Drugs That Inhibit Bacterial And Viral Replication PDF

**Drugs that Inhibit/Disrupt Bacterial Cell Wall ** - Medications like penicillins and cephalosporins inhibit bacterial cell wall synthesis or activate enzymes that interfere with the cell wall, contributing to weakening and bacterial cell death through lysis.  **Drugs that Increase...

**Drugs that Inhibit/Disrupt Bacterial Cell Wall ** - Medications like penicillins and cephalosporins inhibit bacterial cell wall synthesis or activate enzymes that interfere with the cell wall, contributing to weakening and bacterial cell death through lysis.  **Drugs that Increase Cell Membrane Permeability ** - Agents such as amphotericin B make the cell membrane more permeable, resulting in the loss of essential intracellular components.  **Drugs that Cause Lethal Inhibition of Bacterial Protein Synthesis ** - Aminoglycosides (e.g., gentamicin) fatally inhibit the process of bacterial protein production to contribute to cell death.  **Drugs that Cause Nonlethal Inhibition of Protein Synthesis ** - Drugs like tetracyclines hinder the synthesis of bacterial proteins but do not kill the bacteria outright; they merely impede bacterial proliferation.  **Drugs that Inhibit/Disrupt Bacterial Synthesis of DNA and RNA ** - Medications like rifampin, metronidazole, and fluoroquinolones (e.g., ciprofloxacin) prevent the production of DNA and RNA in bacteria or interfere with the operation of these nucleic acids, inhibiting bacterial replication.   **Antimetabolites ** - Medications like trimethoprim and sulfonamides interfere with specific bacterial metabolic processes, reducing or creating dysfunctional metabolic products and effectively hindering bacterial growth.  **Drugs that Suppress Viral Replication ** - Many drugs inhibit viral replication by targeting enzymes essential for viral replication, such as DNA polymerase, reverse transcriptase, protease, integrase, and neuraminidase.