NitroGlycerin PDF

GENERIC NAME nitroglycerin TRADE, BRAND, OR PROPRIETARY NAMES Nitro-Bid® Nitrolingual® Nitrostat® Others CLASSES Vasodilator Antianginal Nitrate STANDARD SUPPLIES Tablet Spray bottle MECHANISMS OF ACTION Relaxes vascular smooth muscle Dilates coronary arteries resulting in increased blood flow to th...

GENERIC NAME nitroglycerin TRADE, BRAND, OR PROPRIETARY NAMES Nitro-Bid® Nitrolingual® Nitrostat® Others CLASSES Vasodilator Antianginal Nitrate STANDARD SUPPLIES Tablet Spray bottle MECHANISMS OF ACTION Relaxes vascular smooth muscle Dilates coronary arteries resulting in increased blood flow to the myocardium Decreases workload on the heart Decreases myocardial oxygen demand Decreases preload Decreases afterload INDICATIONS Chest pain and signs/symptoms suggestive of the acute coronary syndrome Congestive heart failure with pulmonary edema CONTRAINDICATIONS Hemodynamically significant hypotension Hypovolemia The patient has taken an erectile dysfunction medication in the previous 48 hours including o sildenafil (Viagra®) o tadalafil (Cialis®) o vardenafil (Levitra®) o Other phosphodiesterase-5 inhibitor medications Not recommended for use with pediatric patients NITROGLYCERIN 1 ADVERSE REACTIONS/SIDE EFFECTS Hypotension Bradycardia Tachycardia Headache Dizziness Weakness Syncope Nausea Vomiting ROUTE OF ADMINISTRATION Sublingual ONSET OF ACTION 1 to 3 minutes ADULT DOSAGES Tablet: 0.4 mg Single spray: 0.4 mg May repeat the dosage in 3 to 5 minutes twice after the initial dosage SPECIAL CONSIDERATION The peak effect of the drug is 5 to 10 minutes The duration of the drug is 20 to 30 minutes NITROGLYCERIN 2