Medical Gross Anatomy – Lecture 15 – Heart Development PDF

Notice and Agreement Medical Gross Anatomy – Lecture 15 – Heart Development This session is being recorded Class recordings are distributed for the exclusive use of students in the LMU DeBusk College of Osteopathic Medicine....

Notice and Agreement Medical Gross Anatomy – Lecture 15 – Heart Development This session is being recorded Class recordings are distributed for the exclusive use of students in the LMU DeBusk College of Osteopathic Medicine. Student access to and use of class recordings are conditioned on agreement with the terms and conditions set below. Any student who does not agree to them is prohibited from accessing or making any use of such recordings. Any student accessing class recordings (1) acknowledges the faculty members’ intellectual property rights in recorded lectures and class materials and that distribution of the recordings violates the DCOM Copyright Policy; (2) recognizes the privacy rights of fellow students who speak in class; (3) accepts that distributing, posting, or uploading class recordings to students or any other third party not authorized to receive them or to those outside DCOM is an Honor Code violation; and (4) agrees that recordings are to be accessed and used only as directed by the faculty member(s) teaching the course. ©AK2023  Medical Gross Anatomy Lecture 15: Heart Development 24 August 2023 Adam Kolatorowicz PhD Langman’s Medical Embryology 14th ed. Ch 13 pp 181-204, 216-219 (Ignore all sections on molecular regulation.) Anatomy of the Human Body (Gray, 1918) Fig. 463. Heart of human ©AK2023 embryo of about fourteen days. (From model by His.)  Learning Objectives 1. Describe the formation and positioning of the heart tube. 2. Identify embryonic tissues that give rise to cardiovascular structures. 3. Explain the formation of the cardiac chambers, septa, and valves. 4. Diagnose congenital heart anomalies based on physical exam findings. 5. Compare and contrast circulation before and after birth. ©AK2023 3 Langman's Medical Emb ryology 14th ed. Fig. 13.38 Introduction Cardiovascular system is first major system to function in the embryo Primordial heart and vascular system appear in middle of wk 3 Rapidly growing embryo can no longer satisfy nutritional and oxygen requirements from diffusion LO2 Derived from mesoderm with contributions from neural crest ©AK2023 4 LO1 Formation and Position of Heart Tube Cardiogenic area is originally anterior to future mouth and forebrain Forebrain grows over heart to lie in thorax position Lateral folding of embryo brings paired cardiac tubes together as single tube ©AK2023 The Developing Human 10th ed. Fig. 13-9 5 LO1 Formation and Position of Heart Tube ©AK2023 The Developing Human 10th ed. Fig. 13-8 6  LO1 Langman's Medical Emb ryology 14th ed. Fig. 13.8 day 22 day 23 day 24 Formation of Cardiac Loop ©AK2023 7  Anomaly of Cardiac Looping ©AK2023 The Developing Human 10th ed. Fig. 13-23 8 LO2 Development of Sinus Venosus Quadrangular space that precedes atria Receives all blood from the embryo (L and R sinus horns) Right sinus horn ©AK2023 Langman's Medical Emb ryology 14th ed. Fig. 13.11 9 LO2 Development of Sinus Venosus L horn gets smaller after contributing veins degenerate Remains as coronary sinus R horn enlarges greatly from L to R shunting of blood Develops into valves of IVC and valves of coronary sinus ©AK2023 Langman's Medical Emb ryology 14th ed. Fig. 13.12 10