Drug List Classification PDF

Summary

This document provides a list of drugs, their mechanisms of action, and their effects on the adrenergic and cholinergic systems. It's useful for medical professionals and students learning about pharmacology.

Full Transcript

Drug-list Drug Name Mechanism of Action Direct/Indirect Adrenergic/Cholinergic Acebutolol Selective beta-1 blocker, used for Direct Adrenergic Antagonist hypertension and arrhythmias Albuterol Selecti...

Drug-list Drug Name Mechanism of Action Direct/Indirect Adrenergic/Cholinergic Acebutolol Selective beta-1 blocker, used for Direct Adrenergic Antagonist hypertension and arrhythmias Albuterol Selective beta-2 adrenergic agonist, causes Direct Adrenergic Agonist bronchodilation Atenolol Selective beta-1 blocker, used for Direct Adrenergic Antagonist hypertension and heart disease Atropine Blocks muscarinic receptors, reducing Direct Cholinergic Antagonist parasympathetic activity Benztropine Blocks muscarinic receptors, used in Direct Cholinergic Antagonist Parkinson's disease Bethanechol Stimulates muscarinic receptors, used for Direct Cholinergic Agonist bladder and bowel atony Botulinum toxins Inhibits acetylcholine release from nerve Indirect Cholinergic Antagonist terminals Carbachol Stimulates muscarinic receptors, used in Direct Cholinergic Agonist glaucoma Carvedilol Non-selective beta and alpha-1 blocker, used Indirect Adrenergic Antagonist for heart failure Clonidine Alpha-2 adrenergic agonist, inhibits Direct Adrenergic Agonist sympathetic outflow, lowers blood pressure Cocaine Inhibits norepinephrine reuptake, increasing Indirect Adrenergic Agonist synaptic levels Curare Non-depolarizing neuromuscular blocker, Direct Cholinergic Antagonist inhibits nicotinic receptors (Nicotinic) Cyclopentolate Blocks muscarinic receptors, used for eye Direct Cholinergic Antagonist dilation Donepezil Inhibits acetylcholinesterase, increasing Indirect Cholinergic Agonist acetylcholine levels in the brain Dopamine Activates alpha and beta adrenergic Direct Adrenergic Agonist receptors, stimulates dopamine receptor Dutasteride Inhibits 5-alpha reductase, used for benign Indirect Adrenergic Antagonist prostatic hyperplasia Echothiophate Irreversible inhibitor of acetylcholinesterase, Indirect Cholinergic Agonist (Long- used in glaucoma acting) Edrophonium Reversible inhibitor of acetylcholinesterase, Indirect Cholinergic Agonist used to diagnose myasthenia gravis Esomolol Short-acting selective beta-1 blocker, used Direct Adrenergic Antagonist for acute tachycardia Finasteride Inhibits 5-alpha reductase, used for benign Indirect Adrenergic Antagonist prostatic hyperplasia Flumazenil Competitive antagonist at benzodiazepine Direct Cholinergic Antagonist receptors, used in overdose treatment Guanethidine Inhibits norepinephrine release by disrupting Indirect Adrenergic Antagonist vesicle fusion Hemicholinium Inhibits choline uptake, decreasing Indirect Cholinergic Antagonist acetylcholine synthesis Ipratropium Blocks muscarinic receptors, used for COPD Direct Cholinergic Antagonist and asthma Isoproterenol Stimulates beta-adrenergic receptors (non- Direct Adrenergic Agonist selective) Labetalol Non-selective beta and alpha-1 blocker, used Direct Adrenergic Antagonist for hypertension Mecamylamine Blocks nicotinic receptors in autonomic Direct Cholinergic Antagonist ganglia (Nicotinic) Methacholine Stimulates muscarinic receptors, used for Direct Cholinergic Agonist bronchial hyperreactivity test Metoprolol Selective beta-1 blocker, used for Direct Adrenergic Antagonist hypertension and heart failure Metyrosine Inhibits tyrosine hydroxylase, reducing Indirect Adrenergic Antagonist catecholamine synthesis Neostigmine Inhibits acetylcholinesterase, increasing Indirect Cholinergic Agonist acetylcholine levels Nicotine Stimulates nicotinic receptors Direct Cholinergic Agonist Nicotinic Stimulate nicotinic receptors, increasing Direct Cholinergic Agonist Agonists muscle contraction (Nicotinic) Nicotinic Block nicotinic receptors, causing muscle Direct Cholinergic Antagonist Antagonists relaxation (Nicotinic) Pancuronium Non-depolarizing neuromuscular blocker, Direct Cholinergic Antagonist inhibits nicotinic receptors (Nicotinic) Pilocarpine Stimulates muscarinic receptors, enhancing Direct Cholinergic Agonist parasympathetic activity Pindolol Non-selective beta blocker with intrinsic Direct Adrenergic Antagonist sympathomimetic activity Pirenzepine Blocks muscarinic receptors, reduces gastric Direct Cholinergic Antagonist acid secretion Pralidoxime Reactivates acetylcholinesterase inhibited by Indirect Cholinergic Agonist (Oxime) organophosphates Propranolol Blocks beta-adrenergic receptors (non- Direct Adrenergic Antagonist selective), reduces heart rate and output Reserpine Inhibits vesicular monoamine transporter Indirect Adrenergic Antagonist (VMAT), depleting catecholamines Rocuronium Non-depolarizing neuromuscular blocker, Direct Cholinergic Antagonist used for muscle relaxation (Nicotinic) Scopolamine Blocks muscarinic receptors, used for Direct Cholinergic Antagonist motion sickness Succinylcholine Depolarizes neuromuscular junction, causing Direct Cholinergic Agonist paralysis (Nicotinic) Timolol Non-selective beta blocker, used in Direct Adrenergic Antagonist glaucoma Tiotropium Blocks muscarinic receptors, used in chronic Direct Cholinergic Antagonist obstructive pulmonary disease (COPD) Trimethaphan Blocks nicotinic receptors in autonomic Direct Cholinergic Antagonist ganglia (Nicotinic) Tropicamide Blocks muscarinic receptors, used for eye Direct Cholinergic Antagonist dilation Varenicline Partial agonist at nicotinic receptors, used in Direct Cholinergic Agonist smoking cessation (Partial) Vesamicol Inhibits acetylcholine storage in vesicles Indirect Cholinergic Antagonist Zileuton Inhibits lipoxygenase, reducing leukotriene Direct Adrenergic Antagonist synthesis, used in asthma treatment Acebutolol - ‫أﺳﯿﺒﯿﻮﺗﻮﻟﻮل‬ Echothiophate - ‫إﯾﻜﻮﺛﯿﻮﻓﯿﺖ‬ Edrophonium - ‫إﯾﺪروﻓﻮﻧﯿﻮم‬ Pancuronium - ‫ﺑﺎﻧﻜﻮروﻧﯿﻮم‬ Albuterol - ‫أﻟﺒﻮﺗﯿﺮول‬ Pilocarpine - ‫ﺑﺎﯾﻠﻮﻛﺎرﺑﯿﻦ‬ Atenolol - ‫أﺗﯿﻨﻮﻟﻮل‬ Esomolol - ‫إﯾﺴﻤﻮﻟﻮل‬ Finasteride - ‫ﻓﯿﻨﺎﺳﺘﯿﺮﯾﺪ‬ Pindolol - ‫ﺑﯿﻨﺪوﻟﻮل‬ Atropine - ‫أﺗﺮوﺑﯿﻦ‬ Pirenzepine - ‫ﺑﯿﺮﯾﻨﺰﯾﺒﯿﻦ‬ Benztropine - ‫ﺑﻨﺰﺗﺮوﺑﯿﻦ‬ Flumazenil - ‫ﻓﻠﻮﻣﯿﺰﯾﻨﯿﻞ‬ Guanethidine - ‫ﻏﻮاﻧﯿﺜﯿﺪﯾﻦ‬ Pralidoxime - ‫ﺑﺮاﻟﯿﺪوﻛﺴﺎﯾﻢ‬ Bethanechol - ‫ﺑﯿﺜﺎﻧﯿﻜﻮل‬ Propranolol - ‫ﺑﺮوﺑﺮاﻧﻮﻟﻮل‬ Botulinum toxins - ‫ﺗﻮﻛﺴﯿﻨﺎت اﻟﺒﻮﺗﻮﻟﯿﻨﯿﻮم‬ Hemicholinium - ‫ھﯿﻤﯿﻜﻮﻟﯿﻨﻮم‬ Ipratropium - ‫إﯾﺒﺮوﺗﺮوﺑﯿﻮم‬ Reserpine - ‫رﯾﺰرﺑﯿﻦ‬ Carbachol - ‫ﻛﺎرﺑﺎﻛﻮل‬ Rocuronium - ‫روﻛﻮروﻧﯿﻮم‬ Carvedilol - ‫ﻛﺎرﻓﯿﺪﯾﻠﻮل‬ Isoproterenol - ‫إﯾﺰوﺑﺮﺗﯿﺮﯾﻨﻮل‬ Labetalol - ‫ﻻﺑﯿﺘﺎﻟﻮل‬ Scopolamine - ‫ﺳﻜﻮﺑﻮﻻﻣﯿﻦ‬ Clonidine - ‫ﻛﻠﻮﻧﯿﺪﯾﻦ‬ Succinylcholine - ‫ﺳﺎﻛﺴﯿﻨﯿﻠﻜﻮﻟﯿﻦ‬ Cocaine - ‫ﻛﻮﻛﺎﯾﯿﻦ‬ Mecamylamine - ‫ﻣﯿﻜﺎﻣﯿﻼﻣﯿﻦ‬ Methacholine - ‫ﻣﯿﺜﺎﻛﻮﻟﯿﻦ‬ Timolol - ‫ﺗﯿﻤﻮﻟﻮل‬ Curare - ‫ﻛﻮراري‬ Tiotropium - ‫ﺗﯿﯿﻮﺗﺮوﺑﯿﻮم‬ Cyclopentolate - ‫ﺳﺎﯾﻜﻮﺑﻨﺘﻮﻟﯿﺖ‬ Metoprolol - ‫ﻣﯿﺘﻮﺑﺮوﻟﻮل‬ Metyrosine - ‫ﻣﯿﺘﯿﺮوﺳﯿﻦ‬ Trimethaphan - ‫ﺗﺮﯾﻤﯿﺜﺎﻓﺎن‬ Donepezil - ‫دوﻧﯿﺒﯿﺰﯾﻞ‬ Tropicamide - ‫ﺗﺮوﺑﯿﻜﺎﻣﯿﺪ‬ Dopamine - ‫دوﺑﺎﻣﯿﻦ‬ Neostigmine - ‫ﻧﯿﻮﺳﺘﯿﺠﻤﯿﻦ‬ Nicotine - ‫ﻧﯿﻜﻮﺗﯿﻦ‬ Varenicline - ‫ﻓﺎرﯾﻨﻜﻠﯿﻦ‬ Dutasteride - ‫دوﺗﺎﺳﺘﯿﺮﯾﺪ‬ Vesamicol - ‫ﻓﯿﺴﺎﻣﯿﻜﻮل‬ Nicotinic Agonists - ‫ﻣﺤﻔﺰات ﻧﯿﻜﻮﺗﯿﻨﯿﺔ‬ Nicotinic Antagonists - ‫ﻣﻀﺎدات ﻧﯿﻜﻮﺗﯿﻨﯿﺔ‬ Zileuton - ‫زﯾﻠﻮوﺗﻮن‬

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