Medical Microbiology Midterm Exam (PDF)

## Select One Best Answer for each of the following questions. (15 marks, 0.75 each) 1. Wool-sorter's disease is another name of - A. Cutaneous anthrax - B. Pneumonic anthrax - C. Intestinal anthrax - D. None of these 2. What is the correct profile of *Streptococcus pneumoniae*?...

## Select One Best Answer for each of the following questions. (15 marks, 0.75 each) 1. Wool-sorter's disease is another name of - A. Cutaneous anthrax - B. Pneumonic anthrax - C. Intestinal anthrax - D. None of these 2. What is the correct profile of *Streptococcus pneumoniae*? - A. Gram positive cocci / chains / optochin resistant /capsulated/ bile soluble - B. Gram negative /diplococci/ optochin sensitive/capsulated/ bile soluble - C. Gram positive cocci / ß-hemolytic, capsulated/ Optochin resistant/ Bile soluble - D. Gram positive diplococci / alpha-hemolytic, capsulated/ Optochin sensitive/ Bile soluble 3. Identify the bacteria which is oxidase-positive? - A. Staphylococcus - B. Streptococcus - C. Neisseria - D. Corynebacterium 4. Bacteria which produces coagulase enzyme is - A. *Staphylococcus aureus* - B. *S saprophyticus* - C. *S. epidermidis* - D. All species of *staphylococci* 5. Staphylococcal food poisoning usually manifests itself following ingestion of contaminated food after - A. 2-6 hours - B. 8-12 hours - C. 12-18 hours - D. 18-36 hours 6. The bacteria which is novobiocin resistant is - A. *Staphylococcus aureus* - B. *S epidermidis* - C. *S saprophyticus* - D. None of the answers is correct 7. The toxin of *Staphylococcus aureus* that may result into scalded skin syndrome is - A. Enterotoxin - B. Leucocidin - C. Exfoliatin - D. Haemolysin 8. Protein A is found in cell wall of - A. Coagulase-negative staphylococci - B. *Staphylococcus aureus* - C. *S epidermidis* - D. *Streptococcus pyogenes* 9. Medusa head appearance of the colonies on blood agar may be due to - A. *Bacillus anthracis* - B. *Neisseria gonorrheae* - C. *Clostridium tetani* - D. *Streptococcus pneumoniae* 10. Food most often associated with food poisoning caused by *Bacillus cereus*, is - A. Meat - B. Rice - C. Milk - D. Eggs 11. Pseudomembraneous colitis is - A. precipitated by the use of certain antibiotics - B. caused by a gram-positive spore-forming bacterium - C. caused by *Clostridium difficile* - D. all answers are correct 12. The "A" subunit of diphtheria toxin - A. reversibly binds to target cells in heart and CNS - B. cause ADP ribosylation of a factor involved in protein synthesis - C. forms CAMP that leads to fluid accumulation - D. lysis macrophages with the release of cytokines 13. Which of the following disease is NOT caused by microbial toxin? - A. Botulism - B. Diphtheria - C. Anthrax - D. Erysipelas 14. Which of the following properties are the characteristics of tetanospasmin? - A. It causes tetanus - B. It is a neurotoxin - C. It can be toxoided - D. All answers are correct 15. *Clostridium botulinum* food poisoning in adults is due to - A. multiplication and invasion of bacteria in the intestine - B. multiplication and toxin production by bacteria in the intestine - C. preformed toxin - D. all answers are correct 16. Typical drumstick appearance of bacilli is generally seen in - A. *Clostridium perfringens* - B. *C. botulinum* - C. *C. tetani* - D. *C. defficile* 17. Which of the following condition is non-suppurative sequelae of *Streptococcus pyogenes* infections? - A. Acute rheumatic fever - B. Sore throat - C. Imptigo - D. Scarlet fever 18. *Streptococcus pyogenes* can be differentiated from other beta haemolytic Streptococci on the basis of - A. Bacitracin sensitivity - B. Erythromycin sensitivity - C. Aminoglycosides sensitivity - D. Penicillin sensitivity 19. Neonatal meningitis may be caused by: - A. *Staphylococcus aureus* - B. *Staphylococcus epidermidis* - C. *Streptococcus pyogenes* - D. *Streptococcus agalactiae* 20. Which injury does not predispose a person to gas gangrene? - A. Surgical incisions - B. Compound fractures - C. Dislocated shoulder - D. Diabetic ulcers