Antidysrhythmic Homework 2024 PDF - Cordie Payton

Cordie Payton; StudentID: 1298244 Strengths and Improvement Opportunities Antidysrhythmic Homework 2024 Course: Drug Action II ‡Instructor: Kuhl ‡Questions: 20...

Cordie Payton; StudentID: 1298244 Strengths and Improvement Opportunities Antidysrhythmic Homework 2024 Course: Drug Action II ‡Instructor: Kuhl ‡Questions: 20 95.45% My Score QUESTION CORRECT INCORRECT PARTIAL CREDIT For each of the following, Fill in the letter of the appropriate antiarrhythmic agent that matches each BBW. You may reuse answers. 1 (2 points total) Hepatotoxicity__1__ a. Dofetilide Symptomatic or Class IV heart failure__2__ b. Procainamide Start or restart only in the hospital__3__ c. Amiodarone Pulmonary fibrosis/pneumonitis__4__ d. Quinidine Bone marrow suppression in 1st 12 weeks__5__ e. Dronedarone Answer 1: C Answer 2: E Answer 3: A Answer 4: C Answer 5: B For each of the following Antiarrhythmic classes, fill in the letter that matches its primary mechanism of action. You may reuse 2 answers. (2 points) Class 1 __1__ a. Magnesium channel blockade Class 2 __2__ b. Calcium channel blockade Class 3 __3__ c. Sodium channel blockade Class 4 __4__ d. Potassium channel blockade e. Beta-adrenergic receptor blockade Answer 1: C Answer 2: E Answer 3: D Answer 4: B Which one of the following antiarrhythmic agents will have no effect (or slightly decrease) on the ERP? 3 X A: Diltiazem > B: Lidocaine X C: Disopyramide X D: Defetilide X E: Adenosine Which of the following are TRUE regarding adenosine? (Select THREE That Apply) 4 > A: MOA impacts several phases of the action potential > B: Extremely short half-life and DOA > C: Used primarily for supraventricular tachycardia X D: Class IV antiarrhythmic X E: Metabolized via plasma hydrolysis X F: Side effects include hypertension and thrombocytopenia Blockade of which one of the following is most likely to result in QTc prolongation and Torsades de Pointes? 5 X A: Beta adrenergic receptor X B: Sodium channel > C: Potassium channel X D: Calcium channel X E: Magnesium channel  A patient is started on an antiarrhythmic and complains of N/V/D. Which agent is most likely to cause this? 6 X A: Disopyramide X B: Flecainide X C: Propafenone X D: Dofetilide > E: Quinidine Which agents will ONLY be used IV to acutely control dysrhythmias?(Select All That Apply) 7 > A: Adenosine X B: Sotalol > C: Ibutilide X D: Dofetilide > E: Lidocaine A class III drug would have its primary effect on: 8 X A: Phase 0 X B: Phase 2 > C: Phase 3 X D: Phase 4 X E: Class III drugs do not cause notable changes in the action potential All of the following agenst should be given cautiously in a patient with receiving amiodarone EXCEPT? 9 X A: Warfarin X B: Theophylline X C: Simvastatin X D: Levothyroxine > E: Dipyridamole A patient initiated on rate control for atrial fibrillation develops peripheral edema. Which one of the following agents is most 10 commonly associated with this side effect? > A: Diltiazem X B: Amiodarone X C: Quinidine X D: Mexiletine X E: Dofetilide A diabetic patient notices that she no longer has her typical symptoms when her blood glucose decreases. What antiarrhythmic is 11 most likely to be responsible? X A: Propafenone X B: Procainamide X C: Quinidine X D: Dofetilide > E: Sotalol Which one of the following antiarrhythmic agents will have its primary effect on Phase 0 of the action potential? 12 X A: Diltiazem X B: Dofetilide > C: Flecainide X D: Amiodarone X E: Adenosine Which of the following agents have Class I IV (all classes) effects? (Select TWO That Apply) 13 > A: Amiodarone X B: Propafenone > C: Dronedarone X D: Disopyramide X E: Procainamide  An ICU patient is started on lidocaine for recurrent PVCs. What drug class is lidocaine? 14 X A: Class IA > B: Class IB X C: Class IC X D: Class III X E: It is classified as a miscellaneous antiarrhythmic A 65 year old male patient with prostatic hypertrophy is started on an antiarrhythmic and is now having trouble with urinary 15 retention. He also says his mouth is dry all the time. Which agent is most likely the cause? X A: Amiodarone X B: Mexilitene X C: Flecainide > D: Disopyramide X E: Propafenone Which one of the following antiarrhythmic agents will have its primary effect at the AV node? 16 > A: Diltiazem X B: Dofetilide X C: Flecainide X D: Disopyramide X E: Mexiletene Which one of the following explains why long-term management with ANY antiarrhythmic agent is generally avoided unless the 17 rhythm can not be controlled by other interventions? X A: Limited efficacy of the agents X B: Increased risk of Torsades seen with these agents when used chronically > C: Increased mortality has been see when these are agents are used chronically. X D: Increased risk of heart failure is seen with these agents when used chronically X E: Increased risk of SLE is seen when these agents are used chronically A asthmatic patient with very poor control (daily use of SABA) is to be started on antidysrhythmic therapy. Based upon their MOA, 18 which one of the following would be the LEAST likely to worsen the patients symptoms? X A: Amiodarone X B: Sotalol X C: Propafenone X D: Esmolol > E: Disopyramide What is the main mechanism by which digoxin exerts its antidysrhythmic action? 19 X A: Decreased intracellular calcium > B: Decreased sympathetic tone / Increased parasympathetic tone X C: Blockade of calcium channels X D: Blockade of sodium channels X E: Adjust and stabilize resting membrane potential While many agents must be used cautiously in patients with heart failure, which antiarrhythmic agent should be avoided in patients 20 with symptomatic heart failure? X A: Procainamide X B: Mexiletine X C: Dofetilide X D: Metoprolol > E: Dronedarone ©2024 ExamSoft Worldwide LLC. All Rights Reserved.