Pharmaceutical Solutions - Lecture Notes PDF

### Question Preview **What are the disadvantages of pharmaceutical non-aqueous solutions over aqueous solutions?** * **Flexibility in drug delivery** * **Reduce solubility range of drugs** * **Lower drug stability** * **Increased cost for formulations** **What defines a pharmaceutical solution?*...

### Question Preview **What are the disadvantages of pharmaceutical non-aqueous solutions over aqueous solutions?** * **Flexibility in drug delivery** * **Reduce solubility range of drugs** * **Lower drug stability** * **Increased cost for formulations** **What defines a pharmaceutical solution?** * **A mixture of a solute dissolved in a solvent, resulting in a clear solution** * **A mixture of two or more substances without a solvent** * **A mixture requiring shaking before administration** * **A mixture with no advantages or disadvantages** **Which of the following is NOT an advantage of pharmaceutical solutions?** * **Enhanced palatability and ease of administration** * **Rapid onset of action compared to solid dosage forms** * **Homogeneous dosage delivery without the need for additional steps** * **Enhanced stability over time** **Which method is used to prepare purified water for pharmaceutical use?** * **Ion exchange** * **All answers are correct** * **Reverse osmosis** * **Distillation** **Which of the following is an advantage of using the distillation process to prepare purified water?** * **Chemical free method** * **All answers are correct** * **Simple method** * **Energy-intensive method** **Which method is used to obtain demineralized water for pharmaceutical use?** * **All answers are correct** * **Reverse Osmosis method** * **Ion exchange method** * **Distillation method** **What is the primary function of aromatic waters in pharmaceutical solutions?** * **To resist the change in pH** * **To enhance the stability** * **To mask unpleasant odors and provide flavors** * **To increase viscosity** **What is the purpose of preservatives in pharmaceutical solutions?** * **To enhance the palatability** * **To prevent the microbial contamination** * **To increase the viscosity** * **To resist the change in pH** **True or False: The solution process for aromatic water involves heating the plant material with water to produce the volatile aromatic compounds.** * **True** * **False** **True or False: Nasal solutions are primarily intended for long-term use to relieve nasal congestion without the risk of rebound congestion** * **True** * **False** **True or False: Sucrose is the sugar most frequently used in syrups due to its purity sweetness, and lack of colour.** * **True** * **False** **True or False: Elixirs are hydro-alcoholic solutions, and poorly water-soluble ingredients require a higher proportion of alcohol.** * **False** * **True** **True or False: Spirits contain fewer volatile substances than aromatic water due to the low alcohol content in their composition** * **True** * **False** **True or False: Microbial Contamination Testing in quality control is performed to ensure that the solution is free from harmful microorganisms and contaminants.** * **False** * **True** **True or False: Stability studies in quality control aim to determine the shelf-life and stability of a solution over a short period?** * **True** * **False** **Reverse osmosis removes particles smaller than 0.001 microns; virtually all virus, bacteria, pyrogens, organic molecules** * **True** * **False** **Give name: The method involving the heating and cooling process to obtain highly purified water** * Answer: **Distillation** **Give name: Oleaginous Solutions used for direct topical application with massage to relieve pain and discomfort in muscles and joints** * Answer: **Liniments** **Which method is used to prepare purified water for pharmaceutical use?** * **All answers are correct** * **Ion exchange** * **Distillation** * **Reverse osmosis** **True or False: Distillation is an energy-intensive process used for the preparation of purified water in pharmaceutical applications.** * **False** * **True** **True or False: Nasal solutions are primarily intended for long-term use to relieve nasal congestion without the risk of rebound congestion.** * **True** * **False** **Which of the following is an advantage of using the distillation process to prepare purified water?** * **All answers are correct** * **Chemical free method** * **Simple method** * **Energy-intensive method** **Which method is used to obtain demineralized water for pharmaceutical use?** * **Ion exchange method** * **Distillation method** * **Reverse Osmosis method** * **All answers are correct** **True or False: Spirits contain fewer volatile substances than aromatic water due to the low alcohol content in their composition** * **False** * **True** **Which of the following is NOT an advantage of pharmaceutical solutions?** * **Rapid onset of action compared to solid dosage forms** * **Homogeneous dosage delivery without the need for additional steps** * **Enhanced palatability and ease of administration** * **Enhanced stability over time** **What are the disadvantages of pharmaceutical non-aqueous solutions over aqueous solutions?** * **Reduce solubility range of drugs** * **Lower drug stability** * **Increased cost for formulations** * **Flexibility in drug delivery** **True or False: Elixirs are hydro-alcoholic solutions, and poorly water-soluble ingredients require a higher proportion of alcohol.** * **True** * **False** **Reverse osmosis removes particles smaller than 0.001 microns; virtually all virus, bacteria, pyrogens, organic molecules** * **True** * **False** **True or False: Stability studies in quality control aim to determine the shelf-life and stability of a solution over a short period?** * **False** * **True** **True or False: Sucrose is the sugar most frequently used in syrups due to its purity sweetness, and lack of colour.** * **True** * **False** **What defines a pharmaceutical solution?** * **A mixture requiring shaking before administration** * **A mixture of two or more substances without a solvent** * **A mixture of a solute dissolved in a solvent** * **resulting in a clear solution** **What is the primary function of aromatic waters in pharmaceutical solutions?** * **To increase viscosity** * **To enhance the stability** * **To resist the change in pH** * **To mask unpleasant odors and provide flavors** **True or False: Potable water is suitable for pharmaceutical compounding due to its purity and safety for consumption.** * **True** * **False** **True or False: Microbial Contamination Testing in quality control is performed to ensure that the solution is free from harmful microorganisms and contaminants.** * **False** * **True**