Fall 2024 FDSC-626 Food Safety Risk Assessment PDF

11/11/2024 UNIT 7 ACTIVITIES FDSC-626 11 1 https://www.nbcnews.com/ www.theguardian.com/...

11/11/2024 UNIT 7 ACTIVITIES FDSC-626 11 1 https://www.nbcnews.com/ www.theguardian.com/ 2 2 1  11/11/2024 https://www.lawsuit-information-center.com/ 3 3 4 4 2  11/11/2024 5 5 6 6 3  11/11/2024 7 7 www.cbc.ca 8 8 4  11/11/2024 9 9 10 10 5  11/11/2024 11 11 12 12 6  11/11/2024 https://www.who.int/ 13 13 Microbiological Risk Assessment UNIT 7 FDSC-626 14 14 7  11/11/2024 15 15 16 16 8  11/11/2024 Case study. Salmonella in eggs. 17 Case study https://www.usatoday.com/ 18 9  11/11/2024 Case study www.poultryworld.net/ 19 Case study https://ecdc.europa.eu 20 10  11/11/2024 Case study https://ecdc.europa.eu 21 22 22 11  11/11/2024 Case study Describe the characteristics of the pathogen agent: Salmonella enterica spp. - Facultative anaerobic bacterium - Prevalence: “Over 2 000 serotypes of Salmonella have been identified, the most prevalent of which are S. Enteritidis, S. Typhimurium and S. Heidelberg.” - Differences among serovars in terms of occurrence, virulence and pathogenicity for humans - Growth temperature range of 5.2–46.2°C - pH levels between 3.8–9.5 -… Widely distributed in environment (soil, vegetation, sewage) 23 24 12  11/11/2024 1- MRA / Hazard Identification Describe the toxic effects/illness: Infection or intoxication? toxins produced? Clinical forms Duration of illness Severity (morbidity, mortality, sequelae) Physiopathology Secondary transmission Transport of pathogen through the gastrointestinal tract Susceptible populations Virulence factors … 25 Case study “Salmonellosis is characterized by diarrhoea, fever, abdominal pain or cramps, vomiting, headache and nausea. The incubation period ranges from 8 to 72 hours. Symptoms can last up to a week. Salmonella infections vary from mild to severe, and are occasionally fatal. Fatalities are more often seen in susceptible populations, which include infants, the elderly and the immuno-compromised. In the United States of America between 1985 and 1991, there were 54 reported S. Enteritidis outbreaks occurring in hospitals or nursing homes, accounting for 90% of all Salmonella-associated deaths, but only 12% of all cases. A small proportion of infected individuals may develop Reiter’s syndrome, an arthritic disease characterized by symptoms of joint pain, eye irritation and painful urination” 26 13  11/11/2024 Case study Describe which food products and/or modes of production are associated to exposure § on Poultry, page 4 “Poultry have a major role […] the pathogen during slaughter and processing.” § on Eggs, page 4 “Salmonella is transmitted to eggs by two routes[…] reduced by cleaning and disinfection of the environment..” 27 Case study Identify the dose-response relationship, and which model was applied to fit epidemiological data. 28 14  11/11/2024 Case study 29 30 30 15  11/11/2024 31 Case study Assuming a 20% prevalence of contaminated broilers, the estimated frequency and cumulative distribution of average risk per serving are shown in Figure 8. The expected risk per serving is 1.13E-5, or 1.13 illnesses per 100 000 servings. This value represents the average risk for all individuals in the population that consume servings of chicken that are stored, transported and prepared in the manner described in the model, and also accounts for the probabilities that the serving was from a chicken contaminated with Salmonella, and that the meal was undercooked. 32 16  11/11/2024 Case study 33 Conclusions about MRA Overall methodology comparable to the food safety risk assessment of chemical contaminants. Specificities: - Growth of microorganisms - Transmission - Virulence - Survival of the spores/toxins during processing - Concentrations over several logs - (More?) complex predictive models 34 17