University Of San Agustin Pharmacology Learning Module PDF

University of San Agustin General Luna St., Iloilo City 5000, Philippines www.usa.edu.ph COLLEGE OF HEALTH AND ALLIED MEDICAL PROFESSIONS-NURSING...

University of San Agustin General Luna St., Iloilo City 5000, Philippines www.usa.edu.ph COLLEGE OF HEALTH AND ALLIED MEDICAL PROFESSIONS-NURSING PROGRAM Learning Module in NCM 106 PHARMACOLOGY Prepared by: John Ian L. Lamasan, M.A.N., R.N. A Legacy of Excellent Education in Virtus et Scientia Email: [email protected] | Tel. No.: (033) 337-4841 to 44 | Fax No.: (033) 337-4403 jilamasan  University of San Agustin General Luna St., Iloilo City 5000, Philippines www.usa.edu.ph COLLEGE OF HEALTH AND ALLIED MEDICAL PROFESSIONS-NURSING PROGRAM NCM 106: PHARMACOLOGY MODULE 3 DRUGS AFFECTING IN THE BODY SYSTEM Module Overview This module is designed for nursing students to have a comprehensive introduction to the concepts, principles of Pharmacology and to Integrate knowledge of physical, social, natural and health sciences and humanities in nursing pharmacology Module Outcomes At the end of the module the learner should be able to: 1. Provide appropriate health education related to drug therapy. 2. Evaluate compliance and response of client to the medications prescribed. 3. Use available clinical evidence that can ensure safe medication administration. 4. Document client’s condition/response/ outcomes related to drug therapy. 5. Manage resources (human, physical, financial, time) efficiently and effectively in safe drug administration. Use appropriate communication/ interpersonal techniques/strategies to ensure a working relationship with the client and/or support system in medication administration. Ensure intra-agency, inter-agency, multidisciplinary and sectoral collaboration in medication administration. Assume personal responsibility to keep abreast with current trends in nursing pharmacology Exemplify love for country in the service of the Filipinos. Discuss various technological advances in ensuring safe medication administration Manifest professionalism and excellence in planning for safe medication practice. Module Content: a. Reproductive System b. Pregnancy and Pre-term labor drugs c. Labor and Delivery and Neonatal drugs d. Postpartum and Newborn drugs e. Women’s Reproductive Health and Menopause f. Men’s Reproductive Health and Reproductive Disorders g. Infertility and Sexually Transmitted Infections A Legacy of Excellent Education in Virtus et Scientia Email: [email protected] | Tel. No.: (033) 337-4841 to 44 | Fax No.: (033) 337-4403 jilamasan  University of San Agustin General Luna St., Iloilo City 5000, Philippines www.usa.edu.ph COLLEGE OF HEALTH AND ALLIED MEDICAL PROFESSIONS-NURSING PROGRAM MEN’S REPRODUCTIVE HEALTH AND REPRODUCTIVE DISORDERS Reproductive health implies that men and women at developmentally appropriate life stages are fertile (i.e., able to produce gametes [sperm or eggs]). It entails the ability to engage in sexual intercourse with ejaculation by the male. SUBSTANCES RELATED TO MALE REPRODUCTIVE DISORDERS ANDROGENS Androgens, or male sex hormones, control the development and maintenance of sexual processes, accessory sexual organs, cellular metabolism, and bone and muscle growth. Testosterone is the principal male sex hormone and is an anabolic steroid. It is the prototype of the androgen hormones, synthesized primarily in the testes and, to a lesser extent, in the adrenal cortex. ANDROGENS Generic Name Route and Uses Side Effects and Pregnancy (Brand Name) Dosage Special Consideration Category NATURAL ANDROGENS testosterone IM: To achieve normal Side Effects: X enanthate 50-400 mg androgen levels; to Abdominal pain, nausea, (Delatestryl) q2-4wk slow progress of diarrhea, constipation, hives, estrogen-dependent irritation at injection site, breast cancers increased salivation, mouth soreness, increased or Mode of Action: decreased libido, insomnia, Develops and aggressive behavior, maintains male sex weakness, dizziness, pruritus organs and secondary sex FDA boxed warning for characteristics children exposed to gel: inappropriate enlargement of the genitalia (penis or clitoris), premature development of pubic hair, advanced bone aging, increased libido, and aggressive behavior Adverse Reactions: Acne, masculinization, irregular menses, urinary urgency, gynecomastia, priapism, red skin, jaundice, sodium and water retention, allergic reaction, depression, habituation Life-threatening: Hepatic necrosis, hepatitis, hepatic tumors, respiratory Distress Contraindications: Pregnancy, nephrosis, hypercalcemia, pituitary insufficiency, hepatic dysfunction, benign prostatic A Legacy of Excellent Education in Virtus et Scientia Email: [email protected] | Tel. No.: (033) 337-4841 to 44 | Fax No.: (033) 337-4403 jilamasan  University of San Agustin General Luna St., Iloilo City 5000, Philippines www.usa.edu.ph COLLEGE OF HEALTH AND ALLIED MEDICAL PROFESSIONS-NURSING PROGRAM hypertrophy, prostatic cancer, history of myocardial infarction, prepubertal status, non–estrogen-dependent breast cancer SYNTHETIC ANDROGENS Danazol PO: Endometriosis, 100-800 fibrocystic breast Initial doses are gradually mg/d in 2 disease, hereditary reduced on an individual divided angioedema. basis. doses initially methyltestosterone PO: Androgen X (Android, 10-50 mg/d deficiency, Methitest, in divided carcinoma of the Testred) doses breast. initially, reduced for maintenance ANABOLIC STEROIDS oxandrolone Adult PO: Cachexia, delayed X (Oxandrin) 2.5-20 mg/d, growth/puberty, osteoporotic divided pain, short stature, Turner’s Child PO: syndrome, alcoholic hepatitis.