Compre Exam May 2023 SET A & B PDF

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Summary

This is a chemistry exam paper for May 2023. The paper contains questions and answers related to different chemistry concepts.

Full Transcript

SET A Questions 1. In which disease state has severely increase conjugated 1 bilirubin Choices Answer a. Biliary obstruction b. Hemolysis c. Erythroblastosis fetalis d. Neonatal jaundice biliary obstruction a. quality control b. system calibration c. quality assurance d. system stdardization Quality...

SET A Questions 1. In which disease state has severely increase conjugated 1 bilirubin Choices Answer a. Biliary obstruction b. Hemolysis c. Erythroblastosis fetalis d. Neonatal jaundice biliary obstruction a. quality control b. system calibration c. quality assurance d. system stdardization Quality assurance 2 2. The process in which lab aspect include pxn info, specimen collection, equipment maintenance and reporting 3 3. Children >1 yr old can be pricked provided that it is in 3rd or a. true 4th finger b. false 4 4. All of the ff can be used in UV range except: a. tungsten b. hydrogen discharge c. deuterium d. all 5. Precipitating agents used in removing VLDL and LDL so that 5 HDL will remain, EXCEPT a. Phosphotungstate/magnesium b. Citrate/fluoride c. Heparin/ manganese d. dextran sulfate TRUE Tungsten Citrate/ flouride 6 6. Reflectance spectrophotometry is principle used in: a. Technicon b. kodak c. du pont d. beckman a. 10 7. The +/-2 Sd acceptable for digoxin control is 2.0-2.6 ng/ml. On b. 20 7 ave, the is the expected value if > 2.6 ng/ml is 1 in c. 40 d. 100 8 Which of RBC following can detect random errors? 9 What is the most specific dye binding technique will bind to albumin 10 Which of these will be used to compare past result with the recent result 11 BUN is 22 mg/dL. What is the SI value? 13s and R4s a. Bromocresol blue, b. Bromocressol pulple, c. Bromocresol green, d. Tetraphenol blue Kodak b. 20 13s & R4s Bromcresol purple Delta check 7.8 (mmol/L) A. Thyroxine Which hormone is responsible for converting inactive Vitamin D B. Parathyroid hormone 12 to Vitamin D3 and is important in calcium metabolism C. Epinephrine D. Calcitonin 7.8 (mmol/L) PTH 13. Enzyme that catalyzes the hydrolysis of urea to ammonium urease 13 ion and bicarbonate Catalyze uricase 14 14. Purpose of ampholyte in isoelectric focusing 15 15. Standard solution in measuring icterus index 16 potassium dichromate 16.how much sodium chloride must be dissolved to prepare 500ml of 5 molar solution Given MW = 58.44 g 17 17. Fasting blood sugar normal value 18 A. Maintain pH of buffer B. Establish pH gradient C. Establish current flow D. Keep proteins in charges state 18. Berthelot reaction, contaminant that causes urea to be falsely elevated 19 Positioned right angle in fluorescence spectrophotometry B. Establish pH gradient for migration 0.01% potassium dichromate 146. 1 70-99 bacteria, ammonia A. Primary and Secondary Monochromator B. Secondary monochromator and detector C. Primary monochromator and cuvet D. Secondary Monochromator and Cuvet 20 20. Glucose polarographic oxygen electrode 21 Amount of 8N H2SO4 to neutralize 45ml of 6N KOH urease 70-99 mg/dl ammonia B Secondary monochromator and detector Glucose Oxidase 1. 60 ml, 2. 33.6ml, 3. 56ml, 4. 33.6 ml 22 Serum BUN levels are affected by the following, Except 23 1. Protein intake, 2. Liver function, 3. Kidney function, 4. Muscle mass 1. leukemia, Patient with elevated WBCs and serum urea, and normal levels 2. glomerular nephritis, of serum creatinine and uric acid has? 3. I forgor 24 Endogenous substance to test for glomerular filtration A. uric acid B. urea nitrogen C. creatinine D. 1. Inulin, Endogenous substance filtered by the glomerulus, not 2. Creatinine, 25 reabsorbed by tubules (only when blood concentration is high) 3. Para aminohippurate, 4. I forgor 26 NPN increase in plasma Indicator of Reye's syndrome A. Creatinine B. Ammonia C. Urea D. Uric Acid 27 SI conversion of 2.3 mg/dL serum creatinine a. 19.3 umol/l b. 203.3 umol/l c. 305 umol/l d. 226.3 umol/l 28 Impaired glucose value after 2 hrs post glucose test OGTT a. 139 mg/dl b. 105 mg/dl c. 150 mg/dl d. 240 mg/dl 29 Reference electrode of hydrogen ions Muscle Mass glomerular nephritis Creatinine Creatinine Ammonia 203.32 150 mg/dL glass membrane 30 Coefficient of variation; Mean = 89 mg/dl; 2SD = 14mg/dL a. 15.7 b. 15.8 c. 7.8 d. 7.9 31 Jendrassik-Grof color developer a. Caffein acetate b. Alkaline tartrate c. Sodium acetate d. Ascorbic Acid Alkaline Tartrate 32 Coomasie Brilliant Blue 250 used in dying a. CSF protein b. Serum albumin c. Both d. Neither CSF Protein 33 Molarity 2N H2SO4 34 Frederick Hyperlipidemia D. 7.9 1 A. Type 1 B. Type 2 C. Type 3 D. Type 4 35 Expected true value glucose Type 2 70 to 99mg/dL 36 Blood urea nitrogen synthesis in A. Kidney B. Liver C. Thyroid D. I forgot 37 measurement of True glucose thru colorimetric folin wu benedict nelson glucose oxidase Liver Glucose oxidase 38 Increase in albumin conc. chronic hepatitis cancer of pancreas nephrotic syndrome dehydration 39 OGTT prep Except A. carbs lower than 150g/day for 3 days before B. no food, tea, coffee, smoking 8 hrs before or during C. administration of 75 grams glucose load D. nota 40 HPLC stationary and mobile solid and liquid liquid and gas solid and gas stationary - solid and mobile - liquid 41 2 protein for bilirubin uptake albumin and glucoronic acid albumin and ligandin ligandin and z protein nota Ligandin and Z protein 42 Dictate non diabetes fasting >140 random of 205 two-hour >200 hba1c = 6.2 43 Lipoprotein and triglyceride prep NPO 12midnight to 7am NPO of at least 8hrs NPO of at least 12 hrs blood can be taken anytime 44 analyte to use in measuring glomerular filtration rate a. creatinine b. glucose c. uric acid d. urea nitrogen dehydration A HbA1c = 6.2% NPO of at least 12 hrs a. creatinine 45 tests that require fasting 46 picric acid and sodium hydroxide used in what colorimetric method 1. fbs 2. trigly 3. chole 4. inorganic phosphate A. Jaffe B. Fearon C. Biuret D. nessler 1,2,4 A. Jaffe 47 characteristic of type 1 diabetes mellitus a. most common dm b. most common in 40yo c. requires ogtt for dx d. requires insulin replacement to prevent ketosis 48 substance that has circadian rhythm Albumin Calmodulin Serum Cortisol TSH 49 Which principle about fluorometry is true? A. fluorescence is directly proportional to temperature B. light emitted is higher energy than light absorbed more sensitive than spectrophotometry C. fluorometry more sensitive than spectrophotometry D. most frequently used: incandescent tungsten lamp 50 Which lipid, when analyzed, would be most affected by a random blood sample? Triglyceride cholesterol LDL HDL D. requires insulin replacement to prevent ketosis Cortisol Triglycerides 51 Which Westgard results indicate a random error? - 13s 41s - 22s R4s - 13s R4s - 10mean 12s What anticoagulant prevents the clotting of blood through 52 chelation? - oxalate - fluoride - EDTA - citrate 53 protein electrophoresis pattern in plasma compared to serum A. diffuse pattern because of anticoagulant B. broad prealbumin peak C. decrease globulin peak D. sharp fibrinogen peak 54 What globulin fraction is conjugated and covalently bound to albumin? 55 Index of precision is statistically represented by alpha beta delta mode median mean coefficient of variation 56 Increase positive risk for coronary heart? EDTA D. Sharp fibrinogen peak delta coefficient of variation HDL60 B. LDL 6.5% is diabetic CC pg 113 Collection of blood for triglyceride testing should be done after a 12hour fasting period, when same w/ set B chylomicrons have ordinarily been cleared from the circulation. google CC1 lec p30; SIM Lab page 5 July 2022 recalls google cc1 page 44 under Fluorometry Reagent 1(R1) : Sodium hydroxide 0.2 mol/l, Reagent 2 (R2) : Picric acid 20 mmol/l Random error - 12s, 13s, r4s systematic - 22s, 41s, 10mean google EDTA chelates calcium quizlet and CC1 page 131 Fibrinogen is one of the largest proteins in blood plasma and it's only seen in plasma. CC 1 module p.164 july 2022 recalls CC 1 module p.18 Coefficient of variation montiored to assess consistency and precision Increase positive risk for coronary heart? CC1. p.114 Triglyceide NV: 60-150 mg/dL; Chole NV: 140-200 mg/dL 5 mol/L x 0.5 L x 58.44 g = 146.1 g same question sa #16 LDL = TC - HDL - 0.2 x TG CC2 p. 81; national boards flashcard for blood bank Add everything and divide by how Sorry I forgot the numbers many numbers you added. I think pero madali lang naman to 10 yun so Total/10 cc pg. 40 July 2022 I think converts transmitted light recalls- into into electrical energy un and then electrical energy detector is the answer bc low good cholesterol HDL NV: 4075mg/dl same w/ 79-85 set c ng 2nd take CC 1 lec p. 165 Jendrassik-Grof: color developer - alkaline Accelerates the coupling of tartrate bilirubin with diazotized sulfanilic pangidentify ng total and acid conjugated bilirubin - caffeine sodium benzoate dissociating agent - methanol Estradiol: most potent Estron: menopause LD1: HA; LD3: Pancreatitis; LD4: Hepatic Disease Quizlet Cushing syndrome=Low potassium, high sodium (Low Po CrUSH *HisHis) Hello po crush *hehe kinilig na sound with S Addison's disease= Low sodium, High Potassium (si Addi mahilig HiPo sa LoSo) hipo sa soso causes hypercalcemia, since baliktad sila ni phosphate, hypophosphate Decreased Adrenal Activity: metabolic acidosis, high potassium, low renin, low BP, low blood sugar, low sodium--Increased Adrenal Activity: alkalosis, increased sodium and renin, low potassium and hydrogen CC1 p. 67 july 2022 recalls CC2 p. 82 pO2 electrode - polographic/Clark electrode, amperometric CC2 p. 57 Jan 2023 recalls CC2 p. 78-80 Hyperventilation - respiratory alkalosis starvation- metabolic acidosis vomiting- metabolic alkalosis TSH: Diurnal; Cortisol: Circadian -could be TSH din idk Liver: most rapid; most anodal; Bone: heat labile; Placenta: heat stable; Intestine: slowest CC2 p. 150 CC p.78 AG = (Na) - (HCl + HCO3) sodium - Hydrogen chloride+bicarbonate HCO3 - metabolic pCO2 - respiratory CC2 p. 78 CC2 p. 31 Lab picture of metabolic acidosis: -Decreased pH, ctCO2, HCO3, pCO2 -Increased Anion gap -hyperkalemia Liver: most rapid; most anodal; Bone: heat labile; Placenta: heat stable; Intestine: slowest CC1 lab p 18 July 2022 recalls CC1 lec p. 21 other name: Shewhart Cusum - earliest indication of a trend Youden plot - interlab quality ctrl programs Gaussian -plotting values from multiple analyses (600 / 300) x 1= 2 CC1 p. 113 (Patient Preparation) CC2 p. 81 *If heparinized plastic syringe: decreased pH, increase pO2, decreased pCO2.... *blood samples requires ice to prevent oxygen consumption leading to acid formation....hence @ RT; it coud be decreased pH, increased pCO2, decreased pO2 correct kasi arterial blood meaning oxygenated, if exposed to room air will be consumed by CO2 CC2 p. 44 Cardiac Markers: 1. CK-MB 2. CKMM 3. CK/CPK 4. AST/SGOT 5. LDH 6. ALD 7. Myoglobin 8. Troponin I 9. Troponin T CC1 p. 133, 3rd bullet CC2 p. 44 thru kidney by PTH, produced active D3 CC2 p. 62; CC2 pp.17, 19 July 2022 recalls Anterior pituitary hormones: LH, FSH, TSH, ACTH, GH, Prolactin CC2 p. 110 Parathyroid glands: PTH Quizlet 2022 recalls July tetany def. calcium wacker (forward: lactatepyruvate) CC2 p. 50 2Na + (glucose/20) + (BUN/3) OR 1.86 Na + (glucose/18) + (BUN/2.8) +9 Polypeptides: Insulin, glucagon, PTH, GH, prolactin Glycoproteins: FSH, LH, TSH, HCG CC2 p. 103 July 2022 recalls q#81 Amines Tyrosine: T3, T4, epinephrine, norepinephrine Tryptophan: melatonin Steroids Adrenal glands: cortisol, aldosterone Gonads: ovaries, testes Placenta: testosterone, estrogen, progesterone CC2 p. 121 CC pg 81. Heparinized plastic syringe is downward shift of blood pH, increase PO2, decrease PCO2 *Aldosterone is controlled by (RAAS) renin-angiotensinaldosterone-system *Stimuli to aldosteron secretion: Increase: Serum potassium, ACTH level, Estrogen level Decreased: Serum sodium, Blood volume Reference Rationale Additional Notes https://quizlet.com/416017278/liver-porphyrins-thyroid-flash-cards/ biliverdin > bilirubin > urobilinogen parang creatinine kasi enzymatic yung LDLcreatinine po ata kasi nagccompute pa to measure LDL eh Quality controls only detect errors in testing Precipitants: heparin/Mn Phosphotungstate/Mg dextran sulfate Polyethylene glycol CC. pg 38 CC1 page 105. And also so 50% Brainly dapat ang answer 0.357 90 x 0.05555 = 4.99. (CF: 0.05555) 14/2 = 7/89 x 100 CC1 page 91 True lahat ng choices except sa 7%. reference range ng Glycated hemoglobin is 4-6% lang methanol ang sabi ng internet Jendrassik-Grof: color developer - alkaline tartrate pangidentify ng total and conjugated bilirubin - caffeine sodium benzoate dissociating agent - methanol 50g/.6L, note na dapat per liter yung volume see page 125 CClec reference methof for protein Same w/ 1-7 Set C Same w/ 1-7 Set C p. 145 CC gout is excess uric acid CC1 p139 July 2022 recalls google pituitary produces peptide hormones (TSH, FSH, etc) Apolipoprotein increase risk in Alzheimer's primary hypothroid: low T4/T3, normal TSH secondary: both decreased Dictate non diabetes amylase faster, but lipase is more specific. amyslase can also elevate in parotid gland problems same concept as number 64 Google lipase is more specific, but amylase is first to rise, but not as specific cc 2 module p. 66 CC1 p. 108 CC 2 module p. 78 AG = Na - (HCO3 + HCl) CC 2 module p. 62 & 142 Jendrassik-Grof: color developer - alkaline tartrate pangidentify ng total and conjugated bilirubin - caffeine sodium benzoate dissociating agent - methanol Inverse relationships: Calcium and Phosphorus, Biicarbonate and Chloride, Sodium and Potassium cannabis = weed = marijuana CC 2 module p.44 CC 2 module p.13 highest levels of total LD in pernicious anemia and hemolytic disorders CK-MM: highest in Duchenne CC1 p. 106 APO B - LDL Trust me bro trend - consistent direction change (6 consecutinve pababa) shift - sudden consistent change (dating below mean biglang 6 consecutive above mean) correct daw sabi ni google, but my rationale was, acids can reduce metals, uric acid is an acid, therefore uric acid can reduce tungsten (a metal) d cholesterol)

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