Connective Tissue.pdf

Connective tissue supports and their associated extracellular matrix arenchymal cells provide the main function of a hisue Support cells provide the structural scaffolding for the chisue Connective dense loose and tissue can be separated into 2 types their is also other specialized types Spe...

Connective tissue supports and their associated extracellular matrix arenchymal cells provide the main function of a hisue Support cells provide the structural scaffolding for the chisue Connective dense loose and tissue can be separated into 2 types their is also other specialized types Specialized connective tissue dense tendons regular connective tissue which is found in ligaments cartilidge adipose tissue haemopoichi tissue blood bone 5 main cells that make 1 fibroblasts secrete tissues tissue 2 3 usually tissue extracellular matrix connective irregular tissue of cartlidge Osteoblasts bone in most Creates areolar and elastin tissue and dense regular or collagen loose connective Chondrocytes components secrete secrete extracellular matrix extracellular matrix components components of 4 Myo fibroblasts 5 function lipid Adipocytes energy as a serete EMC storing and contractile support cells act as have endocrine function and act store physical padding in some anatomic regions FEATURES Embryological derivation from mesenchyme Production of a variety of extracellular matrix components when formation of sparesly cellular tissues the matrix is the main component mature in which Cell adhesion rather than mechanisms other cells that interact with ECM ECM Composed of e.g Ground substance fibrillar protiers and ground substance Elastin fibrillerproteins Collagen contains GAGS hylauronic acid it is transparent glycoprotein aggregan colourless and resides in between fibres and cells Names denote function Blast Build cyte maintain clast remove FIBROBLASTS Secrete Collagen least specialised cells found in ECM elastin but can differentiate into other actively Spindle shaped Cytoplasm is basophilic H E stain Adults are less active are stained less by matrix stains alot using secrete so called fibrocytes E stain H which BONE osteoclasts and osteocytes Made up of osteoblasts ELM of Bone is produced by osteoblasts and called osteoid is majority collagen type I CARTILIDGE ADIPOCYTES Intracellular storage of fat unilocular and mutilocular 2x types can get white which is due to less and larger droplets or brown mitochondria which contains higher mitochondria ion and smaller lipid droplets MYOFIBROBLASTS Important for injury response Spindle shaped cells that secrete collagen also have contractile properties when glands are present myo epithelial cells her between epithelial cells and basement membrane of duct BLOOD LYMPH Examples of macrophages cells within connective tissue include mast cells plasma cells