Cardiopulmonary Exercise Testing (CPET) as Preoperative Test Before Lung Resection PDF

in vivo 28: 1013-1020 (2014) Review Cardiopulmonary Exercise Testing (CPET) as Preoperative Test Before Lung Resection ANASTASIOS KALLIANOS1, AGGELIKI RAPTI1, SOTIRIOS TSIMPOUKIS2, ANDRIANI CHARPIDOU2, IOANNIS DANNOS2, ELIAS KAINIS2...

in vivo 28: 1013-1020 (2014) Review Cardiopulmonary Exercise Testing (CPET) as Preoperative Test Before Lung Resection ANASTASIOS KALLIANOS1, AGGELIKI RAPTI1, SOTIRIOS TSIMPOUKIS2, ANDRIANI CHARPIDOU2, IOANNIS DANNOS2, ELIAS KAINIS2 and KONSTANTINOS SYRIGOS2 12nd Pulmonary Clinic, Sotiria General Hospital, Athens School of Medicine, Athens, Greece; 2Oncology Unit GPP, Sotiria General Hospital, Athens School of Medicine, Athens, Greece Abstract. Lung resection is still the only potentially curative comorbidities, thus are excluded from surgery and directed therapy for patients with localized non-small lung cancer toward medical or non-invasive treatments. Given the recent (NSCLC). However, the presence of cardiovascular advances in operative techniques and perioperative care, comorbidities and underlying lung disease increases the risk which have considerably reduced surgical morbidity and of postoperative complications. Various studies have evaluated mortality, an effort is being made to expand the group of the use of different preoperative tests in order to identify candidates for surgical resection. patients with an increased risk for postoperative complications, Postoperative cardiopulmonary complications include associated with prolonged hospital stay and increased respiratory failure (acute respiratory distress syndrome, morbidity and mortality. In this topic review, we discuss the ARDS), prolonged postoperative mechanical ventilation or role of cardiopulmonary exercise testing (CPET) as one of the reintubation, pneumonia, atelectasis requiring bronchoscopy, preoperative tests suggested for lung cancer patients scheduled myocardial infarction, and arrhythmias requiring intravenous for lung resection. We describe different types of exercise treatment. Various single and combined parameters of testing techniques and present algorithms of preoperative functional operability have been proposed to assess the evaluation in lung cancer patients. Overall, patients with surgical risk. Pulmonary function tests adequately assess the maximal oxygen consumption (VO2max)