Lesson-4_NON-MENDELIAN.pdf

Learning Objectives I. Distinguish Mendelian from non-Mendelian modes of inheritance II. Describe some cases of non-Mendelian genetic traits ❖ RW ❖ 1 RR : 2 RW : 1 WW ❖ 1 RED : 2 PINK : 1 WHITE LET’S PRACTICE LET’S PRACTICE ALLELE NOTATION FOR CODOMINANCE...

Learning Objectives I. Distinguish Mendelian from non-Mendelian modes of inheritance II. Describe some cases of non-Mendelian genetic traits ❖ RW ❖ 1 RR : 2 RW : 1 WW ❖ 1 RED : 2 PINK : 1 WHITE LET’S PRACTICE LET’S PRACTICE ALLELE NOTATION FOR CODOMINANCE 1. Choose a letter to represent the gene. 2. Choose different letters to represent each of the alleles. 3. Take the letters representing the alleles and turn them into superscripts. 4. Combine the two. Remember to use capital letters. LET’S PRACTICE Tabby cats exhibit codominance between tan and black fur. 1.Can Tan Cat be heterozygous? Why or Why not? 2.If you mate a tabby with a black cat, what is the phenotypic ratio of their offspring? 3.If the offspring of two cats are composed of 36 tabbies and 40 black cats, what are the parental phenotypes and genotypes? MULTIPLE ALLELES When there are more than two types of alleles for a given locus or trait, this will result in more than two kinds of phenotypes that may be expressed for that trait. Can you donate A blood to a patient with type B blood? Ans: NO. The antigens would react with the A antibodies resulting in agglutination. |LET’S PRACTICE 1. Show a cross between a person who has heterozygous A type blood & a person who has homozygous B type blood. What are the possible blood types of their offspring? |LET’S PRACTICE 2. A man with type AB blood is married to a woman with type O blood. They have two children, and one adopted child. The children's blood types are: A, B, and O. Which child was adopted? |LET’S PRACTICE 1. Could a man with AB blood have an AB child with a woman with type O blood? 2. If a child has type B blood, what are all the possible blood types for his/her parents? 3. A paternity test is being performed. The child has type A blood. The mother is type A. Potential Dad #1 has type B blood. Potential Dad #2 has type O blood. Who is the father? Challenge: What two parents could produce the most diverse children as far as blood type is concerned? IAi x IBi → Type A, B, AB, O  CHINCHILLA AGOUTI HIMALAYAN ALBINO  | MULTIPLE ALLELES: Coat Color in Rabbit AGOUTI CHINCHILLA Agouti HIMALAYAN ALBINO |LET’S PRACTICE 1. What is the offspring of a cross between an agouti (Ccch) and a chinchilla (cchch)? Identify the GR and PR. GR: 1Ccch : 1 Cch : 1 cchcch : 1 cchch PR: 1agouti : 1 chinchilla 2. Show a cross between a chinchilla (cchc) and a himalayan (chc). Identify the GR and PR. LETHAL GENES Ex. In mice, yellow coat color is dominant to grey Mice that have YY (pure yellow) coat color do not survive |LET’S PRACTICE Cross hybrid yellow mice Yy x Yy. Identify the GR and PR.