Future of Genetics Student Slides F24 PDF
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These student slides cover various aspects of genetics, including genome editing, epigenetics, and personalized medicine. They discuss topics such as CRISPR, methylation, and histone modification.
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THE FUTURE OF GENETICS Genome Editing Epigenetics Personalized Medicine (Pharmacogenomic Testing) Genetic Testing for disease prediction CRISPR (CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS) EPIGENETICS Epigenetics Changes in gene...
THE FUTURE OF GENETICS Genome Editing Epigenetics Personalized Medicine (Pharmacogenomic Testing) Genetic Testing for disease prediction CRISPR (CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS) EPIGENETICS Epigenetics Changes in gene expression because of DNA modification (not a change in the DNA sequence) Genome The complete set of DNA of an organism Epigenome Chemical modifications that mark genes & tell them when they should be active EPIGENETICS Methylation Adding a small molecule to DNA stops the genes being read and ‘turns off’ it off EPIGENETICS Histone Modification DNA is wrapped around proteins called histones DNA tightly wrapped on histones…gene inaccessible & “off” DNA loosely wrapped on histones…gene accessible & “on” INHERITANCE OF THE EPIGENOME?? Epigenetic change passed from one cell to next during mitosis In contrast most of the epigenome is reset during meiosis…but not all Transgenerational epigenetics?? PERSONALIZED MEDICINE (PHARMACOGENOMIC TESTING) PHARMACOGENOMIC TESTING PHARMACOGENOMIC TESTING