 4-12mmHg. Reflect LV preload) PULMONARY ARTERY CATHETERS Cardiac Output measurements obtained either by: Intermittent measurements Continuous measurements (CCO) Non-invasive C.O. and Stroke volume technologies emerging. Reliability being evaluated. Cardiac output = HR x stroke volume CARDIOGENIC SHOCK HEMODYNAMICS Decreased Cardiac Output (CO), cardiac index (CI). Cardiac index = CO/BSA. CI- 2.5-4 L/min/m2 Increased PA pressures= increased PRELOAD! Patient is fluid overloaded. Increased SVR- patient is vasoconstricted. Increased AFTERLOAD! MANAGING CARDIOGENIC SHOCK Goals: adequate perfusion of organs- evidenced by: Mean arterial pressure (MAP) > 65 mmHg (How do you calculate mean arterial pressure??) Urine output greater than 0.5 ml/kg/hr Adequate cerebral circulation- (how would you evaluate?) Cardiac index > 2.5L/min/m2 CARDIAC OUTPUT VS CARDIAC INDEX Cardiac Output varies with age, size, and metabolic demands To compare “normal” CO between people of different sizes, we use “cardiac index”. (CI) CO/Body surface area (BSA)= cardiac index (CI) PHARMACOLOGIC THERAPY Vasoactive medications-aim is to increase cardiac output without increasing afterload Common IV vasoactive medications include dopamine, dobutamine, milrinone (phosphodiesterase inhibitor), norepinephrine, epinephrine. Action depends on medication and dose. Treat arrhythmias appropriately (KCl, MgSO4, amiodarone) Diuretics if pulmonary edema present. VASOACTIVE IV MEDICATIONS PATIENT MANAGEMENT ON VASOACTIVE MEDICATIONS VS frequently; q 15 min while titrating vasoactive meds or while unstable Dosage titrated to patient response. Titrated to BP or cardiac index goal Administer via central line if possible Extravasation may cause tissue damage Use arterial line for monitoring BP. (youtube.com) INVASIVE ARTERIAL BP MONITORING Indwelling catheter in artery. Radial, brachial, femoral arteries most frequently utilized Pressure tubing to transducer Converts pressure to electronic waveforms Youtube.com ARTERIAL LINE MONITORING Advantages Continuous monitoring Invasive- more accurate in shock states Access for blood draws including arterial ABGs Disadvantages Risk for bacteremia Risk for loss of arterial pulse (Learnpicu.com ) ARTERIAL MONITORING- PREVENT COMPLICATIONS Strict asepsis Strict line protocols Allen test prior to radial A-line insertion (or ultrasonography) Close monitoring of circulation distal to line- pulses, pallor, temp, pain AT LEAST HOURLY CIRCULATION CHECK!! (McHale 2011) McHale (2011) INTRA-AORTIC BALLOON PUMP Inflates at the beginning of diastole to “augment” coronary perfusion. (Increase myocardial blood supply). Deflates just prior to systole to reduce afterload. (Decrease myocardial oxygen demand) Vascular complications!- check pulses!! Check groin Keep leg straight Cacvi.org PUTTING IT TOGETHER (CONT.) IABP inserted Patient intubated after BiPAP failed Transferred to CCU Dobutamine drip started and titrated to achieve CI >2.5 L/min/m2 Heparin drip at 12 units/kg/hr Furosemide (Lasix) 60mg IV administered Labs drawn-Comprehensive metabolic panel (CMP), cardiac enzymes, PTT, CBC, ABGs, serum lactate. FOLLOW-UP IN THE CCU Describe the nursing care required when caring for a patient receiving dobutamine? Medication-related Interventions related to central line You are ordered to start dobutamine at 4 mcg/kg/min. The drip is mixed 500 mg in 250 ml D5W. The pt weighs 75 kg. How many ml do you set on the pump? _______ List nursing priority assessments and interventions when the patient has an IABP? SAO2 INTERPRETATION On the monitor, this is the plesmograph SpO2 waveform that is seen. What is the first action you, as the nurse should take? SOCRATIVE QUICK QUESTION 1. Assess level of consciousness, skin temperature, and color 2. Disconnect pulse oximeter device from the client and restart it 3. Preoxygenate with 100% oxygen and perform endotracheal suction 4. Reset the high and low alarm parameters on the pulse oximeter device PUTTING IT ALL TOGETHER Twelve hours later: ABGs: 7.41- 37-82- 22- 94% on mechanical ventilator (PRVC TV 700 rate 10 FIO2.4) PA readings 36/16 CO 5.2 CI 2.6 with dobutamine@ 5 mcg/kg/min U/O 50-70 ml/hr Alert, less anxious. Skin warm, dry. All pulses present with doppler. CARDIOGENIC SHOCK, CONT. IABP weaned and d/c within 48 hrs. Dobutamine weaned to off. Over the next week, Mr. H participated in in-patient cardiac rehabilitation. He was discharged to home within 10 days. Post discharge, he participated in an outpatient cardiac rehab. CASE #3 Mrs. J., a normally healthy and ambulatory 75 year old female patient has recently become lethargic, less active, and anorexic over the past week. She complains only of nonspecific lower abdominal pain unrelated to food or bowel movements. She is diagnosed with a UTI by her DNP and is prescribed TMP-SMX (Bactrim) for 7 days. CASE STUDY, CONT. The pills make her nauseous, so Mrs. J does not finish them. Three days later, she is admitted to the ED. Shaking chills, fever 101.5. PMH DM type II, HTN VS: HR 110, respirations 28, BP 90/42(58) SaO2 94% ABGs 7.51-24-74-21- 93% Admitted to general medical unit D5 1/2 75 ml/hr U/A, urine C&S, BMP. Dx UTI. Admit to medical unit. MEANWHILE, ON THE MEDICAL UNIT….. The UAP takes VS on your new admission…. T 102.5 118 28 BP 84/40 (54)!!! What do you do next? THINK, PAIR AND SHARE 1. What signs and symptoms are concerning to you? 2. What information in the patient’s history makes the patient’s presentation more concerning? 3. What should the nurse do? SEPTIC SHOCK: SIGNS AND SYMPTOMS Anxiety, restlessness, confusion, disorientation Flushed, warm, dry skin. Elderly- pale, cool, mottled. Tachypnea, dyspnea Tachycardia (HR > 90 bpm) BP < 90 systolic or fall of 40 mmHg from baseline Temp > 100.4 or < 96.8, chills. Hemodynamics: Cardiac index > 3.5 L/min/m2 (hyperdynamic) SVR < 900 (low)- vasodilated PA pressures low MEANWHILE IN THE ICU….. RECEIVING HANDOFF REPORT An ICU nurse is preparing to receive Mrs J. What information is important to receive from the providing nurse in this patient in order to help plan care? (ie- What are priorities of care for patients with septic shock; What questions should the nurse ask to support a safe transition of care to the ICU?) 2. What equipment should the nurse anticipate needing? SEPSIS RESUSCITATION BUNDLE: INITIATE WITHIN THE FIRST HOUR Multidisciplinary EBP from “Surviving Sepsis Campaign”: Measure serum lactate. > 2mmol/L indicates tissue hypoperfusion. Blood cultures prior to abx administration for sx of fever, chills, hypothermia, leukocytosis, L shift. Admin. broad spectrum abx Fluid resuscitation- initial minimum 30ml/kg crystalloid Additional fluids as needed SEPSIS RESUSCITATION BUNDLE(CONT.) Vasopressors- for hypotension and/or lactate > 4 not responding to initial fluid bolus. Maintain MAP > 65 mmHg. Use invasive arterial line to monitor BP. Norepinephrine (levophed) preferred vasopressor. Strong alpha agonist, some beta agonist activity. (1-30 mcg/min) PATIENT PARAMETERS 4 HRS POST ADMISSION TO ICU Patient has received total 1.5 L.9NSS (Patient weighs 80 kg) Norepinephrine (Levophed) infusing @ 8mcg/min via subclavian central line triple lumen catheter. VS q 15 min: T 101.1 110 28 90/46 (61) on 40% ventimask U/O 20 ml/hr Blood cultures x 2 drawn and abx started within 1 hr of ICU admission ABGs 7.21-35-80-12-94% Lactate 6 mmol/L THINK, PAIR, SHARE 1. What are your thoughts about the patient’s tissue perfusion? Adequate or inadequate? What evidence supports your conclusions? 2. What therapies would you recommend in an SBAR format with the interprofessional team? Why? 3. What procedure may be imminent for which you must prepare? THINK, PAIR SHARE Mr. H., the husband, is very concerned about his wife and wants to remain with her in the ICU after 7pm. The visiting hours in the ICU are 15 min an hour, ending at 7pm. What is the evidence concerning family visiting and patient safety and patient/family satisfaction in the ICU? SYNERGY MODEL PATIENT FAMILY CHARACTERISTICS Participation in care/Participation in decision making: Assess to what extent family participates in care and decision making? NURSE CHARACTERISTICS Advocacy- working to represent the concerns of the patients and family. Caring practices- responsiveness of caregivers to patient and family individualized needs. AACN PRACTICE ALERT: RECOMMENDATIONS Facilitate unrestricted access to a chosen support person 24 hrs/day unless contraindicated (other’s safety or rights, therapeutically or medically contraindicated). Develop policies that allow support person to be at the bedside, according to the patient’s wishes. Policies should prohibit discrimination of all kinds. AACN (2016) doi:http://dx.doi.org/10.4037/ccn2016677 THREE DAYS LATER… Patient extubated following implementation of awake and breathing trials. (ABCDE Bundle) Pressors weaned off. MAP 65-90 mmHg, U/O 50 ml/hr, Serum lactate 1.6 mmol/L Continuing antibiotics to complete course. Patient received aggressive inpatient rehabilitation prior to D/C. Patient eventually d/c to home with home care, home PT/OT. Discharge instructions include prevention of UTIs, when to call PCP, complete all antibiotics. REFERENCES AACN Practice Alert (2016). Family visitation in the Adult intensive care unit. Critical Care Nursing 36(1), doi:http://dx.doi.org/10.4037/ccn2016677 Dellinger RP, Levy MM, Rhodes A, et al.(2013) Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2012. Critical Care Medicine;41(2):580-637. Hinkle J, Cheever, K. (2018). Brunner & Suddarth’s Textbook of Medical-Surgical Nursing (14th ed.) Philadelphia, PA. Wolters Kluwer. Levy M., Evans L., Rhodes A (2018). The surviving sepsis campaign bundle: 2018 update. Intensive Care Medicine 44, 925-928. McHale-Weigand DL (2011). AACN Procedure Manual for Critical Care. St. Louis, MO. Elsevier. Qureshi, S. H., et al. (2016). Meta-analysis of colloids versus crystalloids in critically ill, trauma, and surgical patients. British Journal of Surgery, 103(1), 14–26. Society of Critical Care Medicine, European Society of Critical Care Medicine (2018). Surviving Sepsis Campaign One hour bundle. www.survingsepsis.org Yarema, T. Yost, Spencer (2011) “Low-Dose Corticosteroids to Treat Septic Shock: A Critical Literature Review.” Critical Care Nurse. 31(6) 16-26.

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