Liver Function: Section 5 PDF
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Uploaded by MindBlowingElder794
Dr Ghada Mohammed
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Summary
This document is a presentation on liver function. It details the various functions of the liver, including metabolic, detoxification, hematological, and synthetic functions. It also covers storage functions and provides examples of liver dysfunction and associated tests. The presentation is well-organized and uses various headings to logically explain the topics.
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Section 5 Dr Ghada Mohammed 1 Function of Liver 1- Metabolic Functions 2- Production of bile salts :Helps in digestion 3- Detoxification and excretion 4- Hematological function 5- Synthetic functions 6- Storage Functions Dr Ghada Mohammed 2 ...
Section 5 Dr Ghada Mohammed 1 Function of Liver 1- Metabolic Functions 2- Production of bile salts :Helps in digestion 3- Detoxification and excretion 4- Hematological function 5- Synthetic functions 6- Storage Functions Dr Ghada Mohammed 2 1-Metabolic Functions: Glycogen synthesis Vitamin Metabolism Lipid Metabolism Glycolysis Dr Ghada Mohammed 3 3- Detoxification and excretion Ammonia to urea (urea cycle), bilirubin, cholesterol, drug metabolites Dr Ghada Mohammed 4 4-Hematological function: Formation of Blood Destruction of erythrocyte Dr Ghada Mohammed 5 5-Synthetic functions: Plasma proteins (albumin, globulins) cholesterol triglycerides lipoprotein Dr Ghada Mohammed 6 6- Storage Functions: Glycogen, Vitamin A, D and B12 Dr Ghada Mohammed 7 ØSome example of liver dysfunction Hepatocellular disease Cholestasis Cirrhosis Hepatitis Jaundice Liver cancer Steatosis (fatty liver) Dr Ghada Mohammed 8 Ø Liver function tests Used to detect the presence of liver disease distinguish among different types of liver disorders Dr Ghada Mohammed 9 Ø Classification of LFTs 1- Group I: Markers of liver dysfunction 2-Group II: Markers of hepatocellular injury 3-Group III: Markers of cholestasis Dr Ghada Mohammed 10 1- Group I: Markers of liver dysfunction Serum bilirubin: total and conjugated Urine: bile salts and urobilinogen Total protein serum albumin albumin/globulin ratio Prothrombin Time PT Bledding BT Clotting Time (CT) Dr Ghada Mohammed 11 2-Group II: Markers of hepatocellular injury Alanine aminotransferase (ALT) SGPT Aspartate aminotransferase (AST) SGOT 3-Group III: Markers of cholestasis Alkaline phosphatase (ALP) Gama-glutamyltransferase (GGT) Dr Ghada Mohammed 12 Dr Ghada Mohammed 13
