GI Medication List PDF

Summary

This document contains a list of frequently used GI medications, including their mechanisms of action, adverse effects, and indications. It's likely a study resource for medical students or professionals studying gastrointestinal medicine and pharmacology.

Full Transcript

1. What is the mechanism of action of amoxicillin/clavulanate? a) Inhibits DNA synthesis b) Inhibits bacterial cell wall synthesis and protects against beta-lactamase c) Binds to 50S ribosomal subunit d) Disrupts bacterial RNA synthesis Answer: b) Inhibits bacterial cell wall synthesis and protects...

1. What is the mechanism of action of amoxicillin/clavulanate? a) Inhibits DNA synthesis b) Inhibits bacterial cell wall synthesis and protects against beta-lactamase c) Binds to 50S ribosomal subunit d) Disrupts bacterial RNA synthesis Answer: b) Inhibits bacterial cell wall synthesis and protects against beta-lactamase 2. Which adverse effect is commonly associated with ciprofloxacin? a) Hyperkalemia b) QT prolongation c) Rash d) Hepatotoxicity Answer: b) QT prolongation 3. What is a contraindication for levofloxacin use? a) Sulfa allergy b) Myasthenia gravis c) Chronic kidney disease d) Pregnancy Answer: b) Myasthenia gravis 4. What is the primary indication for azithromycin? a) UTIs b) Respiratory tract infections c) Gram-negative sepsis d) Hepatic encephalopathy Answer: b) Respiratory tract infections 5. Which antibiotic is a beta-lactam/beta-lactamase inhibitor combination? a) Piperacillin/tazobactam b) Vancomycin c) Azithromycin d) Ceftriaxone Answer: a) Piperacillin/tazobactam 6. Which adverse effect is associated with trimethoprim/sulfamethoxazole? a) Nephrotoxicity b) Hyperkalemia c) QT prolongation d) Tendon rupture Answer: b) Hyperkalemia 7. What is the mechanism of action of ceftriaxone? a) Inhibits bacterial cell wall synthesis b) Inhibits DNA gyrase c) Inhibits folate metabolism d) Inhibits RNA synthesis Answer: a) Inhibits bacterial cell wall synthesis 8. Which antibiotic is most effective against anaerobic bacteria? a) Cefotaxime b) Metronidazole c) Ciprofloxacin d) Azithromycin Answer: b) Metronidazole 9. What is the primary indication for vancomycin oral therapy? a) MRSA infections b) Clostridium difficile infections c) Pseudomonas infections d) Community-acquired pneumonia Answer: b) Clostridium difficile infections 10. Which antibiotic inhibits bacterial RNA polymerase? a) Rifaximin b) Fidaxomicin c) Ciprofloxacin d) Levofloxacin Answer: b) Fidaxomicin 11. What is the primary adverse effect of metronidazole? a) Peripheral edema b) Metallic taste c) Ototoxicity d) Hyperkalemia Answer: b) Metallic taste 12. Which antibiotic is used to treat hepatic encephalopathy? a) Rifaximin b) Vancomycin c) Piperacillin/tazobactam d) Azithromycin Answer: a) Rifaximin 13. What is a black-box warning for fluoroquinolones like ciprofloxacin? a) QT prolongation b) Tendon rupture c) Hepatotoxicity d) Hypokalemia Answer: b) Tendon rupture 14. Which antibiotic combination includes a beta-lactamase inhibitor? a) Amoxicillin/clavulanate b) Ciprofloxacin/metronidazole c) Azithromycin/cefotaxime d) Vancomycin/rifaximin Answer: a) Amoxicillin/clavulanate 15. What is the mechanism of action of trimethoprim/sulfamethoxazole? a) Inhibits protein synthesis b) Inhibits folate metabolism c) Inhibits bacterial cell wall synthesis d) Disrupts DNA synthesis Answer: b) Inhibits folate metabolism 16. What is a significant adverse effect of vancomycin IV therapy? a) Hepatotoxicity b) Nephrotoxicity c) Hyperkalemia d) Hypocalcemia Answer: b) Nephrotoxicity 17. Which antibiotic requires monitoring of trough levels? a) Vancomycin b) Azithromycin c) Ceftriaxone d) Ciprofloxacin Answer: a) Vancomycin 18. What is a common interaction for metronidazole? a) Increased warfarin toxicity b) Decreased ciprofloxacin absorption c) Hyperkalemia with ACE inhibitors d) QT prolongation with fluoroquinolones Answer: a) Increased warfarin toxicity 19. What is the primary adverse effect of fidaxomicin? a) Rash b) Anemia c) Peripheral neuropathy d) Photosensitivity Answer: b) Anemia 20. What is the mechanism of action of piperacillin/tazobactam? a) Inhibits protein synthesis b) Inhibits bacterial cell wall synthesis and protects against beta-lactamase c) Inhibits DNA gyrase d) Disrupts bacterial RNA polymerase Answer: b) Inhibits bacterial cell wall synthesis and protects against beta-lactamase

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