Pharmaceutical Organic Chemistry I (PMC 102) Lecture Notes PDF

Pharmaceutical Organic Chemistry I (PMC 102) Dr. Asmaa Yassen gu.edu.eg Course Name: Pharmaceutical Organic Chemistry I 3 Cr. Hrs. = (2 LCT + 2 LAB ) Course Code : PMC 102 Grade: Final exam (40) Mid Term Exam (10) Prac...

Pharmaceutical Organic Chemistry I (PMC 102) Dr. Asmaa Yassen gu.edu.eg Course Name: Pharmaceutical Organic Chemistry I 3 Cr. Hrs. = (2 LCT + 2 LAB ) Course Code : PMC 102 Grade: Final exam (40) Mid Term Exam (10) Practical Exam (30) Course Activity (20)  01 INTRODUCTION Basic Principles  CONTENTS OF THIS LECTURE 1. What is organic chemistry? 2. Why do we study organic chemistry? 3. Carbon atom 4. Electronegativity 5. Types of Chemical bonds 6. Molecular formula and structural formula 7. Functional groups 8. Types of Carbon 9. Isomers 10.Nucleophiles &Electrophiles 11.Formal Charge and Partial charge 12.Intermolecular forces 13.Types of Reactions 14.Hybridization  What is Organic Chemistry? It is the branch of Chemistry which deals with the carbon Compounds.  Why do we study Organic Chemistry? Organic Chemistry is the basis for life. Organic Chemicals are all around us, are what you are made of.  Atom consists of: a) Nucleus: (containing Protons and Neutrons) Protons (positive particles, Atomic Number) Neutrons (Neutral particles) Protons + Neutrons (Atomic weight) b) Electrons: negatively charged particles Orbital Shape Carbon Atom  Electronegativity It is the ability of an atom to attract electrons toward itself.  Types of Chemical Bonds Ionic Bond It is formed by the transfer of one or more valence electrons from one atom to another  Types of Chemical Bonds Covlaent Bond It is formed when two atoms share one or more electron pairs.  Types of Covalent Bond Depends on electronegativity. Non-Polar Covalent Bond The bond between 2 atoms of same EN or near to each other  Types of Covalent Bond Depends on electronegativity. Polar Covalent Bond Formed on the difference in EN is