Lesson-3-BLOOD.pdf

Biochemistry (MC2 Lec) Lesson 3 BLOOD Adapted from for Easter College 3  3.1: Introduction Blood: Blood cells: Is connective tissue Form mostly in red Transports vital...

Biochemistry (MC2 Lec) Lesson 3 BLOOD Adapted from for Easter College 3  3.1: Introduction Blood: Blood cells: Is connective tissue Form mostly in red Transports vital bone marrow and are: substances Red blood cells (RBCs) Maintains stability of White blood cells interstitial fluid (WBCs) Distributes heat Platelets (cell fragments) The amount of blood varies with body size, changes in fluid concentration, changes in electrolyte concentration, and amount of adipose tissue Blood is about 8% of body weight Adult blood volume is about 5 liters 4  Blood is 45% cells – This is also known as the hematocrit or percent packed cell volume – 99% are red blood cells, remainder white blood cells and blood platelets – The hematocrit is an indicator of anemia, polycythemia, and other conditions. Blood is 55% plasma – water, amino acids, proteins, carbohydrates, lipids, vitamins, hormones, electrolytes, wastes  Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Centrifuged Blood Sample Liquid (plasma) “Buffy coat” (white blood cells and platelets) Red blood cells Peripheral Blood Smear White blood cells Red blood cells 5 Platelets  Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Capillary tube Plasma = 55% Buffy coat Red cells = 45% (hematocrit) Plug 5  Blood 45% 55% Formed Plasma elements Platelets Red blood White blood Electrolytes Water Proteins Wastes Nutrients Gases (4.8%) cells cells (92%) (7%) (95.1%) Vitamins (0.1%) Hormones Neutrophils Eosinophils Basophils Monocytes Lymphocytes Albumins Globulins Fibrinogen N2 O2 CO2 (54–62%) (1–3%) (