Hemodynamics Study Guide PDF
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This document provides a study guide on hemodynamics, covering key concepts such as cardiac output, preload, afterload, and contractility. It also details hemodynamic parameters, monitoring techniques, and pulmonary artery catheterization. The guide is suitable for medical students or professionals learning about the cardiovascular system.
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# Hemodynamics Study Guide ## Key Concepts - **Cardiac Output (CO):** Amount of blood pumped by each ventricle in one minute. - **Formula:** CO = Stroke Volume (SV) x Heart Rate (HR) - **Normal Range:** 4 - 8 L/min - **Cardiac Index (CI):** CO divided by body surface area (BSA). - **Normal Range:*...
# Hemodynamics Study Guide ## Key Concepts - **Cardiac Output (CO):** Amount of blood pumped by each ventricle in one minute. - **Formula:** CO = Stroke Volume (SV) x Heart Rate (HR) - **Normal Range:** 4 - 8 L/min - **Cardiac Index (CI):** CO divided by body surface area (BSA). - **Normal Range:** 2.2 - 4 L/min/m<sup>2</sup> - **Preload:** Volume in the ventricle at the end of diastole. - Reflects fluid volume status - **Afterload:** Resistance the left ventricle must overcome to pump blood. - **High Afterload:** Increased workload for the heart. - **Low Afterload:** Decreased resistance. - **Contractility:** Strength of ventricular contraction. ## Hemodynamic Parameters 1. **PAWP:** Reflects left atrial pressure. - **Normal:** 6 - 12 mmHg 2. **RAP or CVP:** Reflects right atrial pressure and fluid volume. - **Normal:** 2 - 8 mmHg 3. **MAP:** Average arterial pressure during one cardiac cycle. - **Normal:** 70 - 100 mmHg - **Formula:** MAP = SBP + 2(DBP)/3 4. **CI:** CO adjusted for BSA. - **Normal:** 2.2 - 4 L/min/m<sup>2</sup> 5. **CO:** Volume of blood pumped per minute. - **Normal:** 4 - 8 L/min 6. **PAP:** - **Pulmonary Artery Pressure= PAS (Systolic):** 20 - 30 mmHg - **PAD (Diastolic):** 8 - 12 mmHg - **PAM:** ~25 mmHg - **Increased PAWP:** Indicates fluid overload. - **Decreased PAWP:** Suggests hypovolemia. - **Increased CVP:** Indicates fluid volume excess. - **Decreased CVP:** Suggests fluid deficit. ## Hemodynamic Monitoring - Measures pressure, flow, and oxygenation in the cardiovascular system. - Goal: Assess heart function, fluid balance, and effects of drugs on CO. - **Parameters Measured:** - **Pulmonary Artery Wedge Pressure (PAWP):** Reflects left atrial pressure (via Swan-Ganz catheter). - **Central Venous Pressure (CVP):** Reflects right ventricular preload (via triple-lumen catheter or PA catheter). - **Pulmonary Arterial Pressures (PA):** Monitored using Swan-Ganz catheter - **CO/CI:** Assesses cardiac output and function. ## Pulmonary Artery Catheter (Swan-Ganz) - **Purpose:** Inserted into a central vein and floated into the pulmonary artery to measure: - **Pulmonary Artery Pressures (PAS, PAD).** - **PAWP:** Indirect measure of left atrial pressure - **CVP:** Right atrial pressure. - **CO and CI** - **Key Features:** 1. **Balloon Tip:** - Inflate Max of 1.5 mL for Max 15 sec to measure PAWP. - Overinflation of balloon (Wedging) can cause rupture of PA. 2. **Lumens:** - **2 Proximal Lumen:** Measures CVP; used for fluids, meds, or blood draws. - **Distal Lumen:** Measures PAS, PAD, and PAM. - **Temp sensor near distal tip** 3. **Markings:** - Thin lines = 10 cm, thick lines = 50 cm - Helps monitor catheter placement. ## Principles of Invasive Pressure Monitoring & Phlebostatic Axis - **Purpose:** Ensures accurate pressure readings during hemodynamic monitoring. - **Key Points:** 1. **Equipment Setup:** - Must be referenced and zero-balanced to the environment. - Optimize dynamic response characteristics for precise readings. 2. **Referencing**: PT in supine position - Align transducer to the phlebostatic axis: - Intersection of midaxillary line (between anterior and posterior) and through 4th intercostal space - Represents the level of the atria when the patient is supine. 3. **Zeroing:** - Confirms that when pressure w/in system is zero, the monitor reads zero. - **How:** Open reference stopcock to air (off to patient). - Perform during initial setup and periodically thereafter. - **Goal:** Maintain proper equipment alignment and calibration for reliable measurements. ## Pulmonary Artery (PA) Monitoring - **Purpose:** Guides management of cardiopulmonary conditions by providing detailed measurements of heart function and fluid volume. - **Key Details:** 1. **PA Pressure Tracing:** - Before balloon inflation, the waveform resembles arterial tracing: - Features a systolic peak, dicrotic notch, and diastolic low point. - As the balloon inflates and “wedges,” the waveform changes shape and amplitude. 2. **Measurements:** - **PAWP:** Inflated balloon measures left atrial pressure - **PAS/PAD:** Indicate pulmonary artery pressures. - PAWP and PAD are sensitive indicators of heart function and fluid volume status - Allows precise manipulation of preload - **Specialized Features:** - Atrial electrode, Fiberoptic sensor for mixed venous O2 saturation. - Continuous: right ventricular volume, EF, and CO monitoring data w/ additional ports for IV access ## Pulmonary Artery Waveforms - **Waveform Stages During Insertion:** 1. **Right Atrium (RA):** Low pressure with smooth waves. 2. **Right Ventricle (RV):** - Recorded only during insertion; note for the cardiologist. - Sharp peaks with increased systolic pressure. 3. **Pulmonary Artery (PA):** Clear systolic/diastolic pressures with a dicrotic notch. 4. **PAWP (Wedge Pressure):** Flattened waveform during balloon inflation. ## Complications of Pulmonary Artery Catheter 1. **Infection and Sepsis:** - Use aseptic technique during insertion & maintenance - Change tubing, flush bag, stopcock and transducer every 96 hours. 2. **Air Emboli (e.g Disconnection):** - Monitor Ballon integrity - Luer-lok connections and alarms on 3. **Pulmonary Artery Rupture/Infarction:** - Avoid overinflating the balloon, Do not exceed 1.5 mL during inflation. - Over wedging can rupture the pulmonary artery due to excessive pressure. - Monitor waveforms continuously - Maintain continuous flush system 4. **Ventricular Dysrhythmias:** - Monitor ECG during catheter insertion, removal, or migration of PA catheter. ## Central Venous Pressure (CVP) Monitoring - Measurement of right ventricular preload that reflects fluid volume - Obtained from: - Central venous catheter - PA catheter - Similar to PAWP waveforms ## Measuring Cardiac Output - Continuous Cardiac Output (CCO) - PA catheter with thermal filament located in right atrium - Senses change in temperature of blood as it passes through right ventricle - Measures every 30 to 60 seconds - Reflects average CO for past 3 to 6 minutes ## What Do the Values Mean? - PA, CVP, and PAWP measure heart function and fluid balance - PA pressures = pressure in the pulmonary artery - CVP = measurement of vena cava or right atrium; reflects fluid volume status - PAWP = measures Left atrial pressure - To sum it up.... These numbers are really evaluating preload, which is a volume issue ## A-Line Monitoring - **Purpose:** Provides continuous BP monitoring - **Placement:** - Radial artery is commonly used. - Sutured in place, then immobilize arm (w/ board) to secure. Don't want movement - Perform an Allen test to assess collateral circulation before insertion. - **Used For:** - PTs on vasopressors, FQ ABG sampling, Shock, acute hemodynamic instability, acute hypotension, PT needs continuous monitoring of BP - **Note:** NEVER GIVE IV FLUIDS THROUGH ART LINE ## A-Line Waveforms - Correspond to ECG rhythm, QRS corresponding to atrial wave form - **Dicrotic Notch:** Indicates valve closure. - **Square Wave Test:** Confirms proper zeroing and flushing of the A-line system. ## Nursing Interventions with A-Line 1. **Hemorrhage Prevention:** - Ensure Tight Luer-Lok connections including tubing. - Activate monitor alarms. - Check arterial waveform (look for a good dicrotic notch). 2. **Infection Monitoring:** - Monitor for local signs of inflammation. - Change pressure tubing, flush bag, and transducer every 96 hours. 3. **Circulation Monitoring:** - Perform Allen test before insertion: - **Positive Allen Test:** Pinkness doesn't return in 6-7 seconds. - Hourly checks for circulation (look for paralysis, pain, paresthesia). Emergency if impaired 4. **Ensure Correct Waveform and A-Line BP Correlation:** - Ensure A-line BP matches ECG waveform. 5. **Leveling and Zeroing:** - Calibrate the A-line system. 6. **Removing A-Line:** - Remove sutures first. - Hold pressure for 5 minutes (radial) or 10 minutes (femoral). - Monitor closely for bleeding. ## Noninvasive Hemodynamic Monitoring - Uses external sensor pads placed around heart to measure cardiac output (CO) and cardiac index (CI) - **Advantages:** Less invasive than Swan-Ganz Catheter # Cardiogenic Shock Overview ## Definitions - **Cardiogenic Shock:** - A syndrome characterized by decreased tissue perfusion and impaired cellular metabolism due to an imbalance in oxygen/nutrient supply and demand. - **Pathophysiology:** - **Systolic Dysfunction:** Heart cannot pump blood forward (↓ stroke volume and cardiac output < 4 L/min). - **Diastolic Dysfunction:** Heart cannot fill properly (↓filling → ↓ stroke volume). - Results in severe pump failure, vasoconstriction, and increased central venous pressure (CVP) and pulmonary artery wedge pressure (PAWP). ## Causes - **Systolic Dysfunction:** - Myocardial infarction (most common) - Cardiomyopathy, blunt cardiac injury - Severe systemic or pulmonary hypertension - Myocardial depression from metabolic issues. - **Result:** Impaired contractility, thin/weak heart muscle, low ejection fraction (<50%). - **Diastolic Dysfunction:** - Cardiac tamponade (requires pericardiocentesis) - Ventricular hypertrophy, cardiomyopathy - Structural issues: valvular stenosis/regurgitation, tension pneumothorax, ventricular septal rupture. - **Result:** Impaired filling/ relaxation, Thick/stiff heart muscle, normal ejection fraction. ## Clinical Manifestations - **Early Signs:** - Tachycardia, hypotension, narrow pulse pressure - Increased myocardial oxygen Consumption - Angina, fatigue, a sense of impending doom - Signs of hemodynamic instability - **Physical Findings:** - Cool, clammy skin, pallor, delayed capillary refill - Pulmonary congestion (crackles), tachypnea - Anxiety, confusion, agitation - Decreased urine output ## Complications - **Cardiac Arrest:** - Due to organ hypoperfusion and myocardial workload. - **Causes:** - Persistent myocardial ischemia or ventricular dysrhythmias. - **Associated Diagnoses:** - Acute coronary syndromes, ventricular rupture, pulmonary embolism. ## Diagnostics - **Lab Tests:** - Troponin, BNP, CPK-MB, BMP, CBC, lactic acid - **Imaging:** - **Echocardiogram:** Assess ejection fraction. - **12-lead ECG:** Identify ischemia, infarction, or dysrhythmias - **Chest X-ray:** Detect pulmonary congestion or structural issues. ## Nursing Assessments - **Neurological:** - Monitor for decrease or changes in LOC, anxiety, restlessness. - **Respiratory:** - Assess oxygen saturation, work of breathing, crackles on auscultation. - **Cardiac:** - Chest pain, Temp, HR, Continuous ECG & 12 lead, BP, CVP, PA pressures, C/O - Monitor for dysrhythmias, murmurs (S3, S4 gallops), chest pain. - **Renal:** - Monitor urine output hourly (report <30 mL/hr for 2 hours). - Assess edema, BUN, creatinine, and electrolytes. - **Gastrointestinal:** - Monitor NGT, bowel sounds, abdominal distention, and for ischemic bowel symptoms. ## Nursing Care - **Respiratory:** - Provide oxygen therapy, BiPAP (decreases Pre/afterload), or mechanical ventilation. - Administer diuretics to reduce preload and pulmonary edema - **Cardiac:** - Continuous ECG monitoring, hemodynamic profiles - Vital signs every 15 minutes. - Prevent DVTs; manage assistive devices and IV gtts - **Gastrointestinal:** - Diet consult, small bore feeding tube, Initiate low/slow enteral feeding within first 24 hours. - Prevent ulcers with PPIs; use stool softeners if needed for bowl regiment - **Renal:** - Monitor fluid retention and manage edema. - hemodialysis or Consider CRRT for unstable patients needing blood purification. ## Nursing Focus - **Decrease Workload:** - **Nitrates (e.g., Nitroglycerin):** Dilate coronary arteries. - **Considerations:** Glass bottle, Avoid with erectile dysfunction drugs (Avanafil, sildenafil, tadalafil, varde) causes severe hypotension, monitor for hypotension, dizziness, headache, syncope - **Reduce Preload:** - **Diuretics (e.g., Furosemide- IVPB, Bumetanide-IBPB/gtt):** Decrease pulmonary congestion. - **Considerations:** Monitor potassium, risk of ototoxicity. - **Reduce Afterload:** - **Vasodilators (e.g., Nitroprusside):** Lower systemic vascular resistance. - **Considerations:** Risk of: cyanide toxicity (after 36 hours), headache, dizziness, increased ICP, brady/ tachycardia, hypotension, palpitations; Administer: very small doses (very potent), protect from light. - **Increase Contractility:** - **Inotropes (e.g., Dopamine, Epi, Dobutamine, Milrinone):** Improve cardiac output. - **Considerations:** Dobutamine- initial hypotension then increases BP, Monitor CO/CI, ONLY use deep line for administration. ## Interprofessional Care - **Overall Goal:** - Restore myocardial blood flow by restoring Balance oxygen supply and demand. - **Key Procedures:** - Angioplasty with stenting (percutaneous transluminal coronary angioplasty (PTCA) - Valve replacement - Emergency revascularization & Prevent cardiac arrest - **Drug Therapy:** - Nitrates (dilate coronary artery), diuretics (reduce preload), vasodilators (decrease afterload, achieve/maintain MAP >65), B-adrenergic blockers (decrease HR) - **Circulatory Assistive Devices:** Decrease SVR and left ventricular workload - IABP: Decreases systemic vascular resistance and myocardial workload. - VAD: Supports ventricular function. - Heart transplantation: For end-stage failure. ## Heart Catheterization: Percutaneous coronary intervention (PCI) - **Purpose** - To restore oxygen supply and demand balance in cardiogenic shock. - Diagnostic and therapeutic procedure to identify and reduce blockages in coronary arteries. - **Key Timeframes: Door-to-Balloon Time Goal-** Coronary artery should be reopened within 90 minutes after patient arrival. ## Pre-Procedure Interventions 1. **IV Access:** Insert two large-bore IVs. 2. **Consent:** Obtain consent for the procedure and blood products. 3. **Medications:** - **Thrombolytics:** To dissolve clots. - **Anticoagulants (e.g., Heparin):** Prevent further clot formation (monitor PTT). - **Antiplatelets (e.g., Aspirin, Clopidogrel):** Reduce platelet aggregation. - **Pain Management (e.g., Morphine):** Relieve chest pain and anxiety. ## Nursing Considerations overall of cardiogenic shock - Maximizing oxygen delivery to tissues. - Bedrest to decrease oxygen demands. - Oxygen support & mechanical ventilation. - Maintaining an adequate H & H. - Palliative care consult.