Detection of Residual or Recurrent Disease PDF
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King Khalid University
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Summary
This document discusses the detection of residual or recurrent disease, focusing on the role of imaging techniques like MRI and CT in differentiating post-therapy changes from tumor recurrence. It highlights the significance of radiopharmaceuticals in diagnosis and the utility of PET scans in identifying recurrence.
Full Transcript
Detection of Residual or Recurrent Disease ▪ The role of identifying viable tumors by imaging is increasing because of the problems encountered by MRI and CT, especially after surgical, radiation, or chemotherapy treatment in differentiating post-therapy changes from residual viable tumor tissue, lo...
Detection of Residual or Recurrent Disease ▪ The role of identifying viable tumors by imaging is increasing because of the problems encountered by MRI and CT, especially after surgical, radiation, or chemotherapy treatment in differentiating post-therapy changes from residual viable tumor tissue, local recurrence, or necrosis. ▪ As a result different radiopharmaceuticals play an important role in different malignancies and for detecting recurrence. ▪ PET, and if not thalium-201, helps in detecting tumor recurrence and in differentiating tumor recurrence f necrosis as post-therapy changes that is difficult to differentiate based on CT or MRI. 15 Detection of Residual or Recurrent Disease Baseline (a) and follow-up (b) F-18-FDG-PET/CT studies of a 21-year-old man with Hodgkin’s lymphoma. The follow-up shows recurrent tumor at multiple lymph nodes and spleen 16