Pituitary and Hypothalamic Part 2 PDF

Summary

This document covers questions and answers related to desmopressin, a vasopressin analog, and its clinical applications. It discusses the mechanisms of desmopressin, including its receptor selectivity, and its clinical uses. It also identifies potential side effects and contraindications.

Full Transcript

\#\#\# \*\*Slide 10: Vasopressin Analog - Desmopressin (DDAVP)\*\* 1\. \*\*Desmopressin (DDAVP) primarily acts on which receptor to reduce urine output in diabetes insipidus?\*\* \- A. V1 receptors \- B. V2 receptors \- C. Alpha receptors \- D. Beta receptors \*\*Answer:\*\* B. V2 receptors【1...

\#\#\# \*\*Slide 10: Vasopressin Analog - Desmopressin (DDAVP)\*\* 1\. \*\*Desmopressin (DDAVP) primarily acts on which receptor to reduce urine output in diabetes insipidus?\*\* \- A. V1 receptors \- B. V2 receptors \- C. Alpha receptors \- D. Beta receptors \*\*Answer:\*\* B. V2 receptors【128†source】 2\. \*\*What is the primary clinical use of desmopressin?\*\* \- A. Induce labor \- B. Treat central diabetes insipidus and nocturnal enuresis \- C. Increase blood pressure \- D. Reduce postpartum hemorrhage \*\*Answer:\*\* B. Treat central diabetes insipidus and nocturnal enuresis【128†source】 3\. \*\*Which of the following is a side effect associated with desmopressin therapy?\*\* \- A. Hyponatremia \- B. Hyperkalemia \- C. Hypercalcemia \- D. Hypertension \*\*Answer:\*\* A. Hyponatremia【128†source】 \-\-- \#\#\# \*\*Slide 11: Vasopressin and Desmopressin - Clinical Applications\*\* 1\. \*\*In addition to diabetes insipidus, desmopressin is used to treat which bleeding disorder?\*\* \- A. Hemophilia A \- B. Von Willebrand disease \- C. Disseminated intravascular coagulation \- D. Idiopathic thrombocytopenic purpura \*\*Answer:\*\* B. Von Willebrand disease【128†source】 2\. \*\*Which of the following is a contraindication to desmopressin use?\*\* \- A. Hyponatremia \- B. Hyperkalemia \- C. Hypertension \- D. Diabetes mellitus \*\*Answer:\*\* A. Hyponatremia【128†source】 3\. \*\*What is a key difference between vasopressin and desmopressin regarding receptor selectivity?\*\* \- A. Desmopressin has greater selectivity for V2 receptors, reducing vasoconstriction effects \- B. Vasopressin is more selective for V2 receptors \- C. Desmopressin increases both V1 and V2 receptor activity \- D. Vasopressin only acts on alpha receptors \*\*Answer:\*\* A. Desmopressin has greater selectivity for V2 receptors, reducing vasoconstriction effects【128†source】

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