Ethnopharmacological research.pdf

Department of Pharmacognosy and Herbal Medicine, SOPPS, UDS. Ethnopharmacology (Ethnopharmacological research ) Pharm D. 300. 2nd trim' 2024.  Demonstrate an understanding of the principles and practices utilized in ethnopharmacological research....

Department of Pharmacognosy and Herbal Medicine, SOPPS, UDS. Ethnopharmacology (Ethnopharmacological research ) Pharm D. 300. 2nd trim' 2024.  Demonstrate an understanding of the principles and practices utilized in ethnopharmacological research.  Research tools in ethnopharmacology  Online resources in ethnopharmacological research Pharm D. 300. 2nd trim' 2024.  Ethnopharmacological research involves the scientific study of traditional medicines and their biologically active compounds  It involves the study of how indigenous use various substances from nature to treat diseases and maintain their health.  Ethnopharmacological research is vital in the quest to search for new drugs Pharm D. 300. 2nd trim' 2024. 3  Identify and document traditional medicinal knowledge  This is achieved through ethno-survey to; 1. gather information about the plants 2. traditional methods of preparation 3. administration, and dosage. Pharm D. 300. 2nd trim' 2024. 4  Identify and document traditional medicinal knowledge Pharm D. 300. 2nd trim' 2024. 5  Investigate the efficacy and safety of traditional remedies  This is when the gathered or document plants are screen for their biological activity through various scientific methods.  Biological activity may include: wound healing property, anti-malaria activity, anti-septic property, anti-,microbial activity, etc.  The safety profile of the plants can be assess as well. Pharm D. 300. 2nd trim' 2024. 6  Investigate the efficacy and safety of traditional remedies Pharm D. 300. 2nd trim' 2024. 7  Discover new bioactive compounds  Involves the isolation and characterization of bioactive compounds from traditional remedies.  These compounds can be further studied for their therapeutic potential (through biological assays). Pharm D. 300. 2nd trim' 2024. 8  Discover new bioactive compounds Pharm D. 300. 2nd trim' 2024. 9  Promote cultural preservation and sustainable resource management  Emphasizes the importance of preserving indigenous knowledge systems and the sustainable use of natural resources. Pharm D. 300. 2nd trim' 2024. 10  Identification of Novel Drug Candidates  Led to the discovery of important drugs such as quinine, artemisinin, and taxol, which have revolutionized the treatment of malaria, cancer, and other diseases. Pharm D. 300. 2nd trim' 2024. 11  Identification of Novel Drug Candidates First ever scientific report on this plant hence can be considered as a new drug candidate Pharm D. 300. 2nd trim' 2024. 11  Research tools in ethnopharmacology involve a multidisciplinary approach that combines field, laboratory, and library/herbarium methods. Pharm D. 300. 2nd trim' 2024. 12  Ethnobotanical Surveying and Fieldwork: This involves conducting surveys and fieldwork to gather information about the traditional use of plants and other natural materials by local communities. This includes documenting the plants used, their preparation methods, and the diseases they are used to treat. Pharm D. 300. 2nd trim' 2024. 13  Laboratory Methods 1.Pharmacological Assessment: The pharmacological activity of the plants is assessed in laboratory settings using various targets. This includes testing for bioactivity, toxicity, and efficacy. 2.Pharmacokinetic Evaluations: Laboratory studies evaluate the pharmacokinetic properties of the plants, such as their absorption, distribution, metabolism, and excretion (ADME) profiles Pharm D. 300. 2nd trim' 2024. 14  Library and Herbarium Methods 1. Literature Evaluations: Researchers review existing literature on the plants and their traditional uses to identify gaps in knowledge and potential leads for further study. 2. Herbarium Analysis: Herbarium collections are used to identify and verify the plant species used in traditional medicine. This helps in understanding the chemical composition and potential bioactive compounds. Pharm D. 300. 2nd trim' 2024. 15  Additional Tools 1. Statistical Analysis: Statistical tools are used to analyze and interpret the data collected from field and laboratory studies. This includes methods such as regression analysis, ANOVA, and cluster analysis. 2.Bioinformatics: Bioinformatics tools are used to explore and elucidate the mechanisms of action of the bioactive compounds found in the plants. This involves the use of computational methods such as network analysis and docking studies. Pharm D. 300. 2nd trim' 2024. 16  Online resources play a crucial role in ethnopharmacological research, providing access to a wealth of information and literature in this interdisciplinary field. Pharm D. 300. 2nd trim' 2024. 17  Journal of Ethnopharmacology on ScienceDirect  Research gate  ResearchGate : ResearchGate hosts a publication on statistical tools in ethnopharmacology  Pubmed  Google scholar  etc Pharm D. 300. 2nd trim' 2024. 18 21