Summary

These lecture notes provide an overview of marijuana, touching on its psychopharmacological aspects, various strains, and potential medicinal uses. The notes also discuss the historical context of marijuana use and explore its impact in different contexts.

Full Transcript

Psychopharmacology Marijuana Marijuana:Introduction Marijuana: An Introduction Psychoactive product of Cannabis plant Remarkably difficult 4.0% of world’s Remarkably hardy drug: drug to classify- it’s population uses...

Psychopharmacology Marijuana Marijuana:Introduction Marijuana: An Introduction Psychoactive product of Cannabis plant Remarkably difficult 4.0% of world’s Remarkably hardy drug: drug to classify- it’s population uses Grows everywhere! in a league of its own! cannabis annually BIG Money! Almost 20 Billion Dollars in Legal Sales Alone in 2020. Marijuana: Use in the USA But Much More Potent: 10% to 12% compared to 2% potency in 1980 If You are Ever in Amsterdam… Origin: The Cannabis Plant The Cannabis plant has three recognized varieties, all quite similar. Hemp Fibers have been used for over 50000 years Species? Subspecies? Strains? Varieties? Hemp (C. ruderalis) is a major industrial product worldwide. Distinguishing Factor is THC Content (Hemp at no more than 0.3% THC by dry weight, marijuana has up to 30% THC content. Marijuana: Two Varieties (Maybe?) Serrated leaves form basis for pot. ❖ Over 400 different chemical compounds ❖ Over 85 different cannabinoids, including ❖THC: delta-9-tetrahydrocannabinol ❖CBD: Cannabidiol ❖Strains differ on relative proportion of each Examples THC CBD Use Cannabis sativa High THC 10-30% Trace Amount Recreational Cannabis indica ❖Higher THC:CBD ratio ❖Higher CBD:THC ratio Balanced 5-15% 5-15% Medical with ❖Better high, greater anxiety. slight buzz ❖Greater sedative power, ❖Source of traditional lesser anxiety. recreational pot High CBD < 5% 5-20% Medical ❖Basis for medicinal strains Many medicinal and recreational strains are a mixture of the varieties. Marijuana: Different Strains, Different Forms Form Image THC level Marijuana: dried and DEA Seizures 1995 2014 shredded leaves and flowers THC 4% 12% CBD 0.28%

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