Sedative Hypnotics Lecture 1 PDF
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Uploaded by InspirationalLead9469
Menoufia University
Dr. Amany Tawfik Elfakhrany
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Summary
This lecture provides an overview of sedative and hypnotic drugs. It covers classifications, ideal characteristics, and mechanisms of action. The document also explores the advantages and disadvantages of benzodiazepines and barbiturates.
Full Transcript
Sedative – Hypnotic Drugs Dr. Amany Tawfik Elfakhrany Assistant Professor of Clinical Pharmacology Faculty of Medicine Menoufia University SEDATIVE HYPNOTIC A drug calm the patient at A drug that produces a a dose that not produces state iden...
Sedative – Hypnotic Drugs Dr. Amany Tawfik Elfakhrany Assistant Professor of Clinical Pharmacology Faculty of Medicine Menoufia University SEDATIVE HYPNOTIC A drug calm the patient at A drug that produces a a dose that not produces state identical with sleep sleep IDEAL ANXIOLYTIC IDEAL HYPNOTIC DRUG DRUG Calm the patient without Quick onset daytime sedation Taken orally No physical or physiological Adequate duration dependence No tolerance, habituation, Very low toxicity dependence No drug interaction No drug hangover Very low toxicity No drug interaction CLASSIFICATION: Drugs act Barbiturates , Benzodiazepine on GABA Buspirone,Paraldehyde,Chloral Other hydrate,Meprobamate&Glutethimide sedatives Others:Clonidine, Antihistaminics,Antidepressant &B.blockers (pass BBB) (Most widely used Anxiolytic drug) (according to T1/2) Long acting Intermediate Short acting T1/2 >24hr acting T1/2
