L2 QS BANK, BMS201 PDF

Part One: Simple MCQs 1. What is the normal shape of red blood cells (RBCs) as seen in a stained blood smear? a) Biconvex discs b) Biconcave discs c) Spherical d) Sickle-shaped 2. What is the average diameter of a normal RBC? a) 4-5 μm b) 6-9 μm c) 10-12 μm d) 13-15 μm 3. Which of the following...

Part One: Simple MCQs 1. What is the normal shape of red blood cells (RBCs) as seen in a stained blood smear? a) Biconvex discs b) Biconcave discs c) Spherical d) Sickle-shaped 2. What is the average diameter of a normal RBC? a) 4-5 μm b) 6-9 μm c) 10-12 μm d) 13-15 μm 3. Which of the following conditions is associated with RBCs larger than 9 μm in diameter? a) Microcytic anemia b) Macrocytic anemia c) Spherocytosis d) Sickle cell disease 4. What is the function of the network of proteins (spectrin, ankyrin, and actin) in the RBC membrane? a) Gas exchange b) Oxygen transport c) Support and flexibility d) Blood clotting 5. What is the main component of the RBC cytoplasm? a) Mitochondria b) Hemoglobin c) Nucleus d) Ribosomes 6. How long is the average lifespan of an RBC? a) 30 days b) 60 days c) 120 days d) 240 days 7. Which cells are responsible for removing dead or worn-out RBCs from circulation? a) Neutrophils b) Lymphocytes c) Macrophages d) Eosinophils 8. What is the term for the process of blood cell formation? a) Erythropoiesis b) Hemopoiesis c) Hemolysis d) Phagocytosis 9. All blood cells are derived from which type of cell? a) Pluripotential hemopoietic stem cell b) Myeloid stem cell c) Lymphoid stem cell d) Progenitor cell 10. What is the first precursor (blast cell) of RBCs? a) Reticulocyte b) Orthochromatophilic erythroblast c) Proerythroblast d) Basophilic erythroblast ANSWERS Part One 1. b 2. b 3. b 4. c 5. b 6. c 7. c 8. b 9. a 10. c Part Two: Complex MCQs 1. How does the biconcave shape of RBCs facilitate gas exchange? a) It increases the cell's volume b) It reduces the cell's surface area c) It increases the cell's surface area d) It makes the cell less flexible 2. What is the significance of RBCs lacking a nucleus and cell organelles? a) It allows them to divide more rapidly b) It enables them to carry more hemoglobin c) It makes them more susceptible to damage d) It increases their lifespan 3. In sickle cell disease, what is the consequence of the abnormal shape of RBCs? a) Increased flexibility and longer lifespan b) Decreased flexibility, fragility, and shorter lifespan c) Enhanced oxygen-carrying capacity d) Reduced blood viscosity 4. What is the clinical significance of reticulocytosis (increased reticulocytes in blood)? a) It indicates normal RBC production b) It suggests decreased RBC production c) It indicates increased RBC production, often in response to blood loss or hemolysis d) It is a sign of iron deficiency 5. What are Romanowsky stains used for in histology? a) Staining bone tissue b) Staining muscle tissue c) Staining blood cells d) Staining nerve tissue 6. What is the difference between a myeloid stem cell and a lymphoid stem cell? a) Both give rise to all types of blood cells b) Myeloid stem cells give rise to RBCs, WBCs, and platelets, while lymphoid stem cells give rise to lymphocytes c) Lymphoid stem cells give rise to RBCs, WBCs, and platelets, while myeloid stem cells give rise to lymphocytes d) They are both types of progenitor cells 7. Describe the changes in the nucleus and cytoplasm during erythropoiesis. a) The nucleus becomes larger and the cytoplasm becomes more basophilic b) The nucleus becomes smaller and eventually extruded, and the cytoplasm changes from basophilic to acidophilic c) The nucleus remains unchanged, and the cytoplasm becomes less basophilic d) The nucleus divides multiple times, and the cytoplasm becomes granular 8. What is the function of antigens on the RBC membrane? a) Gas exchange b) Oxygen transport c) Determining blood type d) Cell flexibility 9. Why is the flexibility of the RBC membrane important? a) It allows RBCs to adhere to each other in stacks b) It facilitates the removal of old RBCs by macrophages c) It enables RBCs to pass through small capillaries without rupturing d) It helps maintain blood viscosity 10. What happens to the hemoglobin released from ruptured RBCs? a) It is excreted in the urine b) It is phagocytosed by macrophages c) It is converted to bilirubin in the bloodstream d) It is reused to form new RBCs 11. Which stain is a mixture of acidic and basic dyes? a) Leishman's stain b) Giemsa stain c) Wright stain d) Romanowsky stain 12. What are the two types of progenitor cells derived from the pluripotential hemopoietic stem cell? a) Myeloid stem cell and lymphoid stem cell b) Proerythroblast and reticulocyte c) Neutrophil and lymphocyte d) Macrophage and platelet 13. In which stage of erythropoiesis does hemoglobin synthesis begin? a) Proerythroblast b) Basophilic erythroblast c) Polychromatophilic erythroblast d) Orthochromatophilic erythroblast 14. What is the characteristic feature of a reticulocyte? a) It has a nucleus b) It has no ribosomes c) It has a reticulum of ribosomal RNA d) It is fully mature 15. What is the normal concentration of RBCs in blood for females? a) 3.9- 5.5 million/ μL b) 4.1- 6.0 million/ μL c) 6-9 million/ μL d) 10-12 million/ μL Answer Guide Part Two 1. c 2. b 3. b 4. c 5. c 6. b 7. b 8. c 9. c 10. b 11. a 12. a 13. b 14. c 15. a Done