Pharmaceutical Chemistry Orbital Hybridization MCQ PDF

Summary

This document is a collection of multiple-choice questions (MCQs) on the topic of orbital hybridization in pharmaceutical chemistry. The questions cover various molecular structures and their corresponding hybridization types. It's designed as a practice test or tutorial.

Full Transcript

PL1001 Pharmaceutical Chemistry ORBITAL HYBRIDISATION MCQ Dr Alberto Di Salvo MCQ tutorial 1. Which molecule is shown with its correct molecular shape? (a) H2O - trigonal bipyramidal (b) CH4 - tetrahedral ✔ (c) BF3 - bent (d) SF6 - pyramidal...

PL1001 Pharmaceutical Chemistry ORBITAL HYBRIDISATION MCQ Dr Alberto Di Salvo MCQ tutorial 1. Which molecule is shown with its correct molecular shape? (a) H2O - trigonal bipyramidal (b) CH4 - tetrahedral ✔ (c) BF3 - bent (d) SF6 - pyramidal (e) CO2 - tetrahedral 2. Which of the following species is linear? (a) NH3 (b) H2O ✔ (c) CO2 (d) PF3 (e) PCl3 MCQ tutorial 3. The F-S-F bond angles in SF6 are ______. (a) 109o28' (b) 120o only (c) 90o and 120o (d) 45o and 90o (e) 90o and 180o ✔ MCQ tutorial 4. A (pi) bond is the result of the (a) overlap of two s orbitals. (b) overlap of an s and a p orbital. (c) overlap of two p orbitals along their axes. (d) sideways overlap of two parallel p orbitals. ✔ (e) sideways overlap of two s orbitals. 5. A triple bond contains ___ sigma bond(s) and ___ pi bond(s). (a) 0, 3 (b) 3, 0 (c) 2, 1 (d) 1, 2 ✔ (e) 3, 2 MCQ tutorial 6. Identify the hybridisation of carbons A and B in the structure of aspirin B COOH A A sp2 B sp3 O CH3 O 7. Identify the hybridisation of atoms A, B and C in the structure of the β-lacam antibiotic drawn below O A sp2 S B sp3 A CH3 C sp3 R C N N CH3 CH3 O X B O O O MCQ tutorial 8. Identify the hybridisation of carbons A and B in the structure below B A A sp3 HO COOH B sp2 H NH2 HO L-dopa 9. Identify the hybridisation of atoms A, B, C and D in the structure below C N D N O 8 CH3 O A sp3 A B sp3 N CF3 C sp3 D sp3 S Fluphenazine decanoate B MCQ tutorial 10. Explain the hybridisation involved in the following molecules and draw their molecular structure: PF3, SF6, H2O, NH3, NH4+. PF3 = sp3, pyramidal; SF6 = sp3d2, octahedral; H2O = sp3, bent; NH3 = sp3, pyramidal; NH4+ = sp3, tetrahedral. 11. Draw the structure of ethanoic acid and explain the hybridisation involved in each of the carbon atoms. sp2 H 3C OH sp3 O

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