Drug Information PDF

Generic Name Commo n Bran Therape Pharm Route(s Contraindi d utic acologi ) of cations Name Class c Class Adminis tration Shortacting Inhaled beta agonist Albuterol Boxed Warnings and Precautions Clinically Relevant Counsel Adverse ing Reactions Points (ADRs) none Tremor, paradoxical nervousn...

Generic Name Commo n Bran Therape Pharm Route(s Contraindi d utic acologi ) of cations Name Class c Class Adminis tration Shortacting Inhaled beta agonist Albuterol Boxed Warnings and Precautions Clinically Relevant Counsel Adverse ing Reactions Points (ADRs) none Tremor, paradoxical nervousness bronchospasm , tachycardia none StevensJohnson syndrome, toxic epidermal necrolysis, hepatotoxicity, immune hypersensitivit y reaction, renal failure Prove ntil HFA, Ventol in HFA, ProAir Respi click, ProAir Respirat Digiha ory Tract ler Agents Antigout Allopurinol Zylopr im Oral Xanthin e Oxidas e Inhibitor worsening gout at first, maculopapul ar rash This is a rescue inhaler and should be used as needed for symptom s. Counsel on appropri ate inhaler techniqu e: Respiclic k and Digihaler - do not shake, inhale deeply and quickly vs HFAshake well before use and inhale slowly. take after meals to lessen gastric irritation, maintain adequat e hydratio n to prevent kidney stones, avoid alcohol and caffeine Antihista Antihist Nasal mine amine none none avoid spraying in eyes, somnole nce has been reported with nasal administ ration, instruct patient to avoid alcohol use and hazardo us activities until level of sedation is known, may bitter taste cause in mouth, taste headache, disturba somnolence nces Azelastine Astep ro, Asteli n Baclofen Avoid stopping abruptly. Can BOXED cause WARNING: dizzines Abrupt s and withdrawal Weakness, drowsine Injecting IV, especially with Skeletal dizziness, ss. Skeletal Oral, IM, SubQ, the intrathecal Muscle vertigo, Contact Muscle Intrathec or epidural route. Relaxa drowsiness, your Relaxant al administrati Precaution: nt withdraw physicia on Avoid in syndrome n if patients with mental, psychiatric mood, or and seizure behavior disorders changes that are Liores new or al worse. Inhaled none Pulmi cort Resp ules, Pulmi cort Respirat Inhaled Budesonid Flexh ory Tract Cortico e aler Agents steroids Inhaled Combin ation: Inhaled Cortico steroids + LongBudesonid Respirat acting e/Formoter Symbi ory Tract beta ol cort Agents agonist Carisoprod ol Soma Skeletal Skeletal Muscle Muscle Oral Relaxa Relaxant nt none Rinse mouth and spit after each use. This May cause a is a reduction in mainten growth ance velocity in inhaler pediatric Oral and patients, candidiasis, should increased risk hoarseness be used of pneumonia routinely, in COPD regardle patients, ss of paradoxical symptom bronchospasm s. Do not shake, inhale deeply and quickly. May cause a reduction in growth velocity in pediatric patients, increased risk of pneumonia in COPD patients, paradoxical bronchospasm Precaution: CNS Hypersensiti depression: vity to may impair carbamates physical or mental abilities; Oral candidiasis, hoarseness, tremor, nervousness Dizziniess, drowsiness, headache, rare but serious: seizures Rinse mouth and spit after each use. Shake well before use and inhale slowly. This may be used as mainten ance therapy only or as mainten ance and rescue therapy. If you notice a new blistering rash, stop therapy concomitant use of other CNS depressants Acute intermittent porphyria Precaution: Seizures Do not drive or operate machine ry until you know how this medicati on will affect you Celeb rex High blood pressure can occur BOXED when WARNING: taking Serious this drug cardiovascular There risk has - Including been an myocardial associat infarction (MI), Acute ed and stroke, kideny incrreas which can be injury, e in fatal. increased heart BOXED brusing or attacks WARNING: bleeding, GI and Serious upset (less strokes gastrointestina than other when l events NSAIDs) taking - Including medicait bleeding, ons like ulceration, and this one. perforation of You may the stomach bleed or intestines, more which can be easly fatal when taking ths medicati on (Vario Clobetasol us) apply a thin layer to affected area of skin, wash hands after administr Analgesi c (Pain Medicati on) Celecoxib COX-2 Selectiv e antiOral inflama mtory agent CYP2C9 Substrate Hypersensiti vity (eg, anaphylaxis , serious skin reactions) to celecoxib, sulfonamide s, aspirin, other NSAIDs. Though Sulfa cross reactivity is questionabl e Cream, Corticost Topical Ointmen None eroid Steroid t, Solution None pruritis ation, skin should be clean and intact at site of administr ation Antigout Colchicine Oral Uricosu ric Agents Colcry s Skeletal Skeletal Muscle Muscle Oral Relaxa Relaxant nt Cyclobenza Flexer prine il Gastroint Proton estinal Pump Oral agent Inhibitor The concomitant use of a Pglycoprotein or CYP3A4 inhibitor and colchicine in the presence of renal or hepatic impairment is contraindica ted MAOi inhibitors, arrhythmias; heart block or conduction disturbance s; acute recovery phase of MI, avoid iin patient's with heart failure Biliary obstruction, renal impairment, hepatic disease, and renal disease Diclofenac Voltar en Nonsteroida l antiinflamm atory agent Oral, Topical instruct patient on appropri ate dosing strategy for gout flares No boxed warnings, risk for arrhythmias and QTc prolongation, risk for serotonin syndrrome - Monitor for Anticholener drowsiin gic side ess and effectssedation, urinary monitorr hesitancy, for constipation, abnorma dizziness, l drowsineess heartbea t None None Stomach pain and diarrhea, C. difficile diarrhea, hypomagne semia Best to take 30 minutes before food/drin k in the morning, History of asthma, urticaria, or other allergic-type reactions after taking aspirin or other BOXED WARNING: Serious cardiovascular risk - Including myocardial infarction (MI), and stroke, Acute kideny injury, increased brusing or bleeding, GI upset (less than other NSAIDs), High blood pressure can occur when taking this drug You may Dexlansopr Dexila azole nt Analgesi c (Pain Medicati on) GI issues (diarrhea, vomiting, nausea) nonsteroidal antiinflammator y drugs which can be increased fatal. liver BOXED enzymes WARNING: Serious Major gastrointestina substrate of l events CYP2C9 - Including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal" Obstructive diseases of the GI tract Severe ulcerative colitis Reflux esophagitis Antichol Antispa Oral, obstructive energic smodic Intramus uropathy; agent Agent cular glaucoma; myasthenia gravis; breastfeedin g women; infants <6 months of age No boxed warnings, Psychosis/deli rium: In patients with an extreme sensitivity to anticholinergic effects or at excessive dosages, such as the elderly or patients with mental illness. Anticholener gic side effectsurinary hesitancy, constipation, dizziness, drowsineess Tachycardia Dicyclomin e Bentyl Gastroin Antidiar Diphenoxyl estinal Oral rheal ate/Atropin Lomot agent e il Hypersensit vity to drug or it components , Flushing, No boxed tachycardia, warnings confusion Atropinism abdominal CNS dression distress bleed more easly when taking ths medicati on Contact medical help if you experien ce darking of urine or yellowin g of eyes Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this drug affects you. Contact a provider if you feel like you or a loved one notice more confusio n Pancrea s problem (pancrea titis) like objstructive Slow GI jaundice, C mobility diff diareha Gastroint Proton estinal Pump Oral Agent Inhibitor None None Esomepraz Nexiu ole m Etodolac NonAnalgesi Lodin steroida Oral c (Pain e l anti- Hypersensiti BOXED vity (eg, WARNING: anaphylaxis Serious very bad stomach pain, very bad back pain, or very bad upset stomach or throwing up Avoid driving and doing other tasks or actions that call for you to be alert until you see how this drug affects you. •Keep away from children. Accident al exposur e and overdos e may result in very bad breathin g problem s or coma Abdominal pain, C Diff diarrhea, headache, hypomagne semia, Best to take 30 minutes before food/drin k in the morning, Acute kideny injury, High blood pressure Medicati inflamm on) atory agent , serious skin reactions) to etodolac, aspirin, other NSAIDs. cardiovascular risk - Including myocardial infarction (MI), and stroke, which can be fatal. BOXED WARNING: Serious gastrointestina l events - Including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal increased brusing or bleeding, GI upset (less than other NSAIDs), pancreatitis, increase liver enzymes Not box warning: Risk for Steven Johnson Syndrome (SJS) or drug reaction with eosinophilia and systemic symptoms (DRESS) Histami ne-2 (H2) Recept Oral or Antago nist Xanthin Antigout e Oral Febuxostat Uloric Oxidas Pepci d, Pepci Antacid d AC, Zanta Famotidine c 360 None None Constipation , diarrhea, nausea, skin rash can occur when taking this drug You may bleed more easly when taking ths medicati on Contact get medical help if you experien ce darking of urine, yellowin g of eyes, extreme upper quadrant pain If you notice a new rash, swollen lymph nodes, fever, rash, joint pain, or lungs contact a provider e Inhibitor Significant respiratory depression Gastrointest inal obstruction, including paralytic ileus (known or suspected) Patch, Patients injection, requiring buccal, short-term sublingu therapy, al, nasal manageme nt of acute or intermittent pain, postoperativ e or mild pain; patients who are not opioid tolerant. Analgesi c (Pain Medicati on) Durag Fentanyl esic, Transderm Ionsy al s Opioid analges ic Topical Corticost Cortico eroid steroid Fluocinonid e Topical Lidex none cream, ointmen t, solution, gel BOXED WARNINGS: Life threatening respratory depression Abuse, addiction, and misuse Accidental exposure Cytochrome P450 CYP3A4 interactions Neonatal opioid withdrawal syndrorme Concomitant use of opioids with benzodiazepin es or other CNS depressants Substantial differences exist in the pharmacokinet ic profile of fentanyl buccal, intranasal, lozenge, and sublingual REMS program Exposure to heat (patch only) Take only as prescrib ed, this medcatio n is only for you and you alone to take. Keep in a safe place Constipation and out Respiratory of reach depresson of Opioid children withdrawal or pets. CNS Avoid depression driving Dependence and doing other tasks or actions that call for you to be alert until you see how this drug affects you. none None apply thin layer to affected area of skin, skin should be clean and intact at site of applicati on, avoid contact with eyes and do not ingest by mouth, avoid occlusiv e dressing s or tightfitting clothes over site of administ ration Inhaled Arnuit y Ellipta , Flove nt HFA, Flove nt Respirat Inhaled Fluticasone Disku ory Tract Cortico Oral Inhaler s Agents steroids none Rinse mouth and spit after each use. Digihaler , Diskus, Ellipta: Do not shake, May cause a inhale reduction in deeply growth and velocity in Oral quickly. pediatric candidiasis, HFApatients, hoarseness, Shake increased risk paradoxical well of pneumonia bronchospa before in COPD sm use and patients, inhale paradoxical slowly. bronchospasm This is a mainten ance inhaler and should be used routinely, regardle ss of symptom s. May cause a reduction in growth velocity in pediatric patients, increased risk of pneumonia in COPD patients, paradoxical bronchospasm Inhaled none Oral BOX WARNING: Addiction, abuse, and misuse Significant REMS respiratory program depression Life Gastrointest threatening inal respiratory obstruction, depression including Accidental paralytic Ingestion ileus Neonatal (known or opioid suspected) withdrawal syndrome Cytochrome P450 3A4 interactions Risk from Combin ation: Inhaled Cortico Advair steroids Disku + Longs, Respirat acting Fluticasone Advair ory Tract beta /Salmeterol HFA Agents agonist Analgesi c (Pain Medicati on) Norco , Lorcet , Hydrocodo Vicodi ne n Opioid Analges ics Oral candidiasis, hoarseness, tremor, nervousness , paradoxical bronchospa sm Rinse mouth and spit after each use. Digihaler , Diskus, Respiclic k: Do not shake, inhale deeply and quickly. HFAShake well before use and inhale slowly. This is a mainten ance inhaler and should be used routinely, regardle ss of symptom s. Take only as prescrib ed, this medcatio n is only for you Constipation and you Respiratory alone to depresson take. Opioid Keep in withdrawal a safe CNS place depression and out Dependence of reach of children or pets. Avoid driving and concomitant use with benzodiazepin es or other CNS depressants Interaction with alcohol Analgesi c (Pain Medicati Indomethac Indoci on) in n Nonsteroida l antiinflamm atory agent Combin ation: Shortacting muscari nic Inhaled antagon ist + shortacting Comb beta ivent Respirat agonist Ipratropium Respi ory Tract /Albuterol mat Agents none Cream, Foam, Gel, None Shampo o Antifung al Agents Ketoconaz Nizor ole Topical al doing other tasks or actions that call for you to be alert until you see how this drug affects you. imidazo les This may be used as mainten Tremor, ance nervousness therapy , only or paradoxical tachycardia, as bronchospasm bitter mainten metallic ance taste, and xerostomia rescue therapy. Breathe slowly. apply thin layer to affected area of skin, Skin skin irritation, should Hair loss be intact, with do not None shampoo, get it in application your site reaction eyes, with foam, nose, Rash mouth, or vagina, do not wash the areas where you applied this medicine for at least 3 hours after applicati on Lansoprazo Preva le cid Gastroint Proton estinal Pump Oral Agents Inhibitor None None Abdominal pain, C Diff diarrhea, headache, hypomagne semia, Take 30 minutes before food/drin k in the morning, This is a rescue inhaler and should be used as needed for symptom Shorts. Tremor, acting paradoxical Counsel Inhaled none nervousness beta bronchospasm on , tachycardia agonist appropri ate inhaler techniqu e: HFAshake well before Xope Respirat use and Levalbutero nex ory Tract inhale l HFA Agents slowly. instruct patients on the appropri ate Local applicati hypersensiti Asnesth Patch vity to None on etic (Topical) lidocaine process, (Pain) leave patches Skin on skin Lidocaine irritation, for no Topical Lidod Anesthet somnolence more Patch erm ics than 12 hours within a 24-hour period, caution patients to administ er only as directed, to intact skin, without covering with occlusiv e dressing or tight clothes Chlorid e Channe Oral l Activato r Gastroint Lubiproston Amitiz estinal Agent e a Hypersensiti vity, bowel obstruction Headache, nausea, diarrhea Hypotension, Syncope take with food and water to reduce risk of nausea, seek medical attention for chest pain, shortness of breath, or severe GI symptom s, dyspnea, described as chest tightness, has been reported and generally occurs with the 1st dose and resolves after a few hours without interventi on Hypersensiti vity to meloxicam; history of asthma, Nonurticaria, or Analgesi steroida other c (Pain l antiOral, allergic-type Medicati inflamm Injection reactions on) atory after taking agent aspirin or other nonsteroidal antiinflammator y drugs Not box warning: Risk for Steven Johnson Syndrome (SJS) , CYP2C9 substrate Meloxicam Mobic Skeletal Skeletal Muscle Muscle Relaxa Relaxant nt Skela Metaxalone xin BOXED WARNING: Serious cardiovascular risk - Including myocardial infarction (MI), and stroke, which can be fatal. BOXED WARNING: Serious gastrointestina l events - Including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal Oral High blood pressure can occur when taking this drug You may bleed Acute more kidney easly injury, when increased taking brusing or ths bleeding, GI medicati upset (less on than other If you NSAIDs), notice a increase new liver rash, enzymes swollen lymph nodes, fever, rash, joint pain, or lungs contact a provider If you start experien cing Significantly fever, impaired Dizziness/dr chills, hepatic or owsiness, sore renal Not box irritability/ner throat function warning: CNS vousness, contact a tendency to depression, Hemolytic provider drugserotonin anemia, You induced, syndrome leukopenia, might hemolytic liver enzyme noctice other elevations incrreas anemias ed sleepine ss and tiredness whle taking thisi medicati on BOXED WARNING: Addiction, abuse, misuse REMS program Life threatening respiratory depression QT prolongation Accidental ingestion Neonatal opioid Significant withdrawal respiratory syndrome depression Requires Oral, Gastrointest suprivision for Analgesi Opioid intraven inal detoxficaton c (Pain Analges ous, obstruction, and maintence Medicati ic intramus including for opioid on) cular paralytic dependence ileus CYP (known or interactions suspected) 3A4, 2B6, 2C19, 2C9, or 2D6 Concomitant use of opioid with benzodiazepin es or other CNS depressants Risk of medication errors 1 mg/mL soluation and Dolop 2 mg/mL Methadone hine solution Hypersensiti Oral, vity to Skeletal Skeletal intraven methocarba Muscle Muscle ous, mol or any Relaxa Relaxant intramus component nt Methocarb Roba cular of the amol xin formulation; Take only as prescrib ed, this medcatio n is only for you and you alone to take. Keep in a safe place Constipation and out Respiratory of reach depresson of Opioid children withdrawal or pets. CNS Avoid depression driving QTc and prologation doing other tasks or actions that call for you to be alert until you see how this drug affects you. renal impairment Intranas al Nasal Cortico steroid None None none BBW: neuropsychiatr ic events including agitation, aggression, depression, sleep disturbances, suicidal thoughts/beha vior headache, pharyngitis, nasal irritation & burning, Epistaxis Mometason Naso Corticost e Nasal nex eroids Leukotri ene recepto r Respirat pathwa Montelukas Singul ory Tract y t air Agents inhibitor Morphine Oral BOX WARNING: Monitor Significant patients for at respiratory least 24 hours depression Oral, IV, in a fully Gastrointest Analgesi intrathec equipped and inal c (Pain al, staffed obstruction, Medicati rectal, envirment if including MS on) subcuta giving paralytic Conti neous intrathecal or ileus n, epidural (known or Avinz Ethanol use suspected) a, Opioid Addition, Kadia Analges abuse, and n ics misuse headache, upper respiratory tract infections, nausea, vomiting, diarrhea shake well, advise patients on the proper administ ration techniqu e for this product, nasal spray needs to be primed before using and if not used for 1 week When used routinely for asthma, take at bedtime. Report any behavior al changes when taking. Take only as prescrib ed, this Constipation medcatio Respiratory n is only depresson for you Opioid and you withdrawal alone to CNS take. depression Keep in Pruritius a safe place and out of reach of Rems Medication Life threatening respiratory depression Neonatal opioid withdrawal syndrome Accidental ingestion Multiple ocnentratoins of the oral soluation Risk from concomitant use with benzodiazepin es or other CNS depressants Analgesi c (Pain Medicati on) Nabumeton Relaf e en Nonsteroida l antiOral inflamm atory agent children or pets. Avoid driving and doing other tasks or actions that call for you to be alert until you see how this drug affects you. High blood pressure can Hypersensiti BOXED occur vity to WARNING: when nabumeton Serious taking e or any cardiovascular this drug component risk You may of the - Including bleed formulation, myocardial Acute more urticaria, or infarction (MI), kidney easly allergic-type and stroke, injury, when reactions which can be increased taking after taking fatal. brusing or ths aspirin or BOXED bleeding, GI medicati other WARNING: upset (less on nonsteroidal Serious than other Contact antigastrointestina NSAIDs), a inflammator l events increase healthca y drugs - Including liver re (NSAIDs); bleeding, enzymes provider use in the ulceration, and if you setting of perforation of experien coronary the stomach ce liver artery or intestines, problem bypass graft which can be s like surgery. fatal dark urine, feeling tired, not hungry, upset stomach or stomach pain, lightcolored stools, throwing up, or yellow skin or eyes Take at least 30 minutes prior to food/drin k in the morning Gastroint Proton estinal Pump Oral Agent Inhibitor None Analgesi Opioid c (Pain Analges Oral Medicati ics on) Take only as BOXED prescrib WARNING: ed, this Addiction, medcatio abuse and n is only misuse for you REMS and you meication alone to Lifetake. threatening Keep in respiratory a safe Significant depresation place respiratory Accidental Constipation and out depression Injestion Respiratory of reach Gastrointest Neonatal depresson of inal opioid Opioid children obstruction, withdrawal withdrawal or pets. including Cytochrome CNS Avoid paralytic P450 3A4 depression driving ileus interaction Dependence and (known or Risk from doing suspected) concomitant other use with tasks or benzodiazepin actions es that call Risk of for you medication to be errors with alert until multiple you see formulations of how this the oxycodone drug affects you. Omeprazol Prilos e ec Oxyco Oxycodone ntin Abdominal pain, C Diff diarrhea, headache, hypomagne semia, None Gastroint Proton estinal Pump Oral Agent Inhibitor None None known or suspected bowel obstruction No boxed warnings Prolonged use may cause electrolyte disturbances Stop usng if diarrhea occurs Gastrointesti nal Abdominal pain and cramping, bloating and diarrhea Pantoprazo Proto le nix Gastroint Laxativ estinal Oral e Agent Polyethylen Golyt e Glycol ely Take at least 30 minutes prior to food/drin k in the morning It may take a few days to have full effects of ths medicato n Take at least 30 minutes prior to food/drin k in the morning take on an empty stomach and do not take any other medicati ons within 24 hours of sucralfat e, shake suspensi on well before use, suspensi on can be stored at room temperat ure Gastroint Proton estinal Pump Oral Agent Inhibitor None None Abdominal pain, C Diff diarrhea, headache, hypomagne semia, Gastroint Protect estinal Oral ant Agent None None Constipation none Respima t: Xerostomia, Breathe cough paradoxical slowly, bronchospasm Handihal Rabeprazol Aciph e ex Sucralfate Abdominal pain, C Diff diarrhea, headache, hypomagne semia, Caraf ate Spiriv Longa acting Handi Respirat Inhaled muscari haler, ory Tract nic Tiotropium Spiriv Agents a Respi mat antagon ist Skeletal Skeletal Muscle muscle Oral Relaxant relaxant Tizanidine Zanafl ex er: Do not swallow capsules , do not shake, inhale deeply and quickly. This is a mainten ance inhaler and should be used routinely, regardle ss of symptom s. Concomitan t therapy with potent CYP1A2 inhibitors (eg, ciprofloxaci n, fluvoxamine ). No boxed warnings Avoid in hepatic and renal imparement, avoid in older adults Do not stop this medicati on abruptly, if you notice liver problem s like darkenin g of the urine, fatique Hepatotoxici ,lack of ty, appetitie hypotension, s, sedation, nausea, withdrawal abdomin syncrome al pain, lightcolored stools, vomiting, or yellowskin contact a healthca re provider, this medicati Analgesi Opioid c (Pain Analges Oral Medicati ics on) Tramadol Ultra m Nasac Triamcinolo ort ne Nasal AQ Intranas Corticost nasal al eroid spray steroid on may affect your blood pressure and heart rate Take BOXED only as WARNINGS: prescrib RIks of ed, this medication medcatio errors n is only Addication, for you abuse, and Hypersensiti and you misuse vity to alone to REMS tramadol, take. program opioids or Keep in Life any a safe threatening Constipation component place respiratory Respiratory of the and out depression depresson formulation of reach Accidental Opioid Use in of ingestion withdrawal pediatric children Ultra-rapid CNS paitents or pets. metabolim of depression less than 12 Avoid tramadol Seizures years old driving Neonatal and Signficant and opioid withdral Serotonin respiratory doing syndrome syndrome dression other Interactions Concomitan tasks or with drugs t use with actions affecting 14 days of that call Cytochrome an MAOI for you P450 to be enzymes alert until Risk from you see concomitant how this use with drug benzodiazepin affects es you. None Cream, Corticost Topical ointment None Triamcinolo Kenal eroid steroid , lotion ne Topical og None Nasal irritation and burning, headache, pharyngitis, Epistaxis, taste perversion None Dry skin, burning sensation, stinging, use proper administr ation techniqu e for this product pruritus/atro phy at site of administratio n Partial Smoking nicotinic Cessatio recepto oral n Aid r agonist Chant Varenicline ix Start medicati on 1 week Nausea/Vo before miting, the quit Constipation precautions: date. , flatulence, hypersensiti Serious Take Sleep vity neuropsychiatr after disturbances ic events, food with (insomnia, seizure, MI a full abnormal glass of dreams) water. No tapering needed. Antiem Antihista etic oral mine Agent Atara x, Hydroxyzin Vistari e l patients should avoid activities requiring mental alertness or coordina tion until drug effects are known, as drug may cause dizzines s or sedative effects Acetamino Tylen phen ol Centrall y acting Analgesi analges c ic Oral Documente d hypersensiti vity or related product including cetirizine None and levocetirizin e and components of the formulation, QT prolongation Sedation, headache, dry mouth, fatigue limit dose from all sources/ routes to Precaution: <4g/day; alcoholism; be hepatic aware of hepatic impairment; combinat disease or limit dose from ion impairment; all products hypersensiti sources/routes Hepatotoxici containin vity to <4g/day ty g acetamin ophen; avoid alcohol use Ibuprofen Oral BW: may increase risk of ASCVD events; increase risk of GI events/bleedin g. Precaution: caution in older adults due to GI bleeds; caution in hypertension, fluid retention, NSAID and HF; allergy or increase risk hypersensiti of renal injury; vity; CABG avoid in surgery pregnancy edema; increased BP; abdominal discomfort; heartburn Oral asthma, Precaution: rhinitis, and avoid chronic nasal use increased report BP; unusual dyspepsia/G bleeding; Aleve, Napro syn Analgesi c NSAID Aspirin edema; increased BP; abdominal discomfort; heartburn Advil, Motrin Analgesi c NSAID Naproxen Oral BW: may increase risk of ASCVD events; increase risk of GI events/bleedin g. Precaution: caution in older adults due to GI bleeds; caution in hypertension, fluid retention, NSAID and HF; allergy or increase risk hypersensiti of renal injury; vity; CABG avoid in surgery pregnancy Bayer Analgesi NSAID , c and Take with food to avoid GI irritation; do not drink alcohol or smoke while taking; MDD OTC is 1200mg injection techniqu e if administ ered subcutan eously; risks of DVT, MI, and stroke are associat ed with use of ESAs; monitor blood pressure due to the risk of uncontro lled hyperten sion; Ecotri n antiplat elet polyps syndrome Delsy Dextrometh m, orphan Robit ussin NMDA recepto r Antitussi antagon ve ist Oral Diphenhydr Bena amine dryl Antiallergy First Generat ion Antihist Oral; amine Topical Guaifenesi Mucin n ex Expector ant Oral >325mg/day in elderly; GI bleed; increase bleeding risk; avoid in severe liver disease; avoid if GFR <10; avoid in pregnancy I ulcer, confusion, Reye's syndrome, dizziness Take with full glass of water; avoid combinat ion products containin g aspirin avoid activities requiring mental alertness ; use sugarfree Precautions: formulati do not use in ons for children <2 diabetes MAOI use years; caution patients; concurrently in cough with if liquid or within 14 excessive fatigue; shake days secretions dizziness well avoid alcohol; avoid with medicati Precautions: ons avoid in causing elderly due to drowsine strong ss; avoid anticholinergic topical effects; on caution in dizziness; chickenp glaucoma; drowsiness; ox, newborns/pr caution in dyskinesia; measles, emature BPH; anticholinerg blisters, infants; excitation may ic side large nursing occur in effects; areas of mothers children xerostomia skin Take with full Precautions: glass of avoid in water; children <2 use years; caution sugarin cough with free excessive nausea; formulati none secretions vomiting ons for diabetes patients Pseudoeph Sudaf edrine ed Alpha Recept Deconge or stant Agonist Oral Antiallergy Intranas al Cortico Intranas steroid al Precautions: immunosuppr ession with prolonged use; nasal effects (nasal alteration, nasal erosion, epistaxis) Antiallergy Second Generat ion Antihist amine Oral none Precautions: Caution in hepatic and renal impairement none Precautions: Caution in renal impairement; do not administer at the same time with aluminum or magnesium antacids or with fruit juices Fluticasone Flona Nasal se Loratadine Clariti n Fexofenadi Allegr ne a Antiallergy Cetirizine Precautions: Caution in CAD; hypertension, hypertensio glaucoma, n; MAOI hyperthyroidis use m, ischemic concurrently heart disease, or within 14 BPH, days arrhythmias Second Generat ion Antihist amine Oral Zyrtec Antiallergy Second Generat ion Antihist amine Oral none Precautions: Caution in hepatic and renal impairement, older patients may be more senstiive to side effects hypertensio n; tachyarrhyth mia; insomnia; anxiety; myocardial infarction avoid taking at or near bedtime to avoid insomnia advise patients on the Headache, proper nasal administr irritation and ation burning, techniqu epistaxis, e for this glaucoma product Patient should avoid activities requiring mental alertness until drug effects are Headache realized Headache, sedation, dry mouth, nausea, insomnia take the suspensi on with water only (not fruit juices), shake well before use drowsiness patients should avoid activities requiring mental alertness or coordina tion until drug effects are known, as drug may cause dizzines s or sedative effects Blow your nose before use; Do not tilt Oxymetazo your Afrin line head back Precautions: before CI: do not local nasal dry nose, using Adrener use for effects; sneezing, this Deconge gic Intranas more than 3 rebound nasal nasal medicati stant Agonist al days congestion irritation on All formulati ons: Begin on Patch: quit date dermatologi Derm: c side apply to effects a clean, (erythema, dry pruitus, hairless Precaution: burning), area (on Ideally, stop sleep the back, Nicod smoking while disturbances chest or erm using but pt arms), CQ, may lapse and Gum and rotate Nicotine Habitr continue to Lozenge: site of ol, use. Mouth/throat applicati Nicor Active PUD, irritation, on, taper ette <2 weeks hiccups, GI use since MI, (dyspepsia, serious nausea) and Gum arrhythmias or lightheaded and angina, ness Lozenge pregnancy/bre especially if : rotate Nicotini astfeeding not used sites in c Legally, can't correctly mouth, Choline sell to Gum only: use a rgic Lozenge someone jaw muscle min of 9 Smoking Recept MINT - soy <21yo aches, may pieces in Cessatio or Buccal; allergy/hype stick to the 1st 6 n Aid Agonist Topical rsensitivity Gum: TMJ dental work weeks, Avoid food/bev erages for 15min before and during the use of NRT, taper use Pyridi Phenazopy um, ridine AZO Urinary Analgesi Analges c ic Oral Red to orange color Precaution: of urine and caution in feces and glucose-6staining of phosphate contacts and dehydrogenas clothing; e (G6PD) headache; deficiency hemolytic may lead to anemia; renal hemolytic methemoglo insufficiency anemia binemia Gum only: use the slow chew, park, repeat method, max of 24 pieces/d ay Lozenge only: Max of 20 pieces/d ay may discolor urine and feces to red or orange, which is normal and not harmful, and may stain clothing and contact lenses; take drug with or after food and with full glass of water; medicati on will not cure a urinary infection Polyethylen Mirala e glycol x 3350 Docusate Bisacodyl Sennosides Precaution: prolonged/freq uent/excessiv e use may lead to electrolyte imbalance Hypero smotic Laxativ Laxative e Oral Known or suspected bowel obstruction Emollie nt Laxativ Laxative e Oral Concomitan t use of mineral oil; intestinal obstruction; acute abdominal pain, nausea, or vomiting None Stimula nt Laxativ Laxative e Oral Appendicitis ; intestinal obstruction; gastroenteri tis None Stimula Laxative nt Oral None Colac e Dulcol ax Senn a None Diarrhea; flatulence; nausea; stomach cramps; swollen abdomen Abnormal taste in mouth; diarrhea; stomach cramps; hepatotoxicit y mix thorough ly with liquid to ensure powder is complete ly dissolve d and drink right away; may take up to ~4 days for results may take up to 3-5 days for results Swallow tablets whole do not crush/br eak/che w; do not take within 1 hour of antacids, milk, or milk products ; may take up Stomach to 24 cramps; hours for diarrhea results Abnormal do not electrolytes; take stomach other Laxativ e cramps; diarrhea Methylcellul Citruc ose el Psyllium BulkFormin g Laxativ Laxative e Oral None BulkFormin g Laxativ Laxative e Oral None Meta mucil drugs within 2 hours; take at bedtime if taking once per day; do not chew/bre ak/crush tablet Mix powder with full glass of cold water or milk and stir well before Precaution: drinking; caution in take phenylketonuri Stomach tablet a - some cramps; with full products have diarrhea; glass of phenylalanine flatulence water Separate from other drugs by 2 hours; if you do not take this drug with lots of liquid (at least 8 oz), it may swell and block your Precaution: throat or avoid in esophag patients that Stomach us and have difficulty cramps; may swallowing; diarrhea; cause caution in flatulence; choking; phenylketonuri borborygmu do not a - some s (stomach chew/bre products have growling/ru ak/crush phenylalanine mbling) capsule Lotrim in AF, Micati Miconazole n, Monis tat Antifung Imidazo Topical; al le Vaginal None Meclizine Antive rt Motion Sickness / Vertigo Aid/Antinausea Histami ne-1 Recept or Antago nist Oral Antinausea Histami ne-1 Recept or Antago nist Oral Dimenhydri Dram nate amine none burning; irritation; pruritis Precaution: use cautiously in patients with BPH, asthma, and glaucoma given anticholinergic effects. use cautiously in the elderly (65 years of age and older) due to these effects and sedation Sedation Precaution: use cautiously in patients with BPH, asthma, and glaucoma given Sedation Vaginal: do not have vaginal sex while using this drug condoms or diaphrag ms may not work while using and for a period of time after you stop using. Vaginal and topical: wash hands before and after use avoid alcoholic beverag es and other CNS depress ants while taking this drug, take with food to decreas e GI symptom s avoid alcoholic beverag es and other CNS depress anticholinergic effects. use cautiously in the elderly (65 years of age and older) due to these effects and sedation ants while taking this drug AntiSalicyla diarrheal te Oral hypersensiti vity to salicylates, ulcer/bleedi ng problems, children <12 years of age, children and teens recovering from chicken-pox or flu-like symptoms, breastfeedin g, pregnant None Fecal discoloration , tongue discoloration , tinnitus GI Opioid Recept Antior diarrheal Agonist Oral bloody/blac k stools, febrile, invasive gut bacterial infections and antibioticassociated diarrhea (C. difficile) Constipation , abdominal pain, dizziness Pepto Bismuth Subsalicyla Bismo te l Loperamid Imodi e um BW: Torsades, cardiac arrest, and death due to high doses Report if there are signs of an allergic reaction or if ringing in the ears, hearing loss, or any other changes in hearing occur; may cause a temporar y, harmless darkenin g of the tongue and/or stool. Avoid driving and doing other tasks or actions that call for you to be alert as well as the use of alcohol, marijuan a or other forms of cannabis , or sedating prescripti on or OTC drugs due to possible sedative effects Docosanol Abrev a Antiviral Antiviral Topical Carbamide Debro Peroxide x Antiinflamma Cerume tory nolytic Otic None apply at first sign of a cold sore, wash hands before Acne, and after application use, use Precaution: for site reaction, no more use on pruritis, dry than 10 lips/face only skin days Recent ear surgery or tubes, ear drainage/dis charge/pain, eardrum perforation, Precaution: age <3 avoid contact years with eyes Patad Olopatadin ay, e Patan ol Antiallergy Histami ne-1 Recept or Antago Ophthal nist mic None Precaution: avoid in children <2 years instruct on proper administr ation of ear drops, keep drops in ear Redness, several irritation minutes wash hands before administr ation, instruct on proper administr ation of eyedrop s, twicedaily dosing should Headache, be at burning least 6-8 sensation in hours eyes apart, remove contact lens prior to administr ation and wait at least 10 min before reinserti ng Hydrocortis Cortis one Topical one Adapalene Antiinflamma Cortico tory steroid Topical None Antiacne None Differi n Retinoi d Topical Dry skin, burning Precaution: sensation/pr Avoid in uritis/stingin infected, open, g at site of or cracked administratio lesion n, headache redness, Precaution: scaling, Avoid contact dryness, w/ eyes, lips, itching, mouth, nose burning scrapes, cuts, improves apply thin layer to affected area of skin, skin should be clean and intact at site of applicati on, avoid contact with eyes and do not ingest by mouth, avoid occlusiv e dressing s or tightfitting clothes over site of administr ation, wash hands after applicati on do not apply on cuts, abrasion s, eczemat photosensitivit after 1st y month Lactase Niacin Lactai d AntiLactose Intoleran ce Enzyme Oral None Antihype rlipidemi c Vitamin Oral Precaution: Increased bleeding risk, Active liver fasting blood disease, sugars, uric PUD, acid levels. arterial Unstable hemorrhage angina None Niasp an, Niaco r ous, or sunburn ed skin; apply thin layer to affected, intact skin once daily at bedtime, apply sunscree n spf>15 take with foods to prevent intestinal gas from forming, take at first bite of dairyor lactosecontainin None g food. start with a low dose and titrate based on tolerabilit y (primaril y flushing), avoid alcohol and warm beverag es with niacin to reduce flushing, Flushing, aspirin headache, or hepatotoxicit NSAID y, gout, 30 min hyperglycem prior to ia niacin or Terbinafine Lamis il Allylami ne Antifung Derivati al ve Topical None None take at bedtime with a low-fat snack to help reduce flushing Apply the antifung al to the clean, dry affected area as directed (in the morning or evening if once daily, or both times if twice daily). Massage the medicati on into the area. Note that creams and solutions are easier to work into the skin. Avoid getting the product in your eyes. Wash hands thorough ly with soap irritation, and burning, water itching/dryne before ss and after applying the product. Nasac Triamcinolo ort, ne Kenal og AntiTopical/i inflamma Cortico ntranasa tory steroid l None Lidocaine Asper creme , Beng ay Analgesi c/ Anesthet Anesth ic etic Topical Salicylic Acid Comp ound W, Stride x Antiacne Keratol ytic Agent Topical None None Precaution: Increased risk of systemic absorption associated with irritated or broken skin, application of external heat sources, a covered application site, and large doses or large treatment areas hypersensiti vity to aspirin, Children/tee ns – recovering from chickenpox/ flu – r/o Reye syndrome None Nasal irritation and burning, headache, pharyngitis, Epistaxis, taste perversion, glaucoma, pneumonia, secondary hypocortisoli sm, osteoporosis Application site reactions (eg, blisters, bruising, burning sensation, etc) have been reported; interruption of treatment may be necessary Advise patients on the proper administr ation techniqu e for this product Instruct patient to avoid applying to nonintact skin face: Apply gel to affected area use sunscree n spf ≥ 15, warts: Wash hands skin irritation before and and after potential use. systemic Before toxicity, sun treatmen sensitivity t, soak (use the sunscreen affected spf ≥ 15), area in peeling warm water for 5 minutes. Wash and dry the affected area thorough ly before applicati on Benzoyl Peroxide Benze PrO, PanO xyl, Riax, Zapzy t Antiacne Calcium Carbonate Tums, AlkaSeltze r, Maalo x Antacid Peroxid e Topical Antacid Oral None None Hypercalce mia none Bleaching, photosensiti vity, dermatologi c side effects (peeling, drying of skin, erythema, scaling, itching, swelling) constipation, Flatulence, Swollen abdomen, nephrolithias is Apply thin layer to affected, intact skin once daily at bedtime Protect affected areas from sun exposur e (sunscre en spf>15), Avoid contact w/eyes, lips, mouth, nose, cuts/scra pes, clothes/h air – bleachin g, New users: use sparingly , start low and go slow Heartbur n: longer duration of action when taken after Ketoconaz Nizor ole al Antifung Imidazo al le Topical None None Burning sensation, Pruritus meals, drink water, stay active to avoid constipat ion Apply the antifung al to the clean, dry affected area as directed (in the morning or evening if once daily, or both times if twice daily). Massage the medicati on into the area. Note that creams and solutions are easier to work into the skin. Avoid getting the product in your eyes. Wash hands thorough ly with soap and water before and after Lotrim Clotrimazol in, e Micotr in Antifung Imidazo al le Topical None None Burning sensation, Pruritus, blistering, edema, erythema applying the product. Topical gel/foam : Advise patient to avoid fire, flame, and smoking during and after applicati on since products are flammabl e Advise patients using the intravagi nal formulati on to not use tampons during treatmen t. Instruct patients using the topical formulati on to not use occlusiv e dressing s over the treated area. Patient should avoid douches or other intravagi nal products during drug therapy.