Detection of Residual or Recurrent Disease.pdf

Detection of Residual or Recurrent Disease ▪ The role of identifying viable tumors by imaging is increasing because of the problems encountered by MRI and CT, especially after surgical, radiation, or chemotherapy treatment in differentiating post-therapy changes from residual viable tumor tissue, lo...

Detection of Residual or Recurrent Disease ▪ The role of identifying viable tumors by imaging is increasing because of the problems encountered by MRI and CT, especially after surgical, radiation, or chemotherapy treatment in differentiating post-therapy changes from residual viable tumor tissue, local recurrence, or necrosis. ▪ As a result different radiopharmaceuticals play an important role in different malignancies and for detecting recurrence. ▪ PET, and if not thalium-201, helps in detecting tumor recurrence and in differentiating tumor recurrence f necrosis as post-therapy changes that is difficult to differentiate based on CT or MRI. 15 Detection of Residual or Recurrent Disease Baseline (a) and follow-up (b) F-18-FDG-PET/CT studies of a 21-year-old man with Hodgkin’s lymphoma. The follow-up shows recurrent tumor at multiple lymph nodes and spleen 16